GB1418053A - 2- -o-alkylthio-phenyl-1,3-diazacycloalkene hydrohalides and their production - Google Patents
2- -o-alkylthio-phenyl-1,3-diazacycloalkene hydrohalides and their productionInfo
- Publication number
- GB1418053A GB1418053A GB1892773A GB1892773A GB1418053A GB 1418053 A GB1418053 A GB 1418053A GB 1892773 A GB1892773 A GB 1892773A GB 1892773 A GB1892773 A GB 1892773A GB 1418053 A GB1418053 A GB 1418053A
- Authority
- GB
- United Kingdom
- Prior art keywords
- diazacycloalkene
- hydrohalides
- hydrogen
- alkylthio
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
1418053 2 - (o - Alkylthiophenyl) - 1,3 - diazacycloalkene hydrohalides BADISCRE ANILIN- & SODA-FABRIK AG 19 April 1973 [22 April 1972] 18927/73 Heading C2C The invention comprises 2 - (o - alkylthiophenyl) - 1,3 - diazacycloalkene hydrohalides of the formula in which R<SP>1</SP> is hydrogen, halogen or an aliphatic radical; Y is one of the radicals and the individual radicals R<SP>2</SP> are identical or different and each is hydrogen or an aliphatic radical; R<SP>3</SP> is hydrogen or an aliphatic cycloaliphatic, araliphatic, aromatic or heterocyclic radical; and X is a halogen. The compounds are prepared by reacting a benzothietane-2- spiro-2<SP>1</SP>-(1<SP>1</SP>,3<SP>1</SP>-diazacycloalkane) of the general formula in which R<SP>1</SP> and Y are as above with an alkyl halide of the general formula X-CH 2 -R<SP>3</SP>.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2219841A DE2219841A1 (en) | 1972-04-22 | 1972-04-22 | PROCESS FOR THE PREPARATION OF 2- (OALKYLTHIOPHENYL) -1,3-DIAZACYCLOALKENHYDROHALOGENIDES |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1418053A true GB1418053A (en) | 1975-12-17 |
Family
ID=5842969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1892773A Expired GB1418053A (en) | 1972-04-22 | 1973-04-19 | 2- -o-alkylthio-phenyl-1,3-diazacycloalkene hydrohalides and their production |
Country Status (6)
Country | Link |
---|---|
US (1) | USRE32154E (en) |
JP (1) | JPS4920171A (en) |
CH (1) | CH579054A5 (en) |
DE (1) | DE2219841A1 (en) |
FR (1) | FR2182994B1 (en) |
GB (1) | GB1418053A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001010842A2 (en) * | 1999-08-04 | 2001-02-15 | Millennium Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
WO2002062766A2 (en) * | 2001-02-07 | 2002-08-15 | Millennium Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
US6699873B1 (en) | 1999-08-04 | 2004-03-02 | Millennium Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
WO2005121100A1 (en) * | 2003-06-16 | 2005-12-22 | Gene Logic Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
AU2004202804B2 (en) * | 1999-08-04 | 2009-01-29 | Ore Pharmaceuticals Inc. | Melanocortin-4 Receptor Binding Compounds and Methods of use thereof |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5114482B1 (en) * | 1970-12-29 | 1976-05-10 | ||
US4294843A (en) | 1978-07-13 | 1981-10-13 | Burroughs Wellcome Co. | Anti-protozoal oxadiazole derivatives |
DK294579A (en) * | 1978-07-13 | 1980-01-14 | Wellcome Found | ANTIPROTOZOEL OXADIAZOL DERIVATIVES PROCEDURE FOR THEIR PREPARATION AND THEIR USE |
DOP1981004033A (en) * | 1980-12-23 | 1990-12-29 | Ciba Geigy Ag | PROCEDURE TO PROTECT CROP PLANTS FROM PHYTOTOXIC ACTION OF HERBICIDES. |
DE3379544D1 (en) * | 1982-06-08 | 1989-05-11 | Ciba Geigy Ag | 2-phenyl-2-naphthyl and 2-heterocyclic pyrimidines as antidotes for protecting cultured plants before phytotoxic damages caused by herbicides |
US4648896A (en) * | 1982-11-15 | 1987-03-10 | Ciba-Geigy Corporation | 2-aryl-4,6-dihalopyrimidines as antidote for protecting cultivated plants from phytotoxic damage caused by herbicides |
GB2351081A (en) * | 1999-06-18 | 2000-12-20 | Lilly Forschung Gmbh | Pharmaceutically active imidazoline compounds and analogues thereof |
JPWO2016056606A1 (en) * | 2014-10-07 | 2017-07-20 | 国立大学法人京都大学 | Benzisothiazolopyrimidine derivatives or salts thereof, viral infection inhibitors and pharmaceuticals |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1770208A1 (en) * | 1968-04-13 | 1971-10-07 | Hoechst Ag | Tetrahydropyrimidines and process for their preparation |
US4122263A (en) * | 1973-04-11 | 1978-10-24 | Basf Aktiengesellschaft | Production of 2-(o-alkylthiophenyl)-1,3-diazocycloalkene hydrohalides |
-
1972
- 1972-04-22 DE DE2219841A patent/DE2219841A1/en not_active Withdrawn
-
1973
- 1973-04-18 CH CH560273A patent/CH579054A5/xx not_active IP Right Cessation
- 1973-04-19 GB GB1892773A patent/GB1418053A/en not_active Expired
- 1973-04-20 FR FR7314616A patent/FR2182994B1/fr not_active Expired
- 1973-04-21 JP JP48044698A patent/JPS4920171A/ja active Pending
-
1981
- 1981-02-25 US US06/237,961 patent/USRE32154E/en not_active Expired - Lifetime
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001010842A2 (en) * | 1999-08-04 | 2001-02-15 | Millennium Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
WO2001010842A3 (en) * | 1999-08-04 | 2001-08-16 | Millennium Pharm Inc | Melanocortin-4 receptor binding compounds and methods of use thereof |
US6699873B1 (en) | 1999-08-04 | 2004-03-02 | Millennium Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
US7375125B2 (en) | 1999-08-04 | 2008-05-20 | Ore Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
AU2004202804B2 (en) * | 1999-08-04 | 2009-01-29 | Ore Pharmaceuticals Inc. | Melanocortin-4 Receptor Binding Compounds and Methods of use thereof |
WO2002062766A2 (en) * | 2001-02-07 | 2002-08-15 | Millennium Pharmaceuticals, Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
WO2002062766A3 (en) * | 2001-02-07 | 2002-10-03 | Millennium Pharm Inc | Melanocortin-4 receptor binding compounds and methods of use thereof |
WO2005121100A1 (en) * | 2003-06-16 | 2005-12-22 | Gene Logic Inc. | Melanocortin-4 receptor binding compounds and methods of use thereof |
Also Published As
Publication number | Publication date |
---|---|
USRE32154E (en) | 1986-05-20 |
CH579054A5 (en) | 1976-08-31 |
FR2182994B1 (en) | 1977-07-15 |
DE2219841A1 (en) | 1973-10-25 |
FR2182994A1 (en) | 1973-12-14 |
JPS4920171A (en) | 1974-02-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |