AT327378B - Verfahren zur herstellung von penicillin- und cephalosporinverbindungen - Google Patents

Verfahren zur herstellung von penicillin- und cephalosporinverbindungen

Info

Publication number
AT327378B
AT327378B AT78373*#A AT78373A AT327378B AT 327378 B AT327378 B AT 327378B AT 78373 A AT78373 A AT 78373A AT 327378 B AT327378 B AT 327378B
Authority
AT
Austria
Prior art keywords
penicillin
cephalosporin compounds
cephalosporin
compounds
Prior art date
Application number
AT78373*#A
Other languages
English (en)
Other versions
ATA78373A (de
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US22229372A priority Critical
Priority to US30169472A priority
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ATA78373A publication Critical patent/ATA78373A/de
Application granted granted Critical
Publication of AT327378B publication Critical patent/AT327378B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/577-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44Compounds with an amino radical acylated by carboxylic acids, attached in position 6
AT78373*#A 1972-01-31 1973-01-30 Verfahren zur herstellung von penicillin- und cephalosporinverbindungen AT327378B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US22229372A true 1972-01-31 1972-01-31
US30169472A true 1972-10-27 1972-10-27

Publications (2)

Publication Number Publication Date
ATA78373A ATA78373A (de) 1975-04-15
AT327378B true AT327378B (de) 1976-01-26

Family

ID=26916655

Family Applications (1)

Application Number Title Priority Date Filing Date
AT78373*#A AT327378B (de) 1972-01-31 1973-01-30 Verfahren zur herstellung von penicillin- und cephalosporinverbindungen

Country Status (23)

Country Link
US (1) US3994885A (de)
JP (2) JPS4885595A (de)
AR (2) AR209256A1 (de)
AT (1) AT327378B (de)
AU (1) AU465803B2 (de)
BE (1) BE794554A (de)
BG (1) BG34453A3 (de)
CA (1) CA1033718A (de)
CH (1) CH571525A5 (de)
CS (1) CS195262B2 (de)
DD (1) DD103900A5 (de)
DE (1) DE2304226C3 (de)
ES (1) ES411163A1 (de)
FR (1) FR2170051B1 (de)
GB (1) GB1412886A (de)
HU (1) HU170405B (de)
IE (1) IE37252B1 (de)
IL (1) IL41361A (de)
NL (1) NL179207C (de)
PH (1) PH12535A (de)
SE (1) SE418184B (de)
YU (1) YU36964B (de)
ZA (1) ZA7300407B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU36181B (en) * 1971-11-29 1982-02-25 Merck & Co Inc Process for obtaining 7-(2-thienylacetamido)-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylates
US4447602A (en) * 1971-11-29 1984-05-08 Merck & Co., Inc. Process to prepare 7-substituted cephalosporins or 6-substituted penicillins
CA1040620A (en) * 1972-11-14 1978-10-17 Frank J. Urban 6-alkoxy-6-acylamidopenicillins 7-alkoxy-7-acylamido acetoxycephalosporins and process
DE2460477A1 (de) * 1973-12-26 1975-07-10 Yamanouchi Pharma Co Ltd Verbessertes verfahren zur herstellung von 6-alkoxy-substituierten penicillinen
US3991051A (en) * 1975-05-01 1976-11-09 E. R. Squibb & Sons, Inc. [(Oxyalkyl)thioacetyl]cephalosporin derivatives
US3989696A (en) * 1975-05-01 1976-11-02 E. R. Squibb & Sons, Inc. 3-Heterothio[(oxyalkyl)thioacetyl]cephalosporin derivatives
CA1093997A (en) * 1975-12-25 1981-01-20 Shunichi Watanabe Process of producing 7-methoxy cephalosporins
JPS5635159B2 (de) * 1975-12-25 1981-08-14
US4048163A (en) * 1976-03-22 1977-09-13 Eli Lilly And Company Process for preparation of 7-alkoxy-3-chloromethylcephems
US4048160A (en) * 1976-03-22 1977-09-13 Eli Lilly And Company Process for preparation of 7-alkoxy-3-bromomethylcephems
US4165429A (en) * 1976-06-28 1979-08-21 Yamanouchi Pharmaceutical Co., Ltd. 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES
JPS6341915B2 (de) * 1977-07-21 1988-08-19 Toyama Chemical Co Ltd
US4311837A (en) * 1979-05-01 1982-01-19 Eli Lilly And Company Certain heterocyclic thiomethyl derivatives of 7-(dihalogenated phenylthioacetamido)cephalosporanic acids useful in the treatment of infections caused by _Streptococcus faecalis
EP0112049B1 (de) * 1982-12-14 1987-09-09 Beecham Group Plc Verfahren zur Herstellung von beta-Lactamverbindungen
MY129257A (en) * 1995-03-21 2007-03-30 Betz Laboratories Methods of inhibiting corrosion using halo-benzotriazoles
US5773627A (en) * 1995-03-21 1998-06-30 Betzdearborn Inc. Methods of inhibiting corrosion using halo-benzotriazoles
AR035728A1 (es) * 2001-01-16 2004-07-07 Merck & Co Inc Proceso perfeccionado para la sintesis de carbapenem
US7662955B2 (en) * 2003-03-20 2010-02-16 Orchid Chemicals And Pharmaceuticals Ltd. Process for the preparation of cefoxitin

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3780037A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
YU36181B (en) * 1971-11-29 1982-02-25 Merck & Co Inc Process for obtaining 7-(2-thienylacetamido)-7-methoxy-3-carbamoyloxymethyl-3-cephem-4-carboxylates
US3775410A (en) * 1971-11-29 1973-11-27 B Christensen Process for preparing cephalosporin compounds
US3780031A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing cephalosporin compounds
US3780034A (en) * 1971-11-29 1973-12-18 Merck & Co Inc Process for preparing substituted cephalosporins

Also Published As

Publication number Publication date
DE2304226C3 (de) 1980-04-03
AR209256A1 (es) 1977-04-15
AU465803B2 (en) 1975-10-09
FR2170051A1 (de) 1973-09-14
CH571525A5 (de) 1976-01-15
BE794554A (fr) 1973-07-26
CS195262B2 (en) 1980-01-31
DE2304226A1 (de) 1973-08-16
US3994885A (en) 1976-11-30
AR209426A1 (es) 1977-04-29
YU22873A (en) 1982-06-18
IE37252B1 (en) 1977-06-08
GB1412886A (en) 1975-11-05
NL179207B (nl) 1986-03-03
IL41361A (en) 1979-05-31
ATA78373A (de) 1975-04-15
JPS6021595B2 (de) 1985-05-28
NL7301419A (de) 1973-08-02
PH12535A (en) 1979-05-17
CA1033718A1 (de)
JPS5745188A (en) 1982-03-13
HU170405B (de) 1977-06-28
IL41361D0 (en) 1973-03-30
IE37252L (en) 1973-07-31
BG34453A3 (bg) 1983-09-15
YU36964B (en) 1984-08-31
AU5137373A (en) 1974-07-25
FR2170051B1 (de) 1976-10-22
NL179207C (nl) 1986-08-01
BE794554A1 (de)
SE418184B (sv) 1981-05-11
CA1033718A (en) 1978-06-27
DD103900A5 (de) 1974-02-12
JPS4885595A (de) 1973-11-13
ES411163A1 (es) 1976-04-16
DE2304226B2 (de) 1979-07-19
ZA7300407B (en) 1974-09-25

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee