ES428379A1 - Carbazole derivatives and anti-inflammatory preparations containing them - Google Patents
Carbazole derivatives and anti-inflammatory preparations containing themInfo
- Publication number
- ES428379A1 ES428379A1 ES428379A ES428379A ES428379A1 ES 428379 A1 ES428379 A1 ES 428379A1 ES 428379 A ES428379 A ES 428379A ES 428379 A ES428379 A ES 428379A ES 428379 A1 ES428379 A1 ES 428379A1
- Authority
- ES
- Spain
- Prior art keywords
- carbazole derivatives
- preparations containing
- inflammatory preparations
- inflammatory
- novel compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Novel carbazole derivatives are prepared which correspond to the formula < IMAGE > in which the radicals R1, R2, R3, R4, R5, R6 and R7 have the meaning given in Claim 1. These novel compounds are obtained by dehydrogenation of corresponding 1,2,3,4- or 5,6,7,8-tetrahydro-carbazole derivatives. The novel compounds are distinguished on topical administration by a strong anti-inflammatory activity.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2337154A DE2337154C2 (en) | 1973-07-18 | 1973-07-18 | New carbazole derivatives |
| DE2431292A DE2431292A1 (en) | 1974-06-27 | 1974-06-27 | Anti-inflammatory carbazole derivs - specif. e.g. 1-ethoxycarbonyl-6-methoxy-carbazole and 8-methyl-carbazole-1-carboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES428379A1 true ES428379A1 (en) | 1976-09-16 |
Family
ID=25765532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES428379A Expired ES428379A1 (en) | 1973-07-18 | 1974-07-17 | Carbazole derivatives and anti-inflammatory preparations containing them |
Country Status (20)
| Country | Link |
|---|---|
| JP (1) | JPS5069072A (en) |
| AT (1) | AT342583B (en) |
| BG (1) | BG25793A3 (en) |
| CA (1) | CA1053682A (en) |
| CH (1) | CH619213A5 (en) |
| CS (1) | CS190431B2 (en) |
| DD (1) | DD114075A5 (en) |
| DK (1) | DK388074A (en) |
| ES (1) | ES428379A1 (en) |
| FI (1) | FI218874A (en) |
| FR (1) | FR2237628B1 (en) |
| GB (1) | GB1482771A (en) |
| HU (1) | HU173115B (en) |
| IE (1) | IE39624B1 (en) |
| IL (1) | IL45298A (en) |
| NL (1) | NL7409715A (en) |
| NO (1) | NO742601L (en) |
| RO (1) | RO72713A (en) |
| SE (1) | SE396602B (en) |
| SU (1) | SU511855A3 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060074124A1 (en) * | 2003-09-12 | 2006-04-06 | Andrew Napper | Methods of treating a disorder |
| JP4908215B2 (en) * | 2003-09-12 | 2012-04-04 | エリクサー ファーマスーティカルズ インコーポレイテッド | Treatment of disease |
| US8143257B2 (en) * | 2004-11-23 | 2012-03-27 | Ptc Therapeutics, Inc. | Substituted phenols as active agents inhibiting VEGF production |
| AR088377A1 (en) | 2011-10-20 | 2014-05-28 | Siena Biotech Spa | PROCESS FOR THE PREPARATION OF 6-CHLORINE-2,3,4,9-TETRAHIDRO-1H-CARBAZOL-1-CARBOXAMIDE AND INTERMEDIATE COMPOUNDS OF THIS |
| CA3059631A1 (en) * | 2017-04-11 | 2018-10-18 | Saje Pharma, Llc | Carbazole compounds and methods of use thereof |
| JP2021134141A (en) * | 2020-02-21 | 2021-09-13 | エヌ・イーケムキャット株式会社 | Method for producing aromatic compound using heterogeneous noble metal catalyst |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7008628A (en) * | 1969-06-25 | 1970-12-29 |
-
1974
- 1974-07-15 BG BG027244A patent/BG25793A3/en unknown
- 1974-07-16 DD DD179943A patent/DD114075A5/xx unknown
- 1974-07-17 ES ES428379A patent/ES428379A1/en not_active Expired
- 1974-07-17 HU HU24SC483A patent/HU173115B/en unknown
- 1974-07-17 CS CS745109A patent/CS190431B2/en unknown
- 1974-07-17 NO NO742601A patent/NO742601L/no unknown
- 1974-07-17 FI FI2188/74A patent/FI218874A/fi unknown
- 1974-07-17 SE SE7409330A patent/SE396602B/en unknown
- 1974-07-18 JP JP49082669A patent/JPS5069072A/ja active Pending
- 1974-07-18 IE IE1519/74A patent/IE39624B1/en unknown
- 1974-07-18 AT AT596074A patent/AT342583B/en active
- 1974-07-18 SU SU2048652A patent/SU511855A3/en active
- 1974-07-18 CH CH990174A patent/CH619213A5/en not_active IP Right Cessation
- 1974-07-18 NL NL7409715A patent/NL7409715A/en not_active Application Discontinuation
- 1974-07-18 CA CA205,063A patent/CA1053682A/en not_active Expired
- 1974-07-18 DK DK388074A patent/DK388074A/da not_active Application Discontinuation
- 1974-07-18 IL IL45298A patent/IL45298A/en unknown
- 1974-07-18 RO RO7479524A patent/RO72713A/en unknown
- 1974-07-18 GB GB31966/74A patent/GB1482771A/en not_active Expired
- 1974-07-18 FR FR7424991A patent/FR2237628B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| BG25793A3 (en) | 1978-12-12 |
| DD114075A5 (en) | 1975-07-12 |
| GB1482771A (en) | 1977-08-17 |
| IL45298A (en) | 1980-01-31 |
| CH619213A5 (en) | 1980-09-15 |
| IE39624B1 (en) | 1978-11-22 |
| FI218874A (en) | 1975-01-19 |
| IE39624L (en) | 1975-01-18 |
| ATA596074A (en) | 1977-08-15 |
| SE7409330L (en) | 1975-01-20 |
| JPS5069072A (en) | 1975-06-09 |
| NL7409715A (en) | 1975-01-21 |
| NO742601L (en) | 1975-02-17 |
| CA1053682A (en) | 1979-05-01 |
| FR2237628A1 (en) | 1975-02-14 |
| SE396602B (en) | 1977-09-26 |
| DK388074A (en) | 1975-03-03 |
| CS190431B2 (en) | 1979-05-31 |
| RO72713A (en) | 1982-09-09 |
| SU511855A3 (en) | 1976-04-25 |
| HU173115B (en) | 1979-02-28 |
| FR2237628B1 (en) | 1977-05-20 |
| AT342583B (en) | 1978-04-10 |
| IL45298A0 (en) | 1974-10-22 |
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