GB1291644A - Substituted 1-indancarboxylic acids, their esters and salts - Google Patents

Substituted 1-indancarboxylic acids, their esters and salts

Info

Publication number
GB1291644A
GB1291644A GB4535/70A GB453570A GB1291644A GB 1291644 A GB1291644 A GB 1291644A GB 4535/70 A GB4535/70 A GB 4535/70A GB 453570 A GB453570 A GB 453570A GB 1291644 A GB1291644 A GB 1291644A
Authority
GB
United Kingdom
Prior art keywords
compounds
salts
acid
esters
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4535/70A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB1291644A publication Critical patent/GB1291644A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/55—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
    • C07C45/513—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups the singly bound functional group being an etherified hydroxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
GB4535/70A 1969-01-31 1970-01-30 Substituted 1-indancarboxylic acids, their esters and salts Expired GB1291644A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79572669A 1969-01-31 1969-01-31

Publications (1)

Publication Number Publication Date
GB1291644A true GB1291644A (en) 1972-10-04

Family

ID=25166286

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4535/70A Expired GB1291644A (en) 1969-01-31 1970-01-30 Substituted 1-indancarboxylic acids, their esters and salts

Country Status (11)

Country Link
JP (2) JPS4925662B1 (no)
BE (1) BE745177A (no)
CH (2) CH544055A (no)
DE (1) DE2004038C3 (no)
DK (1) DK130582B (no)
ES (1) ES376067A1 (no)
FR (1) FR2034514B1 (no)
GB (1) GB1291644A (no)
NL (1) NL165930C (no)
SE (1) SE345995B (no)
YU (1) YU34270B (no)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0061308A1 (en) * 1981-03-19 1982-09-29 Takeda Chemical Industries, Ltd. Indancarboxylic acid zinc salts and production thereof
CN102010298A (zh) * 2003-04-15 2011-04-13 阿奎诺克斯药物公司 作为药物活性剂的茚衍生物
US9765085B2 (en) 2013-03-14 2017-09-19 Aquinox Pharmaceuticals (Canada) Inc. SHIP1 modulators and methods related thereto
US9944590B2 (en) 2015-06-26 2018-04-17 Aquinox Pharmaceuticals (Canada) Inc. Crystalline solid forms of the acetate salt of (1S,3S,4R)-4-((3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol
US10053415B2 (en) 2016-01-20 2018-08-21 Aquinox Pharmaceuticals (Canada) Inc. Synthesis of a substituted indene derivative
US10100056B2 (en) 2013-03-14 2018-10-16 Aquinox Pharmaceuticals (Canada) Inc. SHIP1 modulators and methods related thereto

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5530487U (no) * 1978-08-18 1980-02-27
JPS63143813U (no) * 1987-03-13 1988-09-21

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2886589A (en) * 1957-08-05 1959-05-12 Merck & Co Inc 8-methyl-5-oxyphenyl hexahydroindan compounds
JPS5121981B1 (no) * 1967-09-11 1976-07-06

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0061308A1 (en) * 1981-03-19 1982-09-29 Takeda Chemical Industries, Ltd. Indancarboxylic acid zinc salts and production thereof
CN102010298A (zh) * 2003-04-15 2011-04-13 阿奎诺克斯药物公司 作为药物活性剂的茚衍生物
EP3156387A1 (en) * 2003-04-15 2017-04-19 Aquinox Pharmaceuticals (Canada) Inc. Indene derivatives as pharmaceutical agents
US9765085B2 (en) 2013-03-14 2017-09-19 Aquinox Pharmaceuticals (Canada) Inc. SHIP1 modulators and methods related thereto
US10100056B2 (en) 2013-03-14 2018-10-16 Aquinox Pharmaceuticals (Canada) Inc. SHIP1 modulators and methods related thereto
US10174046B2 (en) 2013-03-14 2019-01-08 Aquinox Pharmaceuticals (Canada) Inc. SHIP1 modulators and methods related thereto
US9944590B2 (en) 2015-06-26 2018-04-17 Aquinox Pharmaceuticals (Canada) Inc. Crystalline solid forms of the acetate salt of (1S,3S,4R)-4-((3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1H-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol
US10065920B2 (en) 2015-06-26 2018-09-04 Aquinox Pharmaceuticals (Canada) Inc. Crystalline solid forms of the acetate salt of (1S,3S,4R)-4-((3AS,4R,5S,7AS)-4-(aminomethyl)-7A-methyl-1-methyleneoctahydro-1H-inden-5-YL)-3- (hydroxymethyl)-4-methylcyclohexanol
US10053415B2 (en) 2016-01-20 2018-08-21 Aquinox Pharmaceuticals (Canada) Inc. Synthesis of a substituted indene derivative

Also Published As

Publication number Publication date
DE2004038A1 (de) 1970-08-06
DE2004038B2 (de) 1981-07-23
ES376067A1 (es) 1972-05-16
YU34270B (en) 1979-04-30
JPS5136271B1 (no) 1976-10-07
SE345995B (no) 1972-06-19
NL7001380A (no) 1970-08-04
DK130582C (no) 1975-08-18
CH565132A5 (no) 1975-08-15
CH544055A (de) 1973-11-15
NL165930B (nl) 1981-01-15
YU21170A (en) 1978-10-31
FR2034514A1 (no) 1970-12-11
DE2004038C3 (de) 1982-03-25
FR2034514B1 (no) 1973-07-13
JPS4925662B1 (no) 1974-07-02
NL165930C (nl) 1981-06-15
DK130582B (da) 1975-03-10
BE745177A (fr) 1970-07-29

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Legal Events

Date Code Title Description
PS Patent sealed
PCNP Patent ceased through non-payment of renewal fee