CH544055A - Verfahren zur Herstellung von racemischen Gemischen oder optisch aktiven Isomeren von 5-Cyclohexyl-1-indancarbonsäuren - Google Patents

Verfahren zur Herstellung von racemischen Gemischen oder optisch aktiven Isomeren von 5-Cyclohexyl-1-indancarbonsäuren

Info

Publication number
CH544055A
CH544055A CH135070A CH135070A CH544055A CH 544055 A CH544055 A CH 544055A CH 135070 A CH135070 A CH 135070A CH 135070 A CH135070 A CH 135070A CH 544055 A CH544055 A CH 544055A
Authority
CH
Switzerland
Prior art keywords
cyclohexyl
preparation
optically active
racemic mixtures
active isomers
Prior art date
Application number
CH135070A
Other languages
English (en)
Inventor
Frederick Juby Peter
Anthony Partyka Richard
William Hudyma Thomas
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH544055A publication Critical patent/CH544055A/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/55Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/46Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CH135070A 1969-01-31 1970-01-30 Verfahren zur Herstellung von racemischen Gemischen oder optisch aktiven Isomeren von 5-Cyclohexyl-1-indancarbonsäuren CH544055A (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79572669A 1969-01-31 1969-01-31

Publications (1)

Publication Number Publication Date
CH544055A true CH544055A (de) 1973-11-15

Family

ID=25166286

Family Applications (2)

Application Number Title Priority Date Filing Date
CH135070A CH544055A (de) 1969-01-31 1970-01-30 Verfahren zur Herstellung von racemischen Gemischen oder optisch aktiven Isomeren von 5-Cyclohexyl-1-indancarbonsäuren
CH934073A CH565132A5 (de) 1969-01-31 1970-01-30

Family Applications After (1)

Application Number Title Priority Date Filing Date
CH934073A CH565132A5 (de) 1969-01-31 1970-01-30

Country Status (11)

Country Link
JP (2) JPS4925662B1 (de)
BE (1) BE745177A (de)
CH (2) CH544055A (de)
DE (1) DE2004038C3 (de)
DK (1) DK130582B (de)
ES (1) ES376067A1 (de)
FR (1) FR2034514B1 (de)
GB (1) GB1291644A (de)
NL (1) NL165930C (de)
SE (1) SE345995B (de)
YU (1) YU34270B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5530487U (de) * 1978-08-18 1980-02-27
JPS57156434A (en) * 1981-03-19 1982-09-27 Takeda Chem Ind Ltd Zinc indanecarboxylate
JPS63143813U (de) * 1987-03-13 1988-09-21
EP1615866B1 (de) * 2003-04-15 2011-02-16 Aquinox Pharmaceuticals Inc. Inden derivate als pharmazeutika
BR112015022577A2 (pt) 2013-03-14 2017-07-18 Aquinox Pharmaceuticals Canada Inc moduladores ship1 e métodos relacionados a esse
BR112015023009A2 (pt) 2013-03-14 2017-08-22 Aquinox Pharmaceuticals Inc Moduladores de ship1 e métodos relacionados ao mesmo
CN107787315A (zh) 2015-06-26 2018-03-09 阿奎诺克斯药物(加拿大)公司 (1s,3s,4r)‑4‑((3as,4r,5s,7as)‑4‑(氨甲基)‑7a‑甲基‑1‑亚甲基八氢‑1h‑茚‑5‑基)‑3‑(羟甲基)‑4‑甲基环己醇的乙酸盐的结晶固体形式
US10053415B2 (en) 2016-01-20 2018-08-21 Aquinox Pharmaceuticals (Canada) Inc. Synthesis of a substituted indene derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2886589A (en) * 1957-08-05 1959-05-12 Merck & Co Inc 8-methyl-5-oxyphenyl hexahydroindan compounds
JPS5121981B1 (de) * 1967-09-11 1976-07-06

Also Published As

Publication number Publication date
NL165930B (nl) 1981-01-15
DK130582C (de) 1975-08-18
YU21170A (en) 1978-10-31
DE2004038B2 (de) 1981-07-23
YU34270B (en) 1979-04-30
DK130582B (da) 1975-03-10
JPS5136271B1 (de) 1976-10-07
SE345995B (de) 1972-06-19
FR2034514A1 (de) 1970-12-11
DE2004038A1 (de) 1970-08-06
GB1291644A (en) 1972-10-04
BE745177A (fr) 1970-07-29
FR2034514B1 (de) 1973-07-13
DE2004038C3 (de) 1982-03-25
CH565132A5 (de) 1975-08-15
NL165930C (nl) 1981-06-15
ES376067A1 (es) 1972-05-16
NL7001380A (de) 1970-08-04
JPS4925662B1 (de) 1974-07-02

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Legal Events

Date Code Title Description
PL Patent ceased