ES392575A1 - Un proceso de aislamiento de alfa-6 deoxitetraciclinas de gran pureza. - Google Patents
Un proceso de aislamiento de alfa-6 deoxitetraciclinas de gran pureza.Info
- Publication number
- ES392575A1 ES392575A1 ES392575A ES392575A ES392575A1 ES 392575 A1 ES392575 A1 ES 392575A1 ES 392575 A ES392575 A ES 392575A ES 392575 A ES392575 A ES 392575A ES 392575 A1 ES392575 A1 ES 392575A1
- Authority
- ES
- Spain
- Prior art keywords
- deoxytetracyclines
- reaction mixture
- products
- impurities
- doxycycline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960003722 doxycycline Drugs 0.000 title 1
- XQTWDDCIUJNLTR-CVHRZJFOSA-N doxycycline monohydrate Chemical compound O.O=C1C2=C(O)C=CC=C2[C@H](C)[C@@H]2C1=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@@H](N(C)C)[C@@H]1[C@H]2O XQTWDDCIUJNLTR-CVHRZJFOSA-N 0.000 title 1
- 238000011084 recovery Methods 0.000 title 1
- 239000011541 reaction mixture Substances 0.000 abstract 3
- 239000012535 impurity Substances 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000006227 byproduct Substances 0.000 abstract 1
- 159000000007 calcium salts Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007857 degradation product Substances 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT5410970 | 1970-07-03 | ||
| PT5410971 | 1971-06-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES392575A1 true ES392575A1 (es) | 1973-01-01 |
Family
ID=26653423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES392575A Expired ES392575A1 (es) | 1970-07-03 | 1972-06-23 | Un proceso de aislamiento de alfa-6 deoxitetraciclinas de gran pureza. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5632303B1 (enEXAMPLES) |
| AT (1) | AT318803B (enEXAMPLES) |
| CA (1) | CA945546A (enEXAMPLES) |
| CH (1) | CH588445A5 (enEXAMPLES) |
| DE (1) | DE2131945B2 (enEXAMPLES) |
| ES (1) | ES392575A1 (enEXAMPLES) |
| FR (1) | FR2148660A5 (enEXAMPLES) |
| GB (1) | GB1360998A (enEXAMPLES) |
| HK (1) | HK78879A (enEXAMPLES) |
| NL (1) | NL7109000A (enEXAMPLES) |
| ZA (1) | ZA714323B (enEXAMPLES) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3795707A (en) * | 1970-12-28 | 1974-03-05 | Rachelle Labor Italia Spa | Manufacture of alpha-6-deoxytetracyclines |
| CN103040773A (zh) * | 2003-07-25 | 2013-04-17 | 沃纳奇尔科特有限责任公司 | 多西环素金属络合物固体剂型 |
| CN107162924A (zh) * | 2017-05-16 | 2017-09-15 | 扬州联博药业有限公司 | 一种从盐酸多西环素精制母液中回收多西环素的方法 |
-
1971
- 1971-06-25 CA CA116,691A patent/CA945546A/en not_active Expired
- 1971-06-26 DE DE19712131945 patent/DE2131945B2/de not_active Withdrawn
- 1971-06-28 GB GB3012171A patent/GB1360998A/en not_active Expired
- 1971-06-29 NL NL7109000A patent/NL7109000A/xx not_active Application Discontinuation
- 1971-06-30 CH CH961271A patent/CH588445A5/xx not_active IP Right Cessation
- 1971-07-01 ZA ZA714323A patent/ZA714323B/xx unknown
- 1971-07-02 JP JP7148699A patent/JPS5632303B1/ja active Pending
- 1971-07-02 FR FR7124329A patent/FR2148660A5/fr not_active Expired
- 1971-07-05 AT AT580271A patent/AT318803B/de not_active IP Right Cessation
-
1972
- 1972-06-23 ES ES392575A patent/ES392575A1/es not_active Expired
-
1979
- 1979-11-15 HK HK788/79A patent/HK78879A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7109000A (enEXAMPLES) | 1972-01-05 |
| DE2131945B2 (de) | 1973-06-07 |
| HK78879A (en) | 1979-11-23 |
| CA945546A (en) | 1974-04-16 |
| FR2148660A5 (enEXAMPLES) | 1973-03-23 |
| ZA714323B (en) | 1972-03-29 |
| JPS5632303B1 (enEXAMPLES) | 1981-07-27 |
| GB1360998A (en) | 1974-07-24 |
| CH588445A5 (enEXAMPLES) | 1977-06-15 |
| DE2131945A1 (de) | 1972-01-20 |
| AT318803B (de) | 1974-10-25 |
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