ES419990A1 - Procedure for the production of isotioureas. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the production of isotioureas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES419990A1 ES419990A1 ES419990A ES419990A ES419990A1 ES 419990 A1 ES419990 A1 ES 419990A1 ES 419990 A ES419990 A ES 419990A ES 419990 A ES419990 A ES 419990A ES 419990 A1 ES419990 A1 ES 419990A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- halogen
- alkoxy
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Furan Compounds (AREA)
Abstract
Procedure for the production of isothioureas of the formula **(See formula)** in which they represent: X an alkyl radical with 1 to 6 carbon atoms, R alkyl with 1 to 12 carbon atoms, cycloalkyl with up to 8 carbon atoms, alkenyl with up to 12 carbon atoms and aralkyl (possibly substituted in the part aryl for alkyl and/or alkoxy, each with 1 to 4 carbon atoms, and/or for halogen), R1 an alkyl radical with 1 to 4 carbon atoms, R2 hydrogen or alkyl with 1 to 18 carbon atoms (optionally substituted by halogen, cyano, alkoxy with 1 to 4 carbon atoms, alkoxycarbonyl with 2 to 5 carbon atoms, phenoxy, halogenophenoxy, alkylphenoxy, alkoxyphenoxy); in addition, chloalkyl with 5 to 8 carbon atoms, aralkyl (optionally substituted by halogen, alkyl with 1 to 4 carbon atoms or alkoxy with 1 to 4 carbon atoms), aryl (optionally substituted by halogen, alkyl with 1 to 4 atoms carbon or alkoxy with 1 to 4 carbon atoms), and in addition, 1-furyl, characterized in that thioureas of the formula are reacted **(See formula)** in which X, R1 and R2 have the meanings defined above, with alkylating agents of the formula R-Y where R has the meaning indicated above and Y represents halogen, aryl sulfonate or alkyl sulfonate, in the presence of a base and a diluent. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2252691A DE2252691A1 (en) | 1972-10-27 | 1972-10-27 | AMIDOPHENYLISOTHIOURA, METHOD OF MANUFACTURING AND USE AS A MEDICINAL PRODUCT |
Publications (1)
Publication Number | Publication Date |
---|---|
ES419990A1 true ES419990A1 (en) | 1976-03-16 |
Family
ID=5860198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES419990A Expired ES419990A1 (en) | 1972-10-27 | 1973-10-26 | Procedure for the production of isotioureas. (Machine-translation by Google Translate, not legally binding) |
Country Status (23)
Country | Link |
---|---|
JP (2) | JPS4980216A (en) |
AR (1) | AR199590A1 (en) |
AT (1) | AT330199B (en) |
AU (1) | AU475884B2 (en) |
BE (1) | BE806549A (en) |
CA (1) | CA1016349A (en) |
CH (1) | CH588458A5 (en) |
CS (1) | CS165965B2 (en) |
DE (1) | DE2252691A1 (en) |
DK (1) | DK134398C (en) |
ES (1) | ES419990A1 (en) |
FR (1) | FR2204420B1 (en) |
GB (1) | GB1393329A (en) |
HU (1) | HU167555B (en) |
IE (1) | IE38427B1 (en) |
IL (1) | IL43483A (en) |
KE (1) | KE2586A (en) |
LU (1) | LU68690A1 (en) |
NL (1) | NL7314614A (en) |
PH (1) | PH10384A (en) |
PL (1) | PL91111B1 (en) |
SU (1) | SU490285A3 (en) |
ZA (1) | ZA738287B (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2434183C2 (en) * | 1974-07-16 | 1982-07-01 | Bayer Ag, 5090 Leverkusen | Substituted phenylisothioureas, a process for their preparation and their use as pharmaceuticals |
-
1972
- 1972-10-27 DE DE2252691A patent/DE2252691A1/en active Pending
-
1973
- 1973-10-23 SU SU1966532A patent/SU490285A3/en active
- 1973-10-23 AR AR250650A patent/AR199590A1/en active
- 1973-10-24 PH PH15148A patent/PH10384A/en unknown
- 1973-10-24 AU AU61768/73A patent/AU475884B2/en not_active Expired
- 1973-10-24 NL NL7314614A patent/NL7314614A/xx unknown
- 1973-10-25 LU LU68690A patent/LU68690A1/xx unknown
- 1973-10-25 AT AT904173A patent/AT330199B/en not_active IP Right Cessation
- 1973-10-25 CA CA184,274A patent/CA1016349A/en not_active Expired
- 1973-10-25 CH CH1504773A patent/CH588458A5/xx not_active IP Right Cessation
- 1973-10-25 JP JP48119502A patent/JPS4980216A/ja active Pending
- 1973-10-25 JP JP48119501A patent/JPS4976836A/ja active Pending
- 1973-10-25 IL IL43483A patent/IL43483A/en unknown
- 1973-10-26 IE IE1935/73A patent/IE38427B1/en unknown
- 1973-10-26 PL PL1973166117A patent/PL91111B1/pl unknown
- 1973-10-26 HU HUBA2989A patent/HU167555B/hu unknown
- 1973-10-26 ZA ZA738287A patent/ZA738287B/en unknown
- 1973-10-26 DK DK580973A patent/DK134398C/en active
- 1973-10-26 BE BE137089A patent/BE806549A/en unknown
- 1973-10-26 ES ES419990A patent/ES419990A1/en not_active Expired
- 1973-10-26 CS CS7387A patent/CS165965B2/cs unknown
- 1973-10-26 FR FR7338264A patent/FR2204420B1/fr not_active Expired
- 1973-10-26 GB GB4993573A patent/GB1393329A/en not_active Expired
-
1975
- 1975-12-02 KE KE2586*UA patent/KE2586A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CH588458A5 (en) | 1977-06-15 |
AT330199B (en) | 1976-06-25 |
IE38427L (en) | 1974-04-27 |
DK134398C (en) | 1977-03-28 |
KE2586A (en) | 1975-12-19 |
FR2204420B1 (en) | 1977-09-09 |
JPS4980216A (en) | 1974-08-02 |
AU475884B2 (en) | 1976-09-09 |
SU490285A3 (en) | 1975-10-30 |
PL91111B1 (en) | 1977-02-28 |
ZA738287B (en) | 1974-09-25 |
AR199590A1 (en) | 1974-09-13 |
IL43483A0 (en) | 1974-01-14 |
NL7314614A (en) | 1974-05-01 |
LU68690A1 (en) | 1974-01-08 |
CA1016349A (en) | 1977-08-30 |
IL43483A (en) | 1976-08-31 |
AU6176873A (en) | 1975-04-24 |
ATA904173A (en) | 1975-09-15 |
CS165965B2 (en) | 1975-12-22 |
HU167555B (en) | 1975-11-28 |
DK134398B (en) | 1976-11-01 |
FR2204420A1 (en) | 1974-05-24 |
GB1393329A (en) | 1975-05-07 |
DE2252691A1 (en) | 1974-05-02 |
IE38427B1 (en) | 1978-03-15 |
PH10384A (en) | 1977-03-02 |
JPS4976836A (en) | 1974-07-24 |
BE806549A (en) | 1974-04-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES427402A1 (en) | 4-(3,5-Dialkyl-4-hydroxyphenyl)-1,2-dithiole-3-thiones | |
ES387834A1 (en) | Acid amides | |
ES391491A1 (en) | Amidophenylisothioureas | |
ES419990A1 (en) | Procedure for the production of isotioureas. (Machine-translation by Google Translate, not legally binding) | |
ES398508A1 (en) | Water-soluble cationic azo pyridone dyestuffs | |
ES391492A1 (en) | Ureidophenylisothioureas | |
ES392628A2 (en) | Procedure for the obtaining of isotioureas. (Machine-translation by Google Translate, not legally binding) | |
ES406882A1 (en) | Lubricating compositions inhibited from oxidation | |
IE44614L (en) | Heterocyclylcarbonylpiperazinylquinazolines | |
ES451084A1 (en) | N,n-diethyl-4-(2,4-dinitro-6-alkylsulfonylphenylazo)-2-alkoxy-5-alkyl-carbonylaminoanilines | |
GB1331286A (en) | Diazonaphthalene compounds | |
ES324047A1 (en) | Procedure for the synthesis of 7-triacinilaminocumarinas. (Machine-translation by Google Translate, not legally binding) | |
ES396637A1 (en) | Method for preparing substituted dithiobiurets | |
ES426352A1 (en) | Trisubstituted triazine derivatives | |
ES395942A1 (en) | Quinazolone derivatives their production and their medicinal use | |
ES324901A1 (en) | A procedure for the preparation of derivatives of 2,6-diclorotiobenzamida. (Machine-translation by Google Translate, not legally binding) | |
ES334297A1 (en) | Process for preparing benzodiazepines | |
ES385015A1 (en) | Procedure for the obtaining of isotioureas. (Machine-translation by Google Translate, not legally binding) | |
ES399830A1 (en) | Procedure for the preparation of bencilo phosphonates. (Machine-translation by Google Translate, not legally binding) | |
ES389211A1 (en) | N,n-dialkyl-2-(2-(2-cycloalkylvinyl)phenoxy)alkylamines | |
ES426553A1 (en) | Procedure for preparing 2-formilquinoxalina-1.4-godosox. (Machine-translation by Google Translate, not legally binding) | |
ES334007A1 (en) | Procedure for the obtaining of sulphonic ureas. (Machine-translation by Google Translate, not legally binding) | |
ES399859A1 (en) | Procedure for the preparation of formamidines. (Machine-translation by Google Translate, not legally binding) | |
GB894125A (en) | Preparation for the combatting of nematodes | |
ES430294A1 (en) | Fast, brown sulfur dyestuffs and process for the preparation thereof |