ES398016A1 - Procedimiento para el aislamiento de factor estabilizador- de fibrina. - Google Patents
Procedimiento para el aislamiento de factor estabilizador- de fibrina.Info
- Publication number
- ES398016A1 ES398016A1 ES398016A ES398016A ES398016A1 ES 398016 A1 ES398016 A1 ES 398016A1 ES 398016 A ES398016 A ES 398016A ES 398016 A ES398016 A ES 398016A ES 398016 A1 ES398016 A1 ES 398016A1
- Authority
- ES
- Spain
- Prior art keywords
- solution
- nacl
- alkali metal
- neutral
- mixed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108010071289 Factor XIII Proteins 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 6
- 230000007935 neutral effect Effects 0.000 abstract 4
- 239000011780 sodium chloride Substances 0.000 abstract 4
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 abstract 2
- 229910001514 alkali metal chloride Inorganic materials 0.000 abstract 2
- 239000008103 glucose Substances 0.000 abstract 2
- 239000002244 precipitate Substances 0.000 abstract 2
- VRQURTHVUQBIMS-UHFFFAOYSA-N 2-acridin-1-yloxyethane-1,1-diamine;2-hydroxypropanoic acid Chemical compound CC(O)C(O)=O.C1=CC=C2C=C3C(OCC(N)N)=CC=CC3=NC2=C1 VRQURTHVUQBIMS-UHFFFAOYSA-N 0.000 abstract 1
- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 abstract 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 229960002684 aminocaproic acid Drugs 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 abstract 1
- 239000001913 cellulose Substances 0.000 abstract 1
- 229920002678 cellulose Polymers 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 239000012535 impurity Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 210000002826 placenta Anatomy 0.000 abstract 1
- 239000001488 sodium phosphate Substances 0.000 abstract 1
- 229910000162 sodium phosphate Inorganic materials 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000003381 stabilizer Substances 0.000 abstract 1
- 239000006228 supernatant Substances 0.000 abstract 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/104—Aminoacyltransferases (2.3.2)
- C12N9/1044—Protein-glutamine gamma-glutamyltransferase (2.3.2.13), i.e. transglutaminase or factor XIII
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2063070A DE2063070C3 (de) | 1970-12-22 | 1970-12-22 | Verfahren zur Herstellung eines Arzneimittels mit fibrinstabilisierender Wirkung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES398016A1 true ES398016A1 (es) | 1974-07-16 |
Family
ID=5791794
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES398016A Expired ES398016A1 (es) | 1970-12-22 | 1971-12-16 | Procedimiento para el aislamiento de factor estabilizador- de fibrina. |
Country Status (15)
| Country | Link |
|---|---|
| JP (1) | JPS5421402B1 (pm) |
| AT (1) | AT310941B (pm) |
| AU (1) | AU432182B2 (pm) |
| BE (1) | BE777136A (pm) |
| BR (1) | BR7108490D0 (pm) |
| CA (1) | CA957943A (pm) |
| CH (1) | CH575235A5 (pm) |
| DE (1) | DE2063070C3 (pm) |
| DK (1) | DK127227B (pm) |
| ES (1) | ES398016A1 (pm) |
| FR (1) | FR2119009B1 (pm) |
| GB (1) | GB1380056A (pm) |
| IL (1) | IL38403A (pm) |
| NL (1) | NL159582B (pm) |
| SE (1) | SE371930B (pm) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE454745B (sv) * | 1982-12-10 | 1988-05-30 | Cubana Importadora Y Exportado | Produkt for att stimulera syntesen av melanotiskt pigment i huden vid botande av vigiligo |
| FR2600078B1 (fr) * | 1986-06-12 | 1989-07-13 | Merieux Inst | Procede de preparation de facteur xiii a partir du placenta |
| DE3734923C1 (de) * | 1987-10-15 | 1989-01-26 | Biotest Pharma Gmbh | Verfahren zur Herstellung einer sterilen Plasmaproteinloesung,die Fibrinogen und den Gerinnungsfaktor XIII enthaelt |
| JPH01216939A (ja) * | 1988-02-24 | 1989-08-30 | Hoechst Japan Kk | 末熟児頭蓋内出血阻止剤 |
| DE3808048A1 (de) * | 1988-03-11 | 1989-09-21 | Behringwerke Ag | Verfahren zum affinitaetschromatografischen reinigen von faktor xiii |
| WO1991000098A1 (en) * | 1989-06-23 | 1991-01-10 | Kishinevsky Selskokhozyaistvenny Institut Imeni M.V.Frunze | Anti-inflammatory preparation and method of obtaining it |
| DE19508192A1 (de) | 1995-03-09 | 1996-09-12 | Behringwerke Ag | Stabile Transglutaminasepräparate und Verfahren zu ihrer Herstellung |
-
1970
- 1970-12-22 DE DE2063070A patent/DE2063070C3/de not_active Expired
-
1971
- 1971-12-16 ES ES398016A patent/ES398016A1/es not_active Expired
- 1971-12-17 NL NL7117363.A patent/NL159582B/xx not_active IP Right Cessation
- 1971-12-17 CH CH1850871A patent/CH575235A5/xx not_active IP Right Cessation
- 1971-12-20 SE SE7116299A patent/SE371930B/xx unknown
- 1971-12-20 AU AU37088/71A patent/AU432182B2/en not_active Expired
- 1971-12-20 IL IL38403A patent/IL38403A/xx unknown
- 1971-12-20 CA CA130,488A patent/CA957943A/en not_active Expired
- 1971-12-21 AT AT1096271A patent/AT310941B/de not_active IP Right Cessation
- 1971-12-21 DK DK626471AA patent/DK127227B/da unknown
- 1971-12-22 BR BR8490/71A patent/BR7108490D0/pt unknown
- 1971-12-22 GB GB5972271A patent/GB1380056A/en not_active Expired
- 1971-12-22 BE BE777136A patent/BE777136A/xx unknown
- 1971-12-22 FR FR7146139A patent/FR2119009B1/fr not_active Expired
- 1971-12-22 JP JP10451871A patent/JPS5421402B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR7108490D0 (pt) | 1973-05-08 |
| SE371930B (pm) | 1974-12-09 |
| IL38403A (en) | 1975-04-25 |
| DE2063070B2 (de) | 1974-12-05 |
| CH575235A5 (pm) | 1976-05-14 |
| FR2119009B1 (pm) | 1975-03-14 |
| DE2063070C3 (de) | 1975-07-24 |
| NL159582B (nl) | 1979-03-15 |
| GB1380056A (en) | 1975-01-08 |
| DK127227B (da) | 1973-10-08 |
| FR2119009A1 (pm) | 1972-08-04 |
| AU3708871A (en) | 1973-02-15 |
| JPS5421402B1 (pm) | 1979-07-30 |
| AU432182B2 (en) | 1973-02-15 |
| BE777136A (fr) | 1972-06-22 |
| DE2063070A1 (de) | 1972-06-29 |
| NL7117363A (pm) | 1972-06-26 |
| IL38403A0 (en) | 1972-02-29 |
| AT310941B (de) | 1973-10-25 |
| CA957943A (en) | 1974-11-19 |
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