ES418687A1 - Basic ethers and preparation thereof - Google Patents
Basic ethers and preparation thereofInfo
- Publication number
- ES418687A1 ES418687A1 ES418687A ES418687A ES418687A1 ES 418687 A1 ES418687 A1 ES 418687A1 ES 418687 A ES418687 A ES 418687A ES 418687 A ES418687 A ES 418687A ES 418687 A1 ES418687 A1 ES 418687A1
- Authority
- ES
- Spain
- Prior art keywords
- moiety
- residues
- salts
- formula
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for obtaining basic ethers, of general formula **(See formula)** where R is an alkyl group with a maximum of 4 carbon atoms, R1 is hydrogen, a lower alkyl radical, an allyl radical or a benzyl radical, R2 is an alkenyl, aralkenyl, haloalkenyl, alkynyl, cycloalkyl or methyl alkyl group and R3 means hydrogen or a methyl group or its salts, characterized in that compounds of the general formula **(See formula)** in which R and R, have the definition indicated for formula I and X means the residues (see formula) or -N = CH-R5, where R4 represents a lower alkyl moiety, an allyl moiety, a benzyl moiety or an acyl moiety dissociable hydrolytically and R5 is an aryl moiety, if substituted, are reacted with halides of general formula Hal - CH2 - R2 III wherein Hal signifies a halogen atom and R2 has the meaning defined above, after which CH-R5 groups or R4 residues with acyl meaning existing in the reaction product are dissociated by alkaline or acid treatment and the residues R1 with the meaning of hydrogen, if appropriate, are exchanged for an alkyl or benzyl residue or, in the case that the residue means -CH2-R2 is exchanged for another allyl residue, after which the obtained bases are transformed in salts or the bases are released from the salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT776472A AT319916B (en) | 1972-09-11 | 1972-09-11 | Process for the production of new basic ethers |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES418687A1 true ES418687A1 (en) | 1976-02-16 |
Family
ID=3599253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES418687A Expired ES418687A1 (en) | 1972-09-11 | 1973-09-11 | Basic ethers and preparation thereof |
Country Status (18)
| Country | Link |
|---|---|
| JP (1) | JPS5320033B2 (en) |
| AT (1) | AT319916B (en) |
| BE (1) | BE804692A (en) |
| CA (1) | CA986138A (en) |
| CH (2) | CH590206A5 (en) |
| CS (1) | CS203904B2 (en) |
| DD (1) | DD108521A1 (en) |
| ES (1) | ES418687A1 (en) |
| FI (1) | FI56826C (en) |
| FR (1) | FR2198740B1 (en) |
| GB (1) | GB1377350A (en) |
| HU (1) | HU166685B (en) |
| LU (1) | LU68308A1 (en) |
| PL (2) | PL86974B1 (en) |
| RO (2) | RO63980A (en) |
| SE (1) | SE413892B (en) |
| SU (1) | SU495825A3 (en) |
| ZA (1) | ZA737200B (en) |
-
1972
- 1972-09-11 AT AT776472A patent/AT319916B/en not_active IP Right Cessation
-
1973
- 1973-08-24 FR FR7330701A patent/FR2198740B1/fr not_active Expired
- 1973-08-27 LU LU68308A patent/LU68308A1/xx unknown
- 1973-08-29 FI FI2684/73A patent/FI56826C/en active
- 1973-09-04 HU HUCE962A patent/HU166685B/hu unknown
- 1973-09-06 CA CA180,396A patent/CA986138A/en not_active Expired
- 1973-09-06 GB GB4206373A patent/GB1377350A/en not_active Expired
- 1973-09-10 CH CH835576A patent/CH590206A5/xx not_active IP Right Cessation
- 1973-09-10 ZA ZA737200*A patent/ZA737200B/en unknown
- 1973-09-10 PL PL1973165129A patent/PL86974B1/en unknown
- 1973-09-10 DD DD173374A patent/DD108521A1/xx unknown
- 1973-09-10 CH CH1294973A patent/CH596144A5/xx not_active IP Right Cessation
- 1973-09-10 BE BE135522A patent/BE804692A/en unknown
- 1973-09-10 PL PL1973183330A patent/PL92115B1/en unknown
- 1973-09-10 SU SU1957929A patent/SU495825A3/en active
- 1973-09-10 SE SE7312280A patent/SE413892B/en unknown
- 1973-09-11 ES ES418687A patent/ES418687A1/en not_active Expired
- 1973-09-11 RO RO7300076047A patent/RO63980A/en unknown
- 1973-09-11 CS CS736291A patent/CS203904B2/en unknown
- 1973-09-11 RO RO7384229A patent/RO68417A/en unknown
- 1973-09-11 JP JP10176373A patent/JPS5320033B2/ja not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE413892B (en) | 1980-06-30 |
| FI56826C (en) | 1980-04-10 |
| FI56826B (en) | 1979-12-31 |
| SU495825A3 (en) | 1975-12-15 |
| CH590206A5 (en) | 1977-07-29 |
| LU68308A1 (en) | 1973-11-23 |
| PL86974B1 (en) | 1976-06-30 |
| HU166685B (en) | 1975-05-28 |
| ZA737200B (en) | 1974-08-28 |
| RO63980A (en) | 1978-08-15 |
| BE804692A (en) | 1974-03-11 |
| DD108521A1 (en) | 1974-09-20 |
| GB1377350A (en) | 1974-12-11 |
| FR2198740B1 (en) | 1977-01-14 |
| AT319916B (en) | 1975-01-10 |
| CA986138A (en) | 1976-03-23 |
| CH596144A5 (en) | 1978-02-28 |
| RO68417A (en) | 1981-09-24 |
| CS203904B2 (en) | 1981-03-31 |
| JPS5320033B2 (en) | 1978-06-24 |
| AU6018473A (en) | 1975-03-13 |
| JPS4962452A (en) | 1974-06-17 |
| PL92115B1 (en) | 1977-03-31 |
| FR2198740A1 (en) | 1974-04-05 |
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