ES410490A1 - Manufacture of isoindoline derivative - Google Patents

Manufacture of isoindoline derivative

Info

Publication number
ES410490A1
ES410490A1 ES410490A ES410490A ES410490A1 ES 410490 A1 ES410490 A1 ES 410490A1 ES 410490 A ES410490 A ES 410490A ES 410490 A ES410490 A ES 410490A ES 410490 A1 ES410490 A1 ES 410490A1
Authority
ES
Spain
Prior art keywords
manufacture
formula
isoindoline derivative
methylpiperazine
cpd
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES410490A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc SA
Original Assignee
Rhone Poulenc SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc SA filed Critical Rhone Poulenc SA
Publication of ES410490A1 publication Critical patent/ES410490A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03G—ELECTROGRAPHY; ELECTROPHOTOGRAPHY; MAGNETOGRAPHY
    • G03G15/00—Apparatus for electrographic processes using a charge pattern
    • G03G15/14—Apparatus for electrographic processes using a charge pattern for transferring a pattern to a second base
    • G03G15/16—Apparatus for electrographic processes using a charge pattern for transferring a pattern to a second base of a toner pattern, e.g. a powder pattern, e.g. magnetic transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Title derivs are cpds of formula (I) (where X is halogen, 1-4C alkyl, 1-4C alkoxy, NO2 and/or H Y is halogen, 1-4C alkyl, 1-4C alkoxy, CN, NO2 and/or H and n is 0 or 1) and their acid addition salts. (I) in which n is 0 are obtained by reacting an alkali salt of a cpd of formula (II) with 1-chlorocarbonyl-4-methylpiperazine or by reacting a cpd of formula (II. -OH=-OCOOAr) (where Ar is opt. substituted aryl) with 1-methylpiperazine, and may be converted into (I) in which n is 1 by oxidn.
ES410490A 1972-01-10 1973-01-10 Manufacture of isoindoline derivative Expired ES410490A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7200650A FR2167217A1 (en) 1972-01-10 1972-01-10 Isoindolino-quinoline derivs - useful as tranquillizers and anticonvulsants

Publications (1)

Publication Number Publication Date
ES410490A1 true ES410490A1 (en) 1975-12-01

Family

ID=9091655

Family Applications (2)

Application Number Title Priority Date Filing Date
ES410489A Expired ES410489A1 (en) 1972-01-10 1973-01-10 Manufacture of isoindoline derivative
ES410490A Expired ES410490A1 (en) 1972-01-10 1973-01-10 Manufacture of isoindoline derivative

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES410489A Expired ES410489A1 (en) 1972-01-10 1973-01-10 Manufacture of isoindoline derivative

Country Status (10)

Country Link
JP (1) JPS5622780A (en)
AR (1) AR202800A1 (en)
AU (1) AU468083B2 (en)
CS (2) CS181748B2 (en)
ES (2) ES410489A1 (en)
FR (1) FR2167217A1 (en)
PL (2) PL92423B1 (en)
SU (2) SU488409A3 (en)
YU (2) YU187473A (en)
ZA (1) ZA73118B (en)

Also Published As

Publication number Publication date
CS181748B2 (en) 1978-03-31
AU468083B2 (en) 1975-12-18
JPS5653310B2 (en) 1981-12-17
YU184773A (en) 1980-10-31
AU5087673A (en) 1974-07-11
FR2167217B1 (en) 1975-06-13
PL89131B1 (en) 1976-10-30
YU187473A (en) 1980-10-31
SU488409A3 (en) 1975-10-15
CS181717B2 (en) 1978-03-31
ES410489A1 (en) 1975-12-01
YU35766B (en) 1981-06-30
AR202800A1 (en) 1975-07-24
ZA73118B (en) 1973-09-26
FR2167217A1 (en) 1973-08-24
PL92423B1 (en) 1977-04-30
SU499805A3 (en) 1976-01-15
JPS5622780A (en) 1981-03-03

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19870228