GB1393329A - - Google Patents
Info
- Publication number
- GB1393329A GB1393329A GB4993573A GB4993573A GB1393329A GB 1393329 A GB1393329 A GB 1393329A GB 4993573 A GB4993573 A GB 4993573A GB 4993573 A GB4993573 A GB 4993573A GB 1393329 A GB1393329 A GB 1393329A
- Authority
- GB
- United Kingdom
- Prior art keywords
- carbon atoms
- radical
- radicals
- alkyl
- substituent selected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/30—Isothioureas
- C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Furan Compounds (AREA)
Abstract
1393329 Isothioureas BAYER AG 26 Oct 1973 [27 Oct 1972] 49935/73 Heading C2C The invention comprises novel compounds (I) in which X is an alkyl radical with 1 to 6 carbon atoms; R is an alkyl radical with 1 to 12 carbon atoms, or a cycloalkyl radical with up to 8 carbon atoms, or an alkenyl radical with up to 12 carbon atoms, or an aralkyl radical (optionally carrying in its aryl part at least one substituent selected from alkyl and alkoxy groups, each with 1 to 4 carbon atoms, and halogen atoms); R<SP>1</SP> is an alkyl radical with 1 to 4 carbon atoms; and R<SP>2</SP> is a hydrogen atom or an alkyl radical with 1 to 18 carbon atoms (optionally carrying at least one substituent selected from halogen and nitrile radicals, alkoxy radicals with 1 to 4 carbon atoms, alkoxycarbonyl radicals with 2 to 5 carbon atoms, and phenoxy, halophenoxy, alkylphenoxy and alkoxyphenoxy radicals), or a cycloalkyl radical with 5 to 8 carbon atoms, or an aralkyl radical (optionally carrying at least one substituent selected from halogen atoms, alkyl radicals with 1 to 4 carbon atoms, and alkoxy radicals with 1 to 4 carbon atoms), or an aryl radical (optionally carrying at least one substituent selected from halogen atoms and alkyl and alkoxy radicals with 1 to 4 carbon atoms each) or a 1-furyl radical. They are made by alkylating the corresponding thioureas. Pharmaceutical preparations showing anthelmintic action contain (I) as active ingredient; standard administration forms are described.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2252691A DE2252691A1 (en) | 1972-10-27 | 1972-10-27 | AMIDOPHENYLISOTHIOURA, METHOD OF MANUFACTURING AND USE AS A MEDICINAL PRODUCT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1393329A true GB1393329A (en) | 1975-05-07 |
Family
ID=5860198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4993573A Expired GB1393329A (en) | 1972-10-27 | 1973-10-26 |
Country Status (23)
| Country | Link |
|---|---|
| JP (2) | JPS4980216A (en) |
| AR (1) | AR199590A1 (en) |
| AT (1) | AT330199B (en) |
| AU (1) | AU475884B2 (en) |
| BE (1) | BE806549A (en) |
| CA (1) | CA1016349A (en) |
| CH (1) | CH588458A5 (en) |
| CS (1) | CS165965B2 (en) |
| DE (1) | DE2252691A1 (en) |
| DK (1) | DK134398C (en) |
| ES (1) | ES419990A1 (en) |
| FR (1) | FR2204420B1 (en) |
| GB (1) | GB1393329A (en) |
| HU (1) | HU167555B (en) |
| IE (1) | IE38427B1 (en) |
| IL (1) | IL43483A (en) |
| KE (1) | KE2586A (en) |
| LU (1) | LU68690A1 (en) |
| NL (1) | NL7314614A (en) |
| PH (1) | PH10384A (en) |
| PL (1) | PL91111B1 (en) |
| SU (1) | SU490285A3 (en) |
| ZA (1) | ZA738287B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2434183C2 (en) * | 1974-07-16 | 1982-07-01 | Bayer Ag, 5090 Leverkusen | Substituted phenylisothioureas, a process for their preparation and their use as pharmaceuticals |
-
1972
- 1972-10-27 DE DE2252691A patent/DE2252691A1/en active Pending
-
1973
- 1973-10-23 SU SU1966532A patent/SU490285A3/en active
- 1973-10-23 AR AR250650A patent/AR199590A1/en active
- 1973-10-24 PH PH15148A patent/PH10384A/en unknown
- 1973-10-24 AU AU61768/73A patent/AU475884B2/en not_active Expired
- 1973-10-24 NL NL7314614A patent/NL7314614A/xx unknown
- 1973-10-25 LU LU68690A patent/LU68690A1/xx unknown
- 1973-10-25 AT AT904173A patent/AT330199B/en not_active IP Right Cessation
- 1973-10-25 CA CA184,274A patent/CA1016349A/en not_active Expired
- 1973-10-25 CH CH1504773A patent/CH588458A5/xx not_active IP Right Cessation
- 1973-10-25 JP JP48119502A patent/JPS4980216A/ja active Pending
- 1973-10-25 JP JP48119501A patent/JPS4976836A/ja active Pending
- 1973-10-25 IL IL43483A patent/IL43483A/en unknown
- 1973-10-26 IE IE1935/73A patent/IE38427B1/en unknown
- 1973-10-26 PL PL1973166117A patent/PL91111B1/pl unknown
- 1973-10-26 HU HUBA2989A patent/HU167555B/hu unknown
- 1973-10-26 ZA ZA738287A patent/ZA738287B/en unknown
- 1973-10-26 DK DK580973A patent/DK134398C/en active
- 1973-10-26 BE BE137089A patent/BE806549A/en unknown
- 1973-10-26 ES ES419990A patent/ES419990A1/en not_active Expired
- 1973-10-26 CS CS7387A patent/CS165965B2/cs unknown
- 1973-10-26 FR FR7338264A patent/FR2204420B1/fr not_active Expired
- 1973-10-26 GB GB4993573A patent/GB1393329A/en not_active Expired
-
1975
- 1975-12-02 KE KE2586*UA patent/KE2586A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH588458A5 (en) | 1977-06-15 |
| AT330199B (en) | 1976-06-25 |
| IE38427L (en) | 1974-04-27 |
| DK134398C (en) | 1977-03-28 |
| KE2586A (en) | 1975-12-19 |
| FR2204420B1 (en) | 1977-09-09 |
| JPS4980216A (en) | 1974-08-02 |
| AU475884B2 (en) | 1976-09-09 |
| SU490285A3 (en) | 1975-10-30 |
| PL91111B1 (en) | 1977-02-28 |
| ZA738287B (en) | 1974-09-25 |
| AR199590A1 (en) | 1974-09-13 |
| IL43483A0 (en) | 1974-01-14 |
| NL7314614A (en) | 1974-05-01 |
| LU68690A1 (en) | 1974-01-08 |
| CA1016349A (en) | 1977-08-30 |
| IL43483A (en) | 1976-08-31 |
| AU6176873A (en) | 1975-04-24 |
| ATA904173A (en) | 1975-09-15 |
| ES419990A1 (en) | 1976-03-16 |
| CS165965B2 (en) | 1975-12-22 |
| HU167555B (en) | 1975-11-28 |
| DK134398B (en) | 1976-11-01 |
| FR2204420A1 (en) | 1974-05-24 |
| DE2252691A1 (en) | 1974-05-02 |
| IE38427B1 (en) | 1978-03-15 |
| PH10384A (en) | 1977-03-02 |
| JPS4976836A (en) | 1974-07-24 |
| BE806549A (en) | 1974-04-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |