ES413055A1 - 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity - Google Patents

4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Info

Publication number
ES413055A1
ES413055A1 ES413055A ES413055A ES413055A1 ES 413055 A1 ES413055 A1 ES 413055A1 ES 413055 A ES413055 A ES 413055A ES 413055 A ES413055 A ES 413055A ES 413055 A1 ES413055 A1 ES 413055A1
Authority
ES
Spain
Prior art keywords
hydroxybutyramide
derivs
biphenylyl
substd
opt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES413055A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES413055A1 publication Critical patent/ES413055A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Title cpds. are of formula (I): (where R1 is H, halogen, CN, NO2 or amino R2 is H or halogen, and R3 and R4 are H, 1-5C alkyl (opt. substd. by lower alkoxy or OH) or phenyl (opt. substd. by a halogen atom or CF3, OH or lower alkyl or alkoxy gp.), or NR3R4 is pyrrolidino, piperidino, morpholino or piperazino opt. substd. by lower alkyl) and physiologically tolerable salts with acids of those cpds. which are basic.
ES413055A 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity Expired ES413055A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2141926A DE2141926A1 (en) 1971-08-20 1971-08-20 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Publications (1)

Publication Number Publication Date
ES413055A1 true ES413055A1 (en) 1976-01-16

Family

ID=5817372

Family Applications (5)

Application Number Title Priority Date Filing Date
ES405945A Expired ES405945A1 (en) 1971-08-20 1972-08-18 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413055A Expired ES413055A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413056A Expired ES413056A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413053A Expired ES413053A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413054A Expired ES413054A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES405945A Expired ES405945A1 (en) 1971-08-20 1972-08-18 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Family Applications After (3)

Application Number Title Priority Date Filing Date
ES413056A Expired ES413056A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413053A Expired ES413053A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity
ES413054A Expired ES413054A1 (en) 1971-08-20 1973-03-27 4-(4-biphenylyl)-4-hydroxybutyramide derivs - with antiphlogistic activity

Country Status (9)

Country Link
JP (1) JPS4829747A (en)
AT (2) ATA785273A (en)
BG (3) BG20102A3 (en)
DD (1) DD101146A5 (en)
DE (1) DE2141926A1 (en)
ES (5) ES405945A1 (en)
HU (1) HU163805B (en)
PL (1) PL79512B1 (en)
SU (1) SU481151A3 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5178462A (en) * 1974-12-28 1976-07-08 Uragami Riko Kk Suchiimano chusuisochi
FR2817256B1 (en) * 2000-11-27 2005-07-15 Univ Pasteur DERIVATIVES OF 4-HYDROXYBUTANOIC ACID AND ITS SUPERIOR APPROACHES AS GAMMA-HYDROXYBUTYRATE (GHB) RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND PHARMACEUTICAL USES

Also Published As

Publication number Publication date
DD101146A5 (en) 1973-10-20
HU163805B (en) 1973-10-27
ES413054A1 (en) 1976-01-16
ATA785273A (en) 1975-01-15
BG20103A3 (en) 1975-10-30
SU481151A3 (en) 1975-08-15
ES405945A1 (en) 1975-09-16
PL79512B1 (en) 1975-06-30
BG19795A3 (en) 1975-10-10
BG20102A3 (en) 1975-10-30
ES413053A1 (en) 1976-01-16
AT319921B (en) 1975-01-10
ES413056A1 (en) 1976-01-16
DE2141926A1 (en) 1973-03-01
JPS4829747A (en) 1973-04-19

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