ES392628A2 - Procedure for the obtaining of isotioureas. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of isotioureas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES392628A2
ES392628A2 ES392628A ES392628A ES392628A2 ES 392628 A2 ES392628 A2 ES 392628A2 ES 392628 A ES392628 A ES 392628A ES 392628 A ES392628 A ES 392628A ES 392628 A2 ES392628 A2 ES 392628A2
Authority
ES
Spain
Prior art keywords
translation
procedure
obtaining
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES392628A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Publication of ES392628A2 publication Critical patent/ES392628A2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Tires In General (AREA)

Abstract

Improvements introduced in the object of the main patent nº 385.015, presented on october 29, 1970, by: procedure for obtaining isothioureas, of general formula: ** (see formula) ** Wherein a is such that, together with carbon and nitrogen, it forms an unsaturated heterocyclic basic nucleus having 5 or 6 atoms; x is hydrogen, lower alkyl, halogen or lower alkylthio; n is from 3 to 6; and r is lower alkyl or substituted or unsubstituted aroyl, or aralkyl but not benzyl; characterized in that an amine of general formula: ** (see formula) ** Is reacted with an isothiocyanate of formula rncs, symbols a, x, n and r being defined as above. (Machine-translation by Google Translate, not legally binding)
ES392628A 1970-06-25 1971-06-25 Procedure for the obtaining of isotioureas. (Machine-translation by Google Translate, not legally binding) Expired ES392628A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB3083470 1970-06-25
GB4900770 1970-10-15
GB291871 1971-01-22

Publications (1)

Publication Number Publication Date
ES392628A2 true ES392628A2 (en) 1975-07-16

Family

ID=27254147

Family Applications (1)

Application Number Title Priority Date Filing Date
ES392628A Expired ES392628A2 (en) 1970-06-25 1971-06-25 Procedure for the obtaining of isotioureas. (Machine-translation by Google Translate, not legally binding)

Country Status (13)

Country Link
JP (1) JPS5738583B1 (en)
BE (1) BE768474A (en)
CA (1) CA938556A (en)
CH (1) CH551409A (en)
DE (1) DE2131625A1 (en)
ES (1) ES392628A2 (en)
FR (1) FR2100822A1 (en)
HK (1) HK55076A (en)
IE (1) IE35505B1 (en)
IL (1) IL36980A (en)
KE (1) KE2624A (en)
NL (1) NL7108585A (en)
PH (1) PH11791A (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565647A (en) * 1975-07-31 1980-04-23 Smith Kline French Lab Pharmacologically active compounds 4-substituted-imidazole-5-methanols
DE3107599C2 (en) * 1981-02-27 1982-12-16 Ludwig Heumann & Co GmbH, 8500 Nürnberg N-cyano-N'-methyl-N "- {2 - [(5-methylthio-imidazol-4-yl) -methylthio] -ethyl} -guanidine, process for its preparation and medicaments containing this compound
FR2686084B1 (en) * 1992-01-10 1995-12-22 Bioprojet Soc Civ NEW IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATIONS.
USRE37303E1 (en) * 1992-01-10 2001-07-31 Institut National Del La Sante Et De La Recherche Medicale Imidazole compounds and their therapeutic applications
NL9302045A (en) * 1993-08-27 1995-03-16 Vrije Universiteit New imidazole derivative with agonistic or antagonistic activity on the histamine H3 receptor
AU7823894A (en) * 1993-08-27 1995-03-21 Vrije Universiteit New imidazole derivatives having agonistic or antagonistic activity on the histamine h3 receptor

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE758145A (en) * 1969-10-29 1971-04-28 Smith Kline French Lab ISO-THIO-UREES AND DERIVATIVES

Also Published As

Publication number Publication date
FR2100822B1 (en) 1974-11-15
JPS5738583B1 (en) 1982-08-16
CH551409A (en) 1974-07-15
PH11791A (en) 1978-07-05
NL7108585A (en) 1971-12-28
FR2100822A1 (en) 1972-03-24
IE35505B1 (en) 1976-03-03
HK55076A (en) 1976-09-17
DE2131625A1 (en) 1971-12-30
IL36980A (en) 1978-07-31
BE768474A (en) 1971-12-14
KE2624A (en) 1976-05-28
IL36980A0 (en) 1971-08-25
CA938556A (en) 1973-12-18
IE35505L (en) 1971-12-25

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Legal Events

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Effective date: 20170703