FR2164520A2 - 2-(n-heterocyclic amino)thiazolin-4-ones - with respiratory analeptic activity - Google Patents
2-(n-heterocyclic amino)thiazolin-4-ones - with respiratory analeptic activityInfo
- Publication number
- FR2164520A2 FR2164520A2 FR7146616A FR7146616A FR2164520A2 FR 2164520 A2 FR2164520 A2 FR 2164520A2 FR 7146616 A FR7146616 A FR 7146616A FR 7146616 A FR7146616 A FR 7146616A FR 2164520 A2 FR2164520 A2 FR 2164520A2
- Authority
- FR
- France
- Prior art keywords
- alkyl
- thiazolin
- ones
- heterocyclic amino
- respiratory analeptic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Therapeutic compsns. contg. as active component a cpd. of formula: where R1 is phenyl opt. substd. by >=1 halogen, alkyl, alkoxy; R2 is H, alkyl; A is pyrrolidino, piperidino, piperazino, homopiperazino, morpholino; R3 is alkyl, alkenyl, hydroxyalkyl; phenyl opt. substd. by >=1 halogen, alkyl, alkoxy; benzyl; also their acid-addn. salts. The cpds., originally described in the parent patent as antiinflammatory and analgesic agents, have been found to have respiratory analeptic activity.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR87395A FR6278M (en) | 1966-12-14 | 1966-12-14 | |
FR7146616A FR2164520A2 (en) | 1966-12-14 | 1971-12-24 | 2-(n-heterocyclic amino)thiazolin-4-ones - with respiratory analeptic activity |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR87395A FR6278M (en) | 1966-12-14 | 1966-12-14 | |
FR7146616A FR2164520A2 (en) | 1966-12-14 | 1971-12-24 | 2-(n-heterocyclic amino)thiazolin-4-ones - with respiratory analeptic activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2164520A2 true FR2164520A2 (en) | 1973-08-03 |
FR2164520B2 FR2164520B2 (en) | 1975-02-07 |
Family
ID=26174355
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR87395A Expired FR6278M (en) | 1966-12-14 | 1966-12-14 | |
FR7146616A Granted FR2164520A2 (en) | 1966-12-14 | 1971-12-24 | 2-(n-heterocyclic amino)thiazolin-4-ones - with respiratory analeptic activity |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR87395A Expired FR6278M (en) | 1966-12-14 | 1966-12-14 |
Country Status (1)
Country | Link |
---|---|
FR (2) | FR6278M (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008500353A (en) * | 2004-05-24 | 2008-01-10 | アムゲン インコーポレイティッド | Inhibitors of type 1 11-beta-hydroxysteroid dehydrogenase |
US8686011B2 (en) | 2004-05-24 | 2014-04-01 | Amgen Inc. | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
-
1966
- 1966-12-14 FR FR87395A patent/FR6278M/fr not_active Expired
-
1971
- 1971-12-24 FR FR7146616A patent/FR2164520A2/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008500353A (en) * | 2004-05-24 | 2008-01-10 | アムゲン インコーポレイティッド | Inhibitors of type 1 11-beta-hydroxysteroid dehydrogenase |
US7807700B2 (en) | 2004-05-24 | 2010-10-05 | Amgen Inc. | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
JP4789934B2 (en) * | 2004-05-24 | 2011-10-12 | アムジエン・インコーポレーテツド | Inhibitors of type 1 11-beta-hydroxysteroid dehydrogenase |
US8686011B2 (en) | 2004-05-24 | 2014-04-01 | Amgen Inc. | Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
Also Published As
Publication number | Publication date |
---|---|
FR2164520B2 (en) | 1975-02-07 |
FR6278M (en) | 1968-09-02 |
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