FR2229413A1 - Para-4-quinolyl amino benzene sulphonamides - from a 4-chloro quinoline and a p-amino benzene sulphonamide, hypotensives etc. - Google Patents

Para-4-quinolyl amino benzene sulphonamides - from a 4-chloro quinoline and a p-amino benzene sulphonamide, hypotensives etc.

Info

Publication number
FR2229413A1
FR2229413A1 FR7417126A FR7417126A FR2229413A1 FR 2229413 A1 FR2229413 A1 FR 2229413A1 FR 7417126 A FR7417126 A FR 7417126A FR 7417126 A FR7417126 A FR 7417126A FR 2229413 A1 FR2229413 A1 FR 2229413A1
Authority
FR
France
Prior art keywords
amino benzene
hypotensives
para
sulphonamides
quinolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7417126A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2229413A1 publication Critical patent/FR2229413A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Quinoline Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Quinolylamino benzene sulphonamides of formula (I) and their salts (where X is H, 1-4C alkyl or alkoxy, halogen, or trihalomethyl, R1 is H or 1-4C alkyl, and R2 and R3 are H, 1-4C alkyl, or together with the N atom, form a 4-6 membered satd. heterocycle, morpholino, piperazino or 4-benzyl piperazino, opt. substd. by 1 or 2 lower alkyl gps.) are used as hypotensives, tranquillisers, sedatives and anoretics.
FR7417126A 1973-05-17 1974-05-16 Para-4-quinolyl amino benzene sulphonamides - from a 4-chloro quinoline and a p-amino benzene sulphonamide, hypotensives etc. Withdrawn FR2229413A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36131073A 1973-05-17 1973-05-17

Publications (1)

Publication Number Publication Date
FR2229413A1 true FR2229413A1 (en) 1974-12-13

Family

ID=23421519

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7417126A Withdrawn FR2229413A1 (en) 1973-05-17 1974-05-16 Para-4-quinolyl amino benzene sulphonamides - from a 4-chloro quinoline and a p-amino benzene sulphonamide, hypotensives etc.

Country Status (1)

Country Link
FR (1) FR2229413A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159331A (en) 1978-05-05 1979-06-26 The Upjohn Company Antihypertensive 4-aminoquinolines
US7989462B2 (en) 2003-07-03 2011-08-02 Myrexis, Inc. 4-arylamin-or-4-heteroarylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159331A (en) 1978-05-05 1979-06-26 The Upjohn Company Antihypertensive 4-aminoquinolines
FR2424918A1 (en) * 1978-05-05 1979-11-30 Upjohn Co NEW SUBSTITUTED PIPERAZINES, THEIR PREPARATION AND THEIR USE
US7989462B2 (en) 2003-07-03 2011-08-02 Myrexis, Inc. 4-arylamin-or-4-heteroarylamino-quinazolines and analogs as activators of caspases and inducers of apoptosis and the use thereof
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer

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Legal Events

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