ES349732A1 - Substituted piperidines - Google Patents

Substituted piperidines

Info

Publication number
ES349732A1
ES349732A1 ES349732A ES349732A ES349732A1 ES 349732 A1 ES349732 A1 ES 349732A1 ES 349732 A ES349732 A ES 349732A ES 349732 A ES349732 A ES 349732A ES 349732 A1 ES349732 A1 ES 349732A1
Authority
ES
Spain
Prior art keywords
compounds
skeletal formula
defined above
skeletal
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES349732A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES349732A1 publication Critical patent/ES349732A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Novel compounds of the skeletal formula wherein R 1 is an alkyl group with 1-3 carbon atoms, R 2 represents a hydrogen, chlorine, or bromine atom or a methyl or methoxy group, are prepared by reacting compounds of the skeletal formula in which R 1 is as defined above, with a 4-chlorobutyrophenone of skeletal formula in which R 2 is as defined above, to produce the desired compounds, which, if desired, can then be converted into the acid addition salts thereof. Pharmaceutical compositions containing the above compounds which show a strong analgesic activity without a substantial addictive effect, are administered orally, rectally or parenterally.
ES349732A 1967-01-26 1968-01-25 Substituted piperidines Expired ES349732A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0090912 1967-01-26

Publications (1)

Publication Number Publication Date
ES349732A1 true ES349732A1 (en) 1969-11-01

Family

ID=6985550

Family Applications (1)

Application Number Title Priority Date Filing Date
ES349732A Expired ES349732A1 (en) 1967-01-26 1968-01-25 Substituted piperidines

Country Status (11)

Country Link
BE (1) BE709966A (en)
CH (1) CH496701A (en)
DE (1) DE1670187A1 (en)
DK (1) DK120192B (en)
ES (1) ES349732A1 (en)
FR (2) FR1568084A (en)
GB (1) GB1148427A (en)
IL (1) IL29374A (en)
NL (1) NL6800967A (en)
SE (1) SE333569B (en)
YU (1) YU18068A (en)

Also Published As

Publication number Publication date
GB1148427A (en) 1969-04-10
NL6800967A (en) 1968-07-29
DK120192B (en) 1971-04-26
FR7256M (en) 1969-09-08
CH496701A (en) 1970-09-30
YU18068A (en) 1973-10-31
IL29374A (en) 1971-07-28
FR1568084A (en) 1969-05-23
DE1670187A1 (en) 1971-01-21
BE709966A (en) 1968-07-26
SE333569B (en) 1971-03-22

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