IE35428B1 - Benzodiazepine derivatives - Google Patents

Benzodiazepine derivatives

Info

Publication number
IE35428B1
IE35428B1 IE1624/70A IE162470A IE35428B1 IE 35428 B1 IE35428 B1 IE 35428B1 IE 1624/70 A IE1624/70 A IE 1624/70A IE 162470 A IE162470 A IE 162470A IE 35428 B1 IE35428 B1 IE 35428B1
Authority
IE
Ireland
Prior art keywords
benzodiazepine derivatives
coch
gb1332699a
carbobenzoxyamino
phthalimido
Prior art date
Application number
IE1624/70A
Other versions
IE35428L (en
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IE35428L publication Critical patent/IE35428L/en
Publication of IE35428B1 publication Critical patent/IE35428B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/28—Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

1332699 Benzophenones F HOFFMANNLA ROCHE & CO AG 21 Dec 1970 [1 June 1970] 12291/72 Heading C2C Compounds of the general formula (R 1 = H, Me; R 2 = H, -COCH 3 , -COCH 2 X; X = leaving atom or group, carbobenzoxyamino, phthalimido) are prepared by introducing the 5-iodo substituent using iodine in presence of an oxidizing agent. [GB1332699A]
IE1624/70A 1970-06-01 1970-12-21 Benzodiazepine derivatives IE35428B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4253370A 1970-06-01 1970-06-01

Publications (2)

Publication Number Publication Date
IE35428L IE35428L (en) 1971-12-01
IE35428B1 true IE35428B1 (en) 1976-02-18

Family

ID=21922438

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1624/70A IE35428B1 (en) 1970-06-01 1970-12-21 Benzodiazepine derivatives

Country Status (15)

Country Link
AR (1) AR193050A1 (en)
BE (1) BE760510A (en)
BG (3) BG18187A3 (en)
CH (2) CH549586A (en)
DE (1) DE2062927A1 (en)
DK (1) DK136647B (en)
ES (1) ES386685A1 (en)
FR (1) FR2093923B1 (en)
GB (1) GB1332699A (en)
IE (1) IE35428B1 (en)
IL (1) IL35885A (en)
NL (1) NL7018577A (en)
NO (1) NO130681C (en)
PH (1) PH9829A (en)
SE (2) SE385298B (en)

Also Published As

Publication number Publication date
GB1332699A (en) 1973-10-03
SE7513327L (en) 1975-11-26
IE35428L (en) 1971-12-01
BE760510A (en) 1971-06-18
BG18188A3 (en) 1974-09-02
NO130681C (en) 1975-01-22
AR193050A1 (en) 1973-03-30
NO130681B (en) 1974-10-14
IL35885A0 (en) 1971-04-28
IL35885A (en) 1974-05-16
BG18187A3 (en) 1974-09-02
PH9829A (en) 1976-04-02
BG18186A3 (en) 1974-09-02
DK136647B (en) 1977-11-07
FR2093923A1 (en) 1972-02-04
CH549586A (en) 1974-05-31
NL7018577A (en) 1971-12-03
FR2093923B1 (en) 1974-05-24
CH561684A5 (en) 1975-05-15
DE2062927A1 (en) 1971-12-16
SE385298B (en) 1976-06-21
DK136647C (en) 1978-04-17
ES386685A1 (en) 1973-03-16

Similar Documents

Publication Publication Date Title
IE36725L (en) Tetrazole derivatives.
IE35416B1 (en) Compositions for the control of plant-pathogenic organisims
GB1305442A (en)
IE35209L (en) 3, 4-dihydroisoquinoline derivatives.
CA992538A (en) 2-phenyl-as-triazine-3,5(2h,4h)diones and derivatives thereof and compositions containing said compounds
BE823171A (en) N, N-dialkylaminocarbamates of substituted hydroxy-pyridine derivatives.
ES415226A1 (en) Method of enhancing vincamine compositions
GB1292737A (en) Haloepoxides
IE35428B1 (en) Benzodiazepine derivatives
GB1294776A (en) A process for the manufacture of benzodiazepine derivatives
GB1261060A (en) Phthalen-1-one derivatives
JPS5233624A (en) Preparation of leucylnitroagmatines
GB1442222A (en) Benzodiazepine derivatives
JPS5211845A (en) Address information check system
GB1253370A (en) Benzodiazepine derivatives, salts thereof, and processes for making them
JPS5254084A (en) Manufacture of 2-gamma-glutamylamino-4-hexynic acid and/or 2-gamma-glutamylamino- 3-hydroxy-4-hexynic acid
JPS5233662A (en) Preparation of n2-naphthalenesulfonyl-alginamides and acid addition sa lts thereof
CA990285A (en) 1,2-dihydroquinobenzoxa(or thia)zepine derivatives
CA835391A (en) 5,6-dihydro-5-oxo-11h-pyrido (2,3-6) (1,5) benzodiazepine compounds
JPS5412385A (en) Carbostyril derivative
CA956313A (en) 1,4-dihydro-1,4-etheno-isoquinolin-3(2h)-ones
CA807668A (en) Derivatives of pentachloro- (or bromo)-9-oxa-2-tricyclo/2.2.1.25,7/nonene
CA981666A (en) 5,11-dihydrodibenzoxa(or thia)zepine derivatives
AU458171B2 (en) 4, 6 DIIODO-1 ISOPROPOXYCARBONYL TRIFLUOROMETHYL BENZI ml DAZOLE
BE835282A (en) IMIDAZO DERIVATIVES (1.28) ISOQUINOLEINE