ES411163A1 - Procedimiento para preparar penicilinas y cefalosporinas. - Google Patents

Procedimiento para preparar penicilinas y cefalosporinas.

Info

Publication number
ES411163A1
ES411163A1 ES411163A ES411163A ES411163A1 ES 411163 A1 ES411163 A1 ES 411163A1 ES 411163 A ES411163 A ES 411163A ES 411163 A ES411163 A ES 411163A ES 411163 A1 ES411163 A1 ES 411163A1
Authority
ES
Spain
Prior art keywords
formula
phenyl
hydrogen
see formula
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES411163A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of ES411163A1 publication Critical patent/ES411163A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES411163A 1972-01-31 1973-01-31 Procedimiento para preparar penicilinas y cefalosporinas. Expired ES411163A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22229372A 1972-01-31 1972-01-31
US30169472A 1972-10-27 1972-10-27

Publications (1)

Publication Number Publication Date
ES411163A1 true ES411163A1 (es) 1976-04-16

Family

ID=26916655

Family Applications (1)

Application Number Title Priority Date Filing Date
ES411163A Expired ES411163A1 (es) 1972-01-31 1973-01-31 Procedimiento para preparar penicilinas y cefalosporinas.

Country Status (23)

Country Link
US (1) US3994885A (es)
JP (2) JPS4885595A (es)
AR (2) AR209256A1 (es)
AT (1) AT327378B (es)
AU (1) AU465803B2 (es)
BE (1) BE794554A (es)
BG (1) BG34453A3 (es)
CA (1) CA1033718A (es)
CH (1) CH571525A5 (es)
CS (1) CS195262B2 (es)
DD (1) DD103900A5 (es)
DE (1) DE2304226C3 (es)
ES (1) ES411163A1 (es)
FR (1) FR2170051B1 (es)
GB (1) GB1412886A (es)
HU (1) HU170405B (es)
IE (1) IE37252B1 (es)
IL (1) IL41361A (es)
NL (1) NL179207C (es)
PH (1) PH12535A (es)
SE (1) SE418184B (es)
YU (1) YU36964B (es)
ZA (1) ZA73407B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU36181B (en) * 1971-11-29 1982-02-25 Merck & Co Inc Process for obtaining 7-(2-thienylacetamido)-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylates
US4447602A (en) * 1971-11-29 1984-05-08 Merck & Co., Inc. Process to prepare 7-substituted cephalosporins or 6-substituted penicillins
CA1040620A (en) * 1972-11-14 1978-10-17 Frank J. Urban 6-alkoxy-6-acylamidopenicillins 7-alkoxy-7-acylamido acetoxycephalosporins and process
DE2460477A1 (de) * 1973-12-26 1975-07-10 Yamanouchi Pharma Co Ltd Verbessertes verfahren zur herstellung von 6-alkoxy-substituierten penicillinen
US3989696A (en) * 1975-05-01 1976-11-02 E. R. Squibb & Sons, Inc. 3-Heterothio[(oxyalkyl)thioacetyl]cephalosporin derivatives
US3991051A (en) * 1975-05-01 1976-11-09 E. R. Squibb & Sons, Inc. [(Oxyalkyl)thioacetyl]cephalosporin derivatives
JPS5941999B2 (ja) 1975-07-24 1984-10-11 武田薬品工業株式会社 セフエムまたはベナム化合物の製造法
CA1093997A (en) * 1975-12-25 1981-01-20 Shunichi Watanabe Process of producing 7-methoxy cephalosporins
JPS5279081A (en) * 1975-12-25 1977-07-02 Yamanouchi Pharmaceut Co Ltd Preparation of novel 7-methoxycephalosporins
JPS5422391A (en) * 1977-07-21 1979-02-20 Toyama Chem Co Ltd Preparation of novel 7alpha-methoxycephalosporins
US4048160A (en) * 1976-03-22 1977-09-13 Eli Lilly And Company Process for preparation of 7-alkoxy-3-bromomethylcephems
US4048163A (en) * 1976-03-22 1977-09-13 Eli Lilly And Company Process for preparation of 7-alkoxy-3-chloromethylcephems
US4165429A (en) * 1976-06-28 1979-08-21 Yamanouchi Pharmaceutical Co., Ltd. 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES
US4311837A (en) * 1979-05-01 1982-01-19 Eli Lilly And Company Certain heterocyclic thiomethyl derivatives of 7-(dihalogenated phenylthioacetamido)cephalosporanic acids useful in the treatment of infections caused by _Streptococcus faecalis
DE3373475D1 (en) * 1982-12-14 1987-10-15 Beecham Group Plc Process for the preparation of beta-lactam compounds
US5773627A (en) * 1995-03-21 1998-06-30 Betzdearborn Inc. Methods of inhibiting corrosion using halo-benzotriazoles
MY129257A (en) * 1995-03-21 2007-03-30 Betz Laboratories Methods of inhibiting corrosion using halo-benzotriazoles
AR035728A1 (es) * 2001-01-16 2004-07-07 Merck & Co Inc Proceso perfeccionado para la sintesis de carbapenem
AU2003294161A1 (en) * 2003-03-20 2004-10-11 Orchid Chemicals And Pharmaceuticals Ltd An improved process for the preparation of cefoxitin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3775410A (en) * 1971-11-29 1973-11-27 B Christensen Process for preparing cephalosporin compounds
US3780037A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
YU36181B (en) * 1971-11-29 1982-02-25 Merck & Co Inc Process for obtaining 7-(2-thienylacetamido)-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylates
US3780034A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing substituted cephalosporins
US3780031A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds

Also Published As

Publication number Publication date
IL41361A (en) 1979-05-31
ATA78373A (de) 1975-04-15
IE37252B1 (en) 1977-06-08
SE418184B (sv) 1981-05-11
AR209256A1 (es) 1977-04-15
YU22873A (en) 1982-06-18
CA1033718A (en) 1978-06-27
DD103900A5 (es) 1974-02-12
NL179207B (nl) 1986-03-03
DE2304226A1 (de) 1973-08-16
AU5137373A (en) 1974-07-25
GB1412886A (en) 1975-11-05
ZA73407B (en) 1974-09-25
AR209426A1 (es) 1977-04-29
CH571525A5 (es) 1976-01-15
US3994885A (en) 1976-11-30
PH12535A (en) 1979-05-17
JPS4885595A (es) 1973-11-13
BG34453A3 (en) 1983-09-15
FR2170051A1 (es) 1973-09-14
NL7301419A (es) 1973-08-02
YU36964B (en) 1984-08-31
IE37252L (en) 1973-07-31
JPS6021595B2 (ja) 1985-05-28
DE2304226B2 (de) 1979-07-19
IL41361A0 (en) 1973-03-30
CS195262B2 (en) 1980-01-31
HU170405B (es) 1977-06-28
JPS5745188A (en) 1982-03-13
NL179207C (nl) 1986-08-01
DE2304226C3 (de) 1980-04-03
BE794554A (fr) 1973-07-26
FR2170051B1 (es) 1976-10-22
AU465803B2 (en) 1975-10-09
AT327378B (de) 1976-01-26

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