ES413056A1 - 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity - Google Patents

4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Info

Publication number
ES413056A1
ES413056A1 ES413056A ES413056A ES413056A1 ES 413056 A1 ES413056 A1 ES 413056A1 ES 413056 A ES413056 A ES 413056A ES 413056 A ES413056 A ES 413056A ES 413056 A1 ES413056 A1 ES 413056A1
Authority
ES
Spain
Prior art keywords
hydroxybutyramide
derivs
biphenylyl
substd
opt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES413056A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES413056A1 publication Critical patent/ES413056A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Title cpds. are of formula (I): (where R1 is H, halogen, CN, NO2 or amino R2 is H or halogen, and R3 and R4 are H, 1-5C alkyl (opt. substd. by lower alkoxy or OH) or phenyl (opt. substd. by a halogen atom or CF3, OH or lower alkyl or alkoxy gp.), or NR3R4 is pyrrolidino, piperidino, morpholino or piperazino opt. substd. by lower alkyl) and physiologically tolerable salts with acids of those cpds. which are basic.
ES413056A 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity Expired ES413056A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2141926A DE2141926A1 (en) 1971-08-20 1971-08-20 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Publications (1)

Publication Number Publication Date
ES413056A1 true ES413056A1 (en) 1976-01-16

Family

ID=5817372

Family Applications (5)

Application Number Title Priority Date Filing Date
ES405945A Expired ES405945A1 (en) 1971-08-20 1972-08-18 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413056A Expired ES413056A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413055A Expired ES413055A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413054A Expired ES413054A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413053A Expired ES413053A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES405945A Expired ES405945A1 (en) 1971-08-20 1972-08-18 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES413055A Expired ES413055A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413054A Expired ES413054A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413053A Expired ES413053A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Country Status (9)

Country Link
JP (1) JPS4829747A (en)
AT (2) ATA785273A (en)
BG (3) BG20103A3 (en)
DD (1) DD101146A5 (en)
DE (1) DE2141926A1 (en)
ES (5) ES405945A1 (en)
HU (1) HU163805B (en)
PL (1) PL79512B1 (en)
SU (1) SU481151A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5178462A (en) * 1974-12-28 1976-07-08 Uragami Riko Kk Suchiimano chusuisochi
FR2817256B1 (en) * 2000-11-27 2005-07-15 Univ Pasteur DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND ITS SUPERIOR APPROACHES AS GAMMA-HYDROXYBUTYRATE (GHB) RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES

Also Published As

Publication number Publication date
BG20103A3 (en) 1975-10-30
PL79512B1 (en) 1975-06-30
BG19795A3 (en) 1975-10-10
ES413053A1 (en) 1976-01-16
AT319921B (en) 1975-01-10
SU481151A3 (en) 1975-08-15
ATA785273A (en) 1975-01-15
JPS4829747A (en) 1973-04-19
DE2141926A1 (en) 1973-03-01
DD101146A5 (en) 1973-10-20
HU163805B (en) 1973-10-27
ES413054A1 (en) 1976-01-16
BG20102A3 (en) 1975-10-30
ES405945A1 (en) 1975-09-16
ES413055A1 (en) 1976-01-16

Similar Documents

Publication Publication Date Title
ES376051A1 (en) Lower alkyl esters of p-benzoylphenoxy isobutyric acid
ES413053A1 (en) 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES405946A1 (en) 4-(4-biphenylyl)-butyramide derivs - with antiphlogistic activity
FR2047882A1 (en) Analgesic antiinflammatory 4-(2-alkoxy - phenylamino-quinolines and intermediates
ES410836A1 (en) 4-(4-biphenylyl)-4-oxobutyramides - with antiphlogistic activity
FR2166101A1 (en) 1,4-di (morpholino,piperidino or pyrrolidino)-7-substd - -pyrido (3,4-d)-pyridazines - as diuretics
FR2258840A1 (en) (4-Phenylpiperazino) alkyl esters - with analgesic activity for human and veterinary use
NL7900613A (en) Phenoxyacetic acid derivs
ES394969A1 (en) 5-(2-amino-alkoxy-phenoxy-methyl)-3-alkyl-isoxazoles - useful as hypotensives and sedatives
FR2126455A1 (en) Prostanoic acid derivs - with luteolytic, hypotensive and bronchodilator activity
FR2175040A1 (en) Vincaminic acid amines - cerebral microcirculatory active
FR2118932A1 (en) 2-oxo-1, 2, 3, 4-tetrahydroquinazoline derivs - sedatives antiinflammatories, analgesics, uricosurics and antimicrobials
FR2261005A1 (en) 5-Amino-indane-1-carboxylic acid derivs - prepd. by hydrolysis of their lower-alkyl esters
FR2152345A1 (en) Alpha-(2-thiazolyl)oxyalkanoic acids and derivatives - - with analgesic,antiinflammatory and antipyretic activity
FR2145601A1 (en) Prostaglandin analogues - with gastric secretion inhibiting bronchodilatory, hypotensive etc activity
ES435568A1 (en) Disubstituted xanthone carboxylic acid compounds
FR2164520A2 (en) 2-(n-heterocyclic amino)thiazolin-4-ones - with respiratory analeptic activity
FR2124164A1 (en) Phenyl pyridazonyl piperazines - analgesics hypotensives sedatives and antibacterials
FR2143526A1 (en) 3-carboxy-4-salicyloxy-6-sulphamoylquinolines - with analgesic,antiinflammatory, antipyretic, antirheumatic activity
FR2153170A1 (en) 4-alkyl-9-alkylaminoalkyl(4h)-thieno(3,2-b)(f)benzazepines - - with antidepressant activity
FR2128349A1 (en) Pseudothiouronium salts and pseudothioureas - plant growth regulators
FR2134812A5 (en) A-oxo-1-(omega-oxo-omega-phenylalkyl)-4,5,6,7-tetrahydro- - indoles - with anticonvulsant, antidepressant, analgesic and sedative
FR2248031A1 (en) 5-oxo dibenzo(a,d)cycloheptene derivs - with analgesic, antipyretic and anti-inflamm- atory activity
FR2219777A1 (en) 5-oxo dibenzo(a,d)cycloheptene derivs - with analgesic, antipyretic and anti-inflamm- atory activity
FR2245348A1 (en) 2-Aryl-2,3,5,6-tetrahydroimidazo(2,1-b)thiazoles - with antidepressant, psychoenergising and anorectic activity