ES415144A1 - Un procedimiento para la preparacion de nuevos derivados de5h-dibenzo (a,d) cicloheptenos. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de5h-dibenzo (a,d) cicloheptenos.Info
- Publication number
- ES415144A1 ES415144A1 ES415144A ES415144A ES415144A1 ES 415144 A1 ES415144 A1 ES 415144A1 ES 415144 A ES415144 A ES 415144A ES 415144 A ES415144 A ES 415144A ES 415144 A1 ES415144 A1 ES 415144A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- group
- lower alkyl
- see
- nitrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000543 intermediate Substances 0.000 title 1
- 239000002831 pharmacologic agent Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 229910052757 nitrogen Inorganic materials 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- XAKBSHICSHRJCL-UHFFFAOYSA-N [CH2]C(=O)C1=CC=CC=C1 Chemical group [CH2]C(=O)C1=CC=CC=C1 XAKBSHICSHRJCL-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000000623 heterocyclic group Chemical group 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000001933 cycloheptenes Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- -1 hydroxyalkoxyalkyl Chemical group 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 229910052760 oxygen Chemical group 0.000 abstract 1
- 239000001301 oxygen Chemical group 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 125000001889 triflyl group Chemical group FC(F)(F)S(*)(=O)=O 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US00256751A US3828034A (en) | 1972-05-25 | 1972-05-25 | Tricyclic pharmacological agents,intermediates and methods of making |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES415144A1 true ES415144A1 (es) | 1976-06-16 |
Family
ID=22973451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES415144A Expired ES415144A1 (es) | 1972-05-25 | 1973-05-24 | Un procedimiento para la preparacion de nuevos derivados de5h-dibenzo (a,d) cicloheptenos. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3828034A (enExample) |
| AT (1) | AT327873B (enExample) |
| BE (1) | BE800037A (enExample) |
| DE (1) | DE2326401A1 (enExample) |
| ES (1) | ES415144A1 (enExample) |
| FR (1) | FR2185413B1 (enExample) |
| GB (1) | GB1427404A (enExample) |
| IL (1) | IL42207A (enExample) |
| NL (1) | NL7307010A (enExample) |
| ZA (1) | ZA733021B (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3965181A (en) * | 1973-07-06 | 1976-06-22 | Syntex (U.S.A.) Inc. | Tricyclic pharmacological agents, intermediates and methods of making |
| DE69127549T2 (de) * | 1990-05-18 | 1998-04-23 | Merrell Pharma Inc | 5h-dibenzo[a,d]cycloheptene als muscarinic-rezeptor-antagonist |
| US5508280A (en) * | 1990-05-18 | 1996-04-16 | Merrell Pharmaceuticals, Inc. | 5H-Dibenzo (A,D) cycloheptenes as muscarinic receptor antagonists |
| IL129122A0 (en) * | 1996-10-04 | 2000-02-17 | Novo Nordisk As | N-substituted azaheterocyclic compounds |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3309404A (en) * | 1962-04-04 | 1967-03-14 | Merck & Co Inc | Derivatives of dibenzocycloheptenes and a process for their preparation |
| FR1476483A (fr) * | 1965-05-03 | 1967-04-07 | Merck & Co Inc | Fabrication de dibenzocycloheptènes substitués |
-
1972
- 1972-05-25 US US00256751A patent/US3828034A/en not_active Expired - Lifetime
-
1973
- 1973-05-03 ZA ZA733021A patent/ZA733021B/xx unknown
- 1973-05-04 IL IL42207A patent/IL42207A/en unknown
- 1973-05-16 GB GB2343673A patent/GB1427404A/en not_active Expired
- 1973-05-18 NL NL7307010A patent/NL7307010A/xx unknown
- 1973-05-24 AT AT454573A patent/AT327873B/de active
- 1973-05-24 DE DE2326401A patent/DE2326401A1/de active Pending
- 1973-05-24 FR FR7318978A patent/FR2185413B1/fr not_active Expired
- 1973-05-24 ES ES415144A patent/ES415144A1/es not_active Expired
- 1973-05-25 BE BE131520A patent/BE800037A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATA454573A (de) | 1975-05-15 |
| FR2185413B1 (enExample) | 1976-10-22 |
| GB1427404A (en) | 1976-03-10 |
| IL42207A0 (en) | 1973-07-30 |
| NL7307010A (enExample) | 1973-11-27 |
| BE800037A (fr) | 1973-11-26 |
| IL42207A (en) | 1977-03-31 |
| ZA733021B (en) | 1974-12-24 |
| DE2326401A1 (de) | 1973-12-06 |
| AT327873B (de) | 1976-02-25 |
| AU5579873A (en) | 1974-11-21 |
| FR2185413A1 (enExample) | 1974-01-04 |
| US3828034A (en) | 1974-08-06 |
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