ES432566A1 - Tri-iodo benzene derivatives and their use as x-ray contrast - Google Patents
Tri-iodo benzene derivatives and their use as x-ray contrastInfo
- Publication number
- ES432566A1 ES432566A1 ES432566A ES432566A ES432566A1 ES 432566 A1 ES432566 A1 ES 432566A1 ES 432566 A ES432566 A ES 432566A ES 432566 A ES432566 A ES 432566A ES 432566 A1 ES432566 A1 ES 432566A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- radical
- see
- compound
- benzene derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
- A61K49/0433—X-ray contrast preparations containing an organic halogenated X-ray contrast-enhancing agent
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Abstract
Preparation process for iodinated benzene derivatives, and more particularly for compounds of the general formula: ** (See formula) ** in which R1 is a hydrogen atom or a lower alkoyl radical, R2 is a radical of formula ** (See formula) ** wherein R4 and R5 are, independently of each other, a hydrogen atom, a lower alkoxy radical or a lower hydroxyalkyl radical and R3 is a radical of formula ** (See formula) ** in which R6 and R7 have the significance given for R4 and R5 or of formula ** (See formula) ** in which R7 is a hydrogen atom or a lower alkoxy radical and R8 is a lower alkoyl radical, characterized in that a hydroxylated acid halide of the formula is reacted Hal - Co - (CHOH) 5H on an amine of formula ** (See formula) ** in which R2 and R3 have the meanings given above, thus obtaining a compound of formula I in which R1 is hydrogen and to obtain a compound of formula I in which R1 is a lower alkoxy radical, an alkylation of a compound of formula I in which R1 is hydrogen. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5683173A GB1436357A (en) | 1973-12-07 | 1973-12-07 | Tri-iodo benzene derivatives and their use as x-ray contrast |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES432566A1 true ES432566A1 (en) | 1976-11-01 |
Family
ID=10477658
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES432566A Expired ES432566A1 (en) | 1973-12-07 | 1974-12-04 | Tri-iodo benzene derivatives and their use as x-ray contrast |
Country Status (10)
| Country | Link |
|---|---|
| BE (1) | BE823029A (en) |
| BR (1) | BR7410247A (en) |
| CH (1) | CH593916A5 (en) |
| DK (1) | DK137311B (en) |
| ES (1) | ES432566A1 (en) |
| FR (1) | FR2253509B1 (en) |
| GB (1) | GB1436357A (en) |
| NL (1) | NL7415951A (en) |
| NO (1) | NO139128C (en) |
| SE (1) | SE410966B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4125709A (en) * | 1974-10-04 | 1978-11-14 | Mallinckrodt, Inc. | Polyhydroxy-alkyl-3,5-disubstituted-2,4,6-triiodocarbanilates |
| GB1491129A (en) * | 1975-06-04 | 1977-11-09 | Guerbet Sa | Iodo-benzene derivatives and an x-ray contrast medium containing them |
| DE2909439A1 (en) | 1979-03-08 | 1980-09-18 | Schering Ag | NEW NON-ionic x-ray contrast agents |
| FR2512014A1 (en) * | 1981-08-28 | 1983-03-04 | Guerbet Sa | BROMINATED COMPOUNDS FOR USE IN OPACIFYING PRODUCTS |
| FR2511871A1 (en) * | 1981-08-28 | 1983-03-04 | Guerbet Sa | PROCESS FOR INCREASING THE TOLERANCE OF OPACIFYING PRODUCTS AND OPACIFYING PRODUCTS THUS OBTAINED |
-
1973
- 1973-12-07 GB GB5683173A patent/GB1436357A/en not_active Expired
-
1974
- 1974-11-21 CH CH1548874A patent/CH593916A5/xx not_active IP Right Cessation
- 1974-11-21 FR FR7438334A patent/FR2253509B1/fr not_active Expired
- 1974-12-02 SE SE7415042A patent/SE410966B/en unknown
- 1974-12-04 DK DK630974AA patent/DK137311B/en not_active IP Right Cessation
- 1974-12-04 ES ES432566A patent/ES432566A1/en not_active Expired
- 1974-12-05 NO NO744400A patent/NO139128C/en unknown
- 1974-12-06 NL NL7415951A patent/NL7415951A/en not_active Application Discontinuation
- 1974-12-06 BE BE151223A patent/BE823029A/en not_active IP Right Cessation
- 1974-12-06 BR BR10247/74A patent/BR7410247A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE410966B (en) | 1979-11-19 |
| DK630974A (en) | 1975-07-21 |
| CH593916A5 (en) | 1977-12-30 |
| NO139128C (en) | 1979-01-31 |
| BE823029A (en) | 1975-06-06 |
| BR7410247A (en) | 1976-06-29 |
| DK137311C (en) | 1978-07-17 |
| FR2253509B1 (en) | 1979-08-10 |
| DK137311B (en) | 1978-02-20 |
| DE2456685A1 (en) | 1975-06-12 |
| GB1436357A (en) | 1976-05-19 |
| FR2253509A1 (en) | 1975-07-04 |
| DE2456685B2 (en) | 1976-02-26 |
| SE7415042L (en) | 1975-06-09 |
| NO744400L (en) | 1975-07-07 |
| NL7415951A (en) | 1975-06-10 |
| NO139128B (en) | 1978-10-02 |
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