GB1360367A - Derivatives of 4,-aminomethyl-dibenzo-b,e- 11-oxepine-2,- spiro- 1,3, -dioxolane their method of preparation and their thera peutic application - Google Patents
Derivatives of 4,-aminomethyl-dibenzo-b,e- 11-oxepine-2,- spiro- 1,3, -dioxolane their method of preparation and their thera peutic applicationInfo
- Publication number
- GB1360367A GB1360367A GB287973A GB287973A GB1360367A GB 1360367 A GB1360367 A GB 1360367A GB 287973 A GB287973 A GB 287973A GB 287973 A GB287973 A GB 287973A GB 1360367 A GB1360367 A GB 1360367A
- Authority
- GB
- United Kingdom
- Prior art keywords
- oxepine
- dioxolane
- spiro
- dibenzo
- aminomethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
1360367 Alkyl derivatives of 4<SP>1</SP>-aminomethyldibenzo - [b,e] - 11 - oxepine - 2<SP>1</SP> - spiro - 1<SP>1</SP>,3<SP>1</SP>- dioxolane DELALANDE SA 19 Jan 1973 [15 Dec 1972] 2879/73 Addition to 1359951 Heading C2C Alkyl derivatives of 4<SP>1</SP>-aminomethyl-dibenzo- [b,e] - 11 - oxepine - 2<SP>1 </SP>- spiro - 1 1 ,3<SP>1</SP> - dioxolane of formula which R represents an alkyl group having 1 to 4 carbon atoms are claimed per se. These compounds are prepared by condensing, in a benzene medium, 4<SP>1 </SP>- bromomethyl - dibenzo - [b,e]- 11 - oxepine - 2<SP>1</SP>- spiro - 11,31 - dioxolane of formula with a primary amine of formula R-NH 2 in which R has the same significance as in above. The compounds are used as pharmaceuticals.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7244842A FR2210390B2 (en) | 1972-12-15 | 1972-12-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1360367A true GB1360367A (en) | 1974-07-17 |
Family
ID=9108796
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB287973A Expired GB1360367A (en) | 1972-12-15 | 1973-01-19 | Derivatives of 4,-aminomethyl-dibenzo-b,e- 11-oxepine-2,- spiro- 1,3, -dioxolane their method of preparation and their thera peutic application |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS5336476B2 (en) |
AU (1) | AU467009B2 (en) |
BE (1) | BE794902A (en) |
CA (1) | CA985291A (en) |
CH (1) | CH558793A (en) |
ES (1) | ES411018A2 (en) |
FR (1) | FR2210390B2 (en) |
GB (1) | GB1360367A (en) |
IT (1) | IT1055523B (en) |
LU (1) | LU66975A1 (en) |
NL (1) | NL7301487A (en) |
SE (1) | SE394890B (en) |
ZA (1) | ZA73487B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS53149771U (en) * | 1977-04-28 | 1978-11-25 | ||
JPH0518615Y2 (en) * | 1987-10-02 | 1993-05-18 |
-
0
- BE BE794902D patent/BE794902A/en unknown
-
1972
- 1972-12-15 FR FR7244842A patent/FR2210390B2/fr not_active Expired
-
1973
- 1973-01-19 GB GB287973A patent/GB1360367A/en not_active Expired
- 1973-01-23 ZA ZA730487A patent/ZA73487B/en unknown
- 1973-01-25 CH CH104573A patent/CH558793A/en not_active IP Right Cessation
- 1973-01-26 ES ES411018A patent/ES411018A2/en not_active Expired
- 1973-02-01 NL NL7301487A patent/NL7301487A/xx not_active Application Discontinuation
- 1973-02-02 JP JP1303273A patent/JPS5336476B2/ja not_active Expired
- 1973-02-05 IT IT67234/73A patent/IT1055523B/en active
- 1973-02-06 LU LU66975A patent/LU66975A1/xx unknown
- 1973-02-07 AU AU51888/73A patent/AU467009B2/en not_active Expired
- 1973-02-26 CA CA164,593A patent/CA985291A/en not_active Expired
- 1973-03-14 SE SE7303565A patent/SE394890B/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU5188873A (en) | 1974-08-08 |
DE2304224B2 (en) | 1977-04-21 |
CH558793A (en) | 1975-02-14 |
NL7301487A (en) | 1974-06-18 |
ES411018A2 (en) | 1977-07-01 |
LU66975A1 (en) | 1973-08-17 |
ZA73487B (en) | 1973-10-31 |
BE794902A (en) | 1973-08-02 |
JPS4987686A (en) | 1974-08-22 |
AU467009B2 (en) | 1975-11-13 |
FR2210390A2 (en) | 1974-07-12 |
FR2210390B2 (en) | 1976-07-02 |
DE2304224A1 (en) | 1974-06-20 |
CA985291A (en) | 1976-03-09 |
SE394890B (en) | 1977-07-18 |
JPS5336476B2 (en) | 1978-10-03 |
IT1055523B (en) | 1982-01-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed | ||
PCNP | Patent ceased through non-payment of renewal fee |