ES404085A1 - A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES404085A1
ES404085A1 ES404085A ES404085A ES404085A1 ES 404085 A1 ES404085 A1 ES 404085A1 ES 404085 A ES404085 A ES 404085A ES 404085 A ES404085 A ES 404085A ES 404085 A1 ES404085 A1 ES 404085A1
Authority
ES
Spain
Prior art keywords
translation
preparation
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES404085A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES404085A1 publication Critical patent/ES404085A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catalysts (AREA)

Abstract

A process for the preparation of benzodiazepine derivatives and especially 7-chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine, 7-chloro-2,3-dihydro-5- phenyl-1H-1,4-benzodiazepine and the acid addition salts thereof, characterized by catalytically hydrogenating a compound of the general formula ** (see formula) ** In which R represents a hydrogen atom or a methyl group, In the presence of raney nickel or raney cobalt and, if desired, converting the obtained compound to an acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES404085A 1971-06-22 1972-06-21 A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES404085A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH910671A CH551986A (en) 1971-06-22 1971-06-22 7-chloro-2,3-dihydro-(1-methyl)-5-phenyl-1h-1,4-benzodiazepine - prepn - by catalytic hydrogenation of (2-benzoyl 4-chloro-n-methylani

Publications (1)

Publication Number Publication Date
ES404085A1 true ES404085A1 (en) 1975-11-16

Family

ID=4348387

Family Applications (1)

Application Number Title Priority Date Filing Date
ES404085A Expired ES404085A1 (en) 1971-06-22 1972-06-21 A procedure for the preparation of benzodiacepine derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (13)

Country Link
JP (1) JPS5440557B1 (en)
AR (1) AR192947A1 (en)
AT (1) AT318622B (en)
CA (1) CA966834A (en)
CH (1) CH551986A (en)
DK (1) DK145223C (en)
ES (1) ES404085A1 (en)
FI (1) FI54114C (en)
HU (1) HU163717B (en)
NL (1) NL177594C (en)
NO (1) NO140668C (en)
SE (1) SE397977B (en)
YU (1) YU34526B (en)

Also Published As

Publication number Publication date
AT318622B (en) 1974-11-11
FI54114B (en) 1978-06-30
HU163717B (en) 1973-10-27
DK145223B (en) 1982-10-11
JPS5440557B1 (en) 1979-12-04
CA966834A (en) 1975-04-29
YU135272A (en) 1979-02-28
AR192947A1 (en) 1973-03-21
YU34526B (en) 1979-09-10
SE397977B (en) 1977-11-28
NL177594C (en) 1985-10-16
NL7205955A (en) 1972-12-28
CH551986A (en) 1974-07-31
NO140668B (en) 1979-07-09
DK145223C (en) 1983-02-28
NO140668C (en) 1979-10-17
FI54114C (en) 1978-10-10
NL177594B (en) 1985-05-17

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19890216