CH544055A - Process for the preparation of racemic mixtures or optically active isomers of 5-cyclohexyl-1-indanecarboxylic acids - Google Patents

Process for the preparation of racemic mixtures or optically active isomers of 5-cyclohexyl-1-indanecarboxylic acids

Info

Publication number
CH544055A
CH544055A CH135070A CH135070A CH544055A CH 544055 A CH544055 A CH 544055A CH 135070 A CH135070 A CH 135070A CH 135070 A CH135070 A CH 135070A CH 544055 A CH544055 A CH 544055A
Authority
CH
Switzerland
Prior art keywords
cyclohexyl
preparation
optically active
racemic mixtures
active isomers
Prior art date
Application number
CH135070A
Other languages
German (de)
Inventor
Frederick Juby Peter
Anthony Partyka Richard
William Hudyma Thomas
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of CH544055A publication Critical patent/CH544055A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/55—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
CH135070A 1969-01-31 1970-01-30 Process for the preparation of racemic mixtures or optically active isomers of 5-cyclohexyl-1-indanecarboxylic acids CH544055A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79572669A 1969-01-31 1969-01-31

Publications (1)

Publication Number Publication Date
CH544055A true CH544055A (en) 1973-11-15

Family

ID=25166286

Family Applications (2)

Application Number Title Priority Date Filing Date
CH934073A CH565132A5 (en) 1969-01-31 1970-01-30
CH135070A CH544055A (en) 1969-01-31 1970-01-30 Process for the preparation of racemic mixtures or optically active isomers of 5-cyclohexyl-1-indanecarboxylic acids

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH934073A CH565132A5 (en) 1969-01-31 1970-01-30

Country Status (11)

Country Link
JP (2) JPS4925662B1 (en)
BE (1) BE745177A (en)
CH (2) CH565132A5 (en)
DE (1) DE2004038C3 (en)
DK (1) DK130582B (en)
ES (1) ES376067A1 (en)
FR (1) FR2034514B1 (en)
GB (1) GB1291644A (en)
NL (1) NL165930C (en)
SE (1) SE345995B (en)
YU (1) YU34270B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5530487U (en) * 1978-08-18 1980-02-27
JPS57156434A (en) * 1981-03-19 1982-09-27 Takeda Chem Ind Ltd Zinc indanecarboxylate
JPS63143813U (en) * 1987-03-13 1988-09-21
ATE498600T1 (en) * 2003-04-15 2011-03-15 Aquinox Pharmaceuticals Inc INDENE DERIVATIVES AS PHARMACEUTICALS
CN105164108B (en) 2013-03-14 2018-07-17 阿奎诺克斯药物（加拿大）公司 SHIP1 conditioning agents and relative method
CA2902764A1 (en) 2013-03-14 2014-09-18 Aquinox Pharmaceuticals (Canada) Inc. Ship1 modulators and methods related thereto
CN107787315A (en) 2015-06-26 2018-03-09 阿奎诺克斯药物（加拿大）公司 (1S, 3S, 4R) 4 ((3AS, 4R, 5S, 7AS) 4 (aminomethyl) 7A methyl, 1 methylene octahydro 1H indenes, 5 base) 3 (methylol) 4 methyl cyclohexanol acetate crystalline solid forms
WO2017127753A1 (en) 2016-01-20 2017-07-27 Aquinox Pharmaceuticals (Canada) Inc. Synthesis of a substituted indene derivative

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2886589A (en) * 1957-08-05 1959-05-12 Merck & Co Inc 8-methyl-5-oxyphenyl hexahydroindan compounds
JPS5121981B1 (en) * 1967-09-11 1976-07-06

Also Published As

Publication number Publication date
ES376067A1 (en) 1972-05-16
JPS4925662B1 (en) 1974-07-02
YU34270B (en) 1979-04-30
YU21170A (en) 1978-10-31
BE745177A (en) 1970-07-29
NL165930B (en) 1981-01-15
SE345995B (en) 1972-06-19
JPS5136271B1 (en) 1976-10-07
DK130582C (en) 1975-08-18
DE2004038A1 (en) 1970-08-06
NL7001380A (en) 1970-08-04
FR2034514A1 (en) 1970-12-11
GB1291644A (en) 1972-10-04
FR2034514B1 (en) 1973-07-13
DK130582B (en) 1975-03-10
DE2004038B2 (en) 1981-07-23
CH565132A5 (en) 1975-08-15
DE2004038C3 (en) 1982-03-25
NL165930C (en) 1981-06-15

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Legal Events

Date Code Title Description
PL Patent ceased