ES421598A1 - Un procedimiento para la sintesis de piridonas. - Google Patents
Un procedimiento para la sintesis de piridonas.Info
- Publication number
- ES421598A1 ES421598A1 ES421598A ES421598A ES421598A1 ES 421598 A1 ES421598 A1 ES 421598A1 ES 421598 A ES421598 A ES 421598A ES 421598 A ES421598 A ES 421598A ES 421598 A1 ES421598 A1 ES 421598A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- temperature
- halogenated compound
- pharmaceutical composition
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00315836A US3839346A (en) | 1972-12-18 | 1972-12-18 | N-substituted pyridone and general method for preparing pyridones |
| US38065573A | 1973-07-19 | 1973-07-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES421598A1 true ES421598A1 (es) | 1977-01-01 |
Family
ID=26980095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES421598A Expired ES421598A1 (es) | 1972-12-18 | 1973-12-18 | Un procedimiento para la sintesis de piridonas. |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS4987677A (zh) |
| DE (2) | DE2366349C2 (zh) |
| ES (1) | ES421598A1 (zh) |
| FR (1) | FR2232316B1 (zh) |
| GB (2) | GB1458049A (zh) |
| NL (1) | NL7317316A (zh) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1049411A (en) * | 1972-12-18 | 1979-02-27 | Affiliated Medical Research | N-substituted pyridone and general method for preparing pyridones |
| JPS5350179A (en) * | 1976-10-15 | 1978-05-08 | Rikagaku Kenkyusho | Novel 2-pyridone compounds and their preparation |
| JP4542743B2 (ja) * | 2002-12-26 | 2010-09-15 | Ｋｄｌ株式会社 | ピリドン誘導体の溶液状医薬組成物 |
| KR20080023680A (ko) | 2005-05-10 | 2008-03-14 | 인터뮨, 인크. | 스트레스-활성화 단백질 키나제 시스템을 조절하기 위한피리돈 유도체 |
| MX2007009796A (es) | 2007-08-14 | 2009-02-25 | Cell Therapy And Technology S | Gel conteniendo pirfenidona. |
| MX2010012848A (es) | 2008-06-03 | 2011-03-01 | Intermune Inc | Compuestos y metodos para tratar trastornos inflamatorios y fibroticos. |
| DK2670242T3 (da) * | 2011-01-31 | 2022-05-02 | Avalyn Pharma Inc | Aerosolpirfenidon- og pyridonanalogforbindelser og anvendelser deraf |
| MX2011007675A (es) | 2011-07-19 | 2012-07-11 | Cell Therapy And Technology S A De C V | Procedimiento para la fabricacion de una composicion farmaceutica en forma de tabletas de liberacion prolongada conteniendo pirfenidona y su aplicacion en la regresion de la insuficiencia renal cronica, contractura capsular mamaria y fibrosis hepatica humanas. |
| MX346763B (es) | 2012-03-28 | 2017-03-31 | Cell Therapy And Tech S A De C V | Composición tópica semisólida conteniendo pirfenidona y dialil óxido de disulfuro modificado (odd-m) para eliminar o prevenir el acné. |
| AR092742A1 (es) | 2012-10-02 | 2015-04-29 | Intermune Inc | Piridinonas antifibroticas |
| CN106459042B (zh) | 2014-04-02 | 2019-06-28 | 英特穆恩公司 | 抗纤维化吡啶酮类 |
| ITUB20154832A1 (it) * | 2015-10-29 | 2017-04-29 | Procos Spa | Processo per la sintesi di pirfenidone |
| CA3108048A1 (en) * | 2017-07-31 | 2019-02-07 | Washington University | Pirfenidone derivatives for modulation of b lymphocyte activity and organ protection |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2947755A (en) * | 1959-02-05 | 1960-08-02 | Wallace & Tiernan Inc | Substituted 1-m-aminophenyl-2-pyridones |
| US3655897A (en) * | 1971-01-25 | 1972-04-11 | Merck & Co Inc | Anti-inflammatory agents |
-
1973
- 1973-12-18 FR FR7345342A patent/FR2232316B1/fr not_active Expired
- 1973-12-18 ES ES421598A patent/ES421598A1/es not_active Expired
- 1973-12-18 JP JP14179773A patent/JPS4987677A/ja active Pending
- 1973-12-18 NL NL7317316A patent/NL7317316A/xx not_active Application Discontinuation
- 1973-12-18 DE DE19732366349 patent/DE2366349C2/de not_active Expired
- 1973-12-18 GB GB4107475A patent/GB1458049A/en not_active Expired
- 1973-12-18 DE DE19732362958 patent/DE2362958C2/de not_active Expired
- 1973-12-18 GB GB5864273A patent/GB1458048A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU6374673A (en) | 1975-06-19 |
| GB1458049A (en) | 1976-12-08 |
| FR2232316A1 (zh) | 1975-01-03 |
| JPS4987677A (zh) | 1974-08-22 |
| DE2366349C2 (de) | 1986-03-27 |
| FR2232316B1 (zh) | 1978-03-24 |
| NL7317316A (zh) | 1974-06-20 |
| DE2362958A1 (de) | 1974-06-27 |
| GB1458048A (en) | 1976-12-08 |
| DE2362958C2 (de) | 1984-06-14 |
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