ES389211A1 - N,n-dialkyl-2-(2-(2-cycloalkylvinyl)phenoxy)alkylamines - Google Patents

N,n-dialkyl-2-(2-(2-cycloalkylvinyl)phenoxy)alkylamines

Info

Publication number
ES389211A1
ES389211A1 ES389211A ES389211A ES389211A1 ES 389211 A1 ES389211 A1 ES 389211A1 ES 389211 A ES389211 A ES 389211A ES 389211 A ES389211 A ES 389211A ES 389211 A1 ES389211 A1 ES 389211A1
Authority
ES
Spain
Prior art keywords
formula
group
carbon atoms
compound
aliphatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES389211A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp
Original Assignee
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp filed Critical Pfizer Corp
Publication of ES389211A1 publication Critical patent/ES389211A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

Abstract

Procedure for obtaining ortho-substituted phenoxy-amines, of general formula: ** (See formula) ** wherein R1 represents an aliphatic, aliphatic, saturated hydrocarbon radical containing at least 5 carbon atoms and preferably from 5 to 8 carbon atoms; Y represents either (a) an aminoalkyl group of the formula -Alk-NR2 R3, in which R2 and R3 each represent a lower alkyl group, or together with the nitrogen atom to which they are attached, form a saturated heterocyclic group and "Alk" represents an aliphatic, saturated hydrocarbon group containing from 2 to 4 carbon atoms, the free valences being located at different carbon atoms; or (B) an amino-cyclic group of the formula (see formula) in which n is 0 to 3 and Z is a group containing at least one nitrogen atom and at least 4 carbon atoms, with any of said nitrogen atoms being separated from the oxygen atom, to which it is attached the amino-cyclic group, through a chain of 2 to 4 carbon atoms; y represents a hydrogen, or halogen atom or a lower alkyl or lower alkoxy group; characterized by comprising converting an ortho-acylphenol of formula: ** (See formula) ** to a compound of formula: ** (See formula) ** reducing the carbonyl group of the compound of formula (VIII) to a carbinol group thereby forming a compound of formula: ** (See formula) ** and converting the compound of formula (VAT) to the desired compound of formula I. (Machine-translation by Google Translate, not legally binding)
ES389211A 1970-03-13 1971-03-13 N,n-dialkyl-2-(2-(2-cycloalkylvinyl)phenoxy)alkylamines Expired ES389211A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB02111/70A GB1283451A (en) 1970-03-13 1970-03-13 Ortho-substituted phenol ethers, their preparation and compositions containing them

Publications (1)

Publication Number Publication Date
ES389211A1 true ES389211A1 (en) 1973-06-16

Family

ID=9998576

Family Applications (2)

Application Number Title Priority Date Filing Date
ES389210A Expired ES389210A1 (en) 1970-03-13 1971-03-13 N,n-dialkyl-2-(2-(2-cycloalkylvinyl)phenoxy)alkylamines
ES389211A Expired ES389211A1 (en) 1970-03-13 1971-03-13 N,n-dialkyl-2-(2-(2-cycloalkylvinyl)phenoxy)alkylamines

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES389210A Expired ES389210A1 (en) 1970-03-13 1971-03-13 N,n-dialkyl-2-(2-(2-cycloalkylvinyl)phenoxy)alkylamines

Country Status (7)

Country Link
US (1) US3751470A (en)
JP (1) JPS5214B1 (en)
BE (1) BE763744A (en)
DE (1) DE2109941A1 (en)
ES (2) ES389210A1 (en)
FR (1) FR2085705B1 (en)
GB (1) GB1283451A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910896A (en) * 1970-03-13 1975-10-07 Pfizer Substituted phenoxyalkylamines as gastric anti-secretory agents
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Also Published As

Publication number Publication date
ES389210A1 (en) 1973-06-01
FR2085705A1 (en) 1971-12-31
FR2085705B1 (en) 1974-08-30
GB1283451A (en) 1972-07-26
JPS5214B1 (en) 1977-01-05
US3751470A (en) 1973-08-07
BE763744A (en) 1971-09-03
DE2109941A1 (en) 1971-11-25

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