ES376067A1 - Un procedimiento para la preparacion de acidos 5-ciclohexil - 1 - indacarboxilicos. - Google Patents

Un procedimiento para la preparacion de acidos 5-ciclohexil - 1 - indacarboxilicos.

Info

Publication number
ES376067A1
ES376067A1 ES376067A ES376067A ES376067A1 ES 376067 A1 ES376067 A1 ES 376067A1 ES 376067 A ES376067 A ES 376067A ES 376067 A ES376067 A ES 376067A ES 376067 A1 ES376067 A1 ES 376067A1
Authority
ES
Spain
Prior art keywords
formula
lower alkyl
compound
see formula
produce
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES376067A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES376067A1 publication Critical patent/ES376067A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/55—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ES376067A 1969-01-31 1970-01-30 Un procedimiento para la preparacion de acidos 5-ciclohexil - 1 - indacarboxilicos. Expired ES376067A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79572669A 1969-01-31 1969-01-31

Publications (1)

Publication Number Publication Date
ES376067A1 true ES376067A1 (es) 1972-05-16

Family

ID=25166286

Family Applications (1)

Application Number Title Priority Date Filing Date
ES376067A Expired ES376067A1 (es) 1969-01-31 1970-01-30 Un procedimiento para la preparacion de acidos 5-ciclohexil - 1 - indacarboxilicos.

Country Status (11)

Country Link
JP (2) JPS4925662B1 (no)
BE (1) BE745177A (no)
CH (2) CH544055A (no)
DE (1) DE2004038C3 (no)
DK (1) DK130582B (no)
ES (1) ES376067A1 (no)
FR (1) FR2034514B1 (no)
GB (1) GB1291644A (no)
NL (1) NL165930C (no)
SE (1) SE345995B (no)
YU (1) YU34270B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5530487U (no) * 1978-08-18 1980-02-27
JPS57156434A (en) * 1981-03-19 1982-09-27 Takeda Chem Ind Ltd Zinc indanecarboxylate
JPS63143813U (no) * 1987-03-13 1988-09-21
NZ542962A (en) * 2003-04-15 2008-08-29 Inflazyme Pharm Ltd Indene derivatives as pharmaceutical agents
JP6407951B2 (ja) 2013-03-14 2018-10-17 アクイノックス ファーマシューティカルズ （カナダ） インコーポレイテッド Ｓｈｉｐ１モジュレーターおよびそれに関連する組成物および方法
AU2014228574B2 (en) 2013-03-14 2018-07-26 Aquinox Pharmaceuticals (Canada) Inc. SHIP1 modulators and methods related thereto
WO2016210146A1 (en) 2015-06-26 2016-12-29 Aquinox Pharmaceuticals (Canada) Inc. Crystalline solid forms of the acetate salt of (1s,3s,4r)-4-((3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1h-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol
AU2017209430A1 (en) 2016-01-20 2018-07-12 Aquinox Pharmaceuticals (Canada) Inc. Synthesis of a substituted indene derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2886589A (en) * 1957-08-05 1959-05-12 Merck & Co Inc 8-methyl-5-oxyphenyl hexahydroindan compounds
JPS5121981B1 (no) * 1967-09-11 1976-07-06

Also Published As

Publication number Publication date
DE2004038A1 (de) 1970-08-06
DE2004038B2 (de) 1981-07-23
YU34270B (en) 1979-04-30
JPS5136271B1 (no) 1976-10-07
SE345995B (no) 1972-06-19
NL7001380A (no) 1970-08-04
DK130582C (no) 1975-08-18
CH565132A5 (no) 1975-08-15
CH544055A (de) 1973-11-15
NL165930B (nl) 1981-01-15
YU21170A (en) 1978-10-31
FR2034514A1 (no) 1970-12-11
GB1291644A (en) 1972-10-04
DE2004038C3 (de) 1982-03-25
FR2034514B1 (no) 1973-07-13
JPS4925662B1 (no) 1974-07-02
NL165930C (nl) 1981-06-15
DK130582B (da) 1975-03-10
BE745177A (fr) 1970-07-29

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