ES308038A1 - A procedure for the production of 5-phenyl-1,4-3h-benzodiazepin-2 (1H) -onas. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the production of 5-phenyl-1,4-3h-benzodiazepin-2 (1H) -onas. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES308038A1
ES308038A1 ES0308038A ES308038A ES308038A1 ES 308038 A1 ES308038 A1 ES 308038A1 ES 0308038 A ES0308038 A ES 0308038A ES 308038 A ES308038 A ES 308038A ES 308038 A1 ES308038 A1 ES 308038A1
Authority
ES
Spain
Prior art keywords
group
benzodiazepin
translation
phenyl
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0308038A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delmar Chemicals Inc
Original Assignee
Delmar Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delmar Chemicals Inc filed Critical Delmar Chemicals Inc
Publication of ES308038A1 publication Critical patent/ES308038A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A process for the production of 5-phenyl-1,4-3H-benzodiazepin-2 (1H) -ones of the general formula ** (See formula) ** wherein R 1 represents hydrogen, a methyl group or an ethyl group, R 2 and R 3 represent a hydrogen atom, a methyl group, a halogenomethyl group, a methoxyl group or a halogen, and R 4 represents hydrogen, a lower alkyl group, a aryl group or an aralkyl group containing 1-2 carbon atoms in the alkyl unit, which comprises the treatment of a 2-phthalimido-acylamido-benzophenone represented by the general formula ** (See formula) ** wherein R1, R2, R3 and R4 have the meaning indicated above, by heating said 2-phthalimido-acylamido-benzophenone with at least about 2 molar equivalent of hydrazine hydrate. (Machine-translation by Google Translate, not legally binding)
ES0308038A 1964-01-14 1965-01-12 A procedure for the production of 5-phenyl-1,4-3h-benzodiazepin-2 (1H) -onas. (Machine-translation by Google Translate, not legally binding) Expired ES308038A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB169264A GB1063891A (en) 1964-01-14 1964-01-14 Method for preparation of benzodiazepinones
GB169364A GB1056289A (en) 1964-01-14 1964-01-14 2-phthalimido acetamido benzophenones and their preparation

Publications (1)

Publication Number Publication Date
ES308038A1 true ES308038A1 (en) 1965-06-16

Family

ID=26236912

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0308038A Expired ES308038A1 (en) 1964-01-14 1965-01-12 A procedure for the production of 5-phenyl-1,4-3h-benzodiazepin-2 (1H) -onas. (Machine-translation by Google Translate, not legally binding)

Country Status (12)

Country Link
CH (2) CH450418A (en)
CY (1) CY532A (en)
DE (1) DE1545724B2 (en)
DK (1) DK138494B (en)
ES (1) ES308038A1 (en)
FI (1) FI47104C (en)
GB (2) GB1063891A (en)
IL (1) IL22679A (en)
MY (1) MY7000102A (en)
NL (2) NL6500446A (en)
NO (1) NO119797B (en)
SE (2) SE320377B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH602672A5 (en) * 1974-06-28 1978-07-31 Hoffmann La Roche
IT1087017B (en) * 1977-10-18 1985-05-31 Ravizza Spa PROCESS FOR THE PREPARATION OF A 7-CHLORO-5- (2-CHLOROPHENYL) -BENZODIAZE PINONE
CA1332410C (en) * 1984-06-26 1994-10-11 Roger M. Freidinger Benzodiazepine analogs
US4820834A (en) * 1984-06-26 1989-04-11 Merck & Co., Inc. Benzodiazepine analogs
US5004741A (en) * 1984-06-26 1991-04-02 Merck & Co., Inc. Methods of antagonizing CCK or gastrin with benzodiazepine analogs

Also Published As

Publication number Publication date
DK138494B (en) 1978-09-18
GB1063891A (en) 1967-04-05
FI47104B (en) 1973-05-31
DE1545724B2 (en) 1977-02-10
FI47104C (en) 1973-09-10
SE363104B (en) 1974-01-07
DK138494C (en) 1979-02-26
CY532A (en) 1970-03-23
NL7017982A (en) 1971-03-25
MY7000102A (en) 1970-12-31
NO119797B (en) 1970-07-06
CH459240A (en) 1968-07-15
SE320377B (en) 1970-02-09
IL22679A (en) 1968-09-26
NL6500446A (en) 1965-07-15
GB1056289A (en) 1967-01-25
DE1545724A1 (en) 1969-10-09
CH450418A (en) 1968-01-31

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