IE38427L - Amidophenylisothioureas - Google Patents

Amidophenylisothioureas

Info

Publication number
IE38427L
IE38427L IE731935A IE193573A IE38427L IE 38427 L IE38427 L IE 38427L IE 731935 A IE731935 A IE 731935A IE 193573 A IE193573 A IE 193573A IE 38427 L IE38427 L IE 38427L
Authority
IE
Ireland
Prior art keywords
carbon atoms
radical
radicals
alkyl
substituent selected
Prior art date
Application number
IE731935A
Other versions
IE38427B1 (en
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of IE38427L publication Critical patent/IE38427L/en
Publication of IE38427B1 publication Critical patent/IE38427B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30—Isothioureas
    • C07C335/38—Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Abstract

1393329 Isothioureas BAYER AG 26 Oct 1973 [27 Oct 1972] 49935/73 Heading C2C The invention comprises novel compounds (I) in which X is an alkyl radical with 1 to 6 carbon atoms; R is an alkyl radical with 1 to 12 carbon atoms, or a cycloalkyl radical with up to 8 carbon atoms, or an alkenyl radical with up to 12 carbon atoms, or an aralkyl radical (optionally carrying in its aryl part at least one substituent selected from alkyl and alkoxy groups, each with 1 to 4 carbon atoms, and halogen atoms); R<SP>1</SP> is an alkyl radical with 1 to 4 carbon atoms; and R<SP>2</SP> is a hydrogen atom or an alkyl radical with 1 to 18 carbon atoms (optionally carrying at least one substituent selected from halogen and nitrile radicals, alkoxy radicals with 1 to 4 carbon atoms, alkoxycarbonyl radicals with 2 to 5 carbon atoms, and phenoxy, halophenoxy, alkylphenoxy and alkoxyphenoxy radicals), or a cycloalkyl radical with 5 to 8 carbon atoms, or an aralkyl radical (optionally carrying at least one substituent selected from halogen atoms, alkyl radicals with 1 to 4 carbon atoms, and alkoxy radicals with 1 to 4 carbon atoms), or an aryl radical (optionally carrying at least one substituent selected from halogen atoms and alkyl and alkoxy radicals with 1 to 4 carbon atoms each) or a 1-furyl radical. They are made by alkylating the corresponding thioureas. Pharmaceutical preparations showing anthelmintic action contain (I) as active ingredient; standard administration forms are described. [GB1393329A]
IE1935/73A 1972-10-27 1973-10-26 New amidophenylisothioureas their procuction and their medicinal use IE38427B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2252691A DE2252691A1 (en) 1972-10-27 1972-10-27 AMIDOPHENYLISOTHIOURA, METHOD OF MANUFACTURING AND USE AS A MEDICINAL PRODUCT

Publications (2)

Publication Number Publication Date
IE38427L true IE38427L (en) 1974-04-27
IE38427B1 IE38427B1 (en) 1978-03-15

Family

ID=5860198

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1935/73A IE38427B1 (en) 1972-10-27 1973-10-26 New amidophenylisothioureas their procuction and their medicinal use

Country Status (23)

Country Link
JP (2) JPS4976836A (en)
AR (1) AR199590A1 (en)
AT (1) AT330199B (en)
AU (1) AU475884B2 (en)
BE (1) BE806549A (en)
CA (1) CA1016349A (en)
CH (1) CH588458A5 (en)
CS (1) CS165965B2 (en)
DE (1) DE2252691A1 (en)
DK (1) DK134398C (en)
ES (1) ES419990A1 (en)
FR (1) FR2204420B1 (en)
GB (1) GB1393329A (en)
HU (1) HU167555B (en)
IE (1) IE38427B1 (en)
IL (1) IL43483A (en)
KE (1) KE2586A (en)
LU (1) LU68690A1 (en)
NL (1) NL7314614A (en)
PH (1) PH10384A (en)
PL (1) PL91111B1 (en)
SU (1) SU490285A3 (en)
ZA (1) ZA738287B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2434183C2 (en) * 1974-07-16 1982-07-01 Bayer Ag, 5090 Leverkusen Substituted phenylisothioureas, a process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
JPS4976836A (en) 1974-07-24
KE2586A (en) 1975-12-19
DE2252691A1 (en) 1974-05-02
FR2204420B1 (en) 1977-09-09
ZA738287B (en) 1974-09-25
DK134398C (en) 1977-03-28
NL7314614A (en) 1974-05-01
IL43483A (en) 1976-08-31
SU490285A3 (en) 1975-10-30
CA1016349A (en) 1977-08-30
IL43483A0 (en) 1974-01-14
LU68690A1 (en) 1974-01-08
AT330199B (en) 1976-06-25
AU475884B2 (en) 1976-09-09
ES419990A1 (en) 1976-03-16
GB1393329A (en) 1975-05-07
PL91111B1 (en) 1977-02-28
HU167555B (en) 1975-11-28
JPS4980216A (en) 1974-08-02
BE806549A (en) 1974-04-26
FR2204420A1 (en) 1974-05-24
CS165965B2 (en) 1975-12-22
DK134398B (en) 1976-11-01
AU6176873A (en) 1975-04-24
IE38427B1 (en) 1978-03-15
CH588458A5 (en) 1977-06-15
PH10384A (en) 1977-03-02
AR199590A1 (en) 1974-09-13
ATA904173A (en) 1975-09-15

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