GB1148427A - Substituted piperidines - Google Patents

Substituted piperidines

Info

Publication number
GB1148427A
GB1148427A GB431968A GB431968A GB1148427A GB 1148427 A GB1148427 A GB 1148427A GB 431968 A GB431968 A GB 431968A GB 431968 A GB431968 A GB 431968A GB 1148427 A GB1148427 A GB 1148427A
Authority
GB
United Kingdom
Prior art keywords
compounds
jan
skeletal formula
defined above
substituted piperidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB431968A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Original Assignee
CH Boehringer Sohn AG and Co KG
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG, Boehringer Ingelheim GmbH filed Critical CH Boehringer Sohn AG and Co KG
Publication of GB1148427A publication Critical patent/GB1148427A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1,148,427. Substituted piperidines. BOEHRINGER INGELHEIM G.m.b.H. 26 Jan., 1968 [26 Jan., 1967], No. 4319/68. Heading C2C. Novel compounds of the skeletal formula wherein R 1 is an alkyl group with 1-3 carbon atoms, R 2 represents a hydrogen, chlorine, or bromine atom or a methyl or methoxy group, are prepared by reacting compounds of the skeletal formula in which R 1 is as defined above, with a 4-chlorobutyrophenone of skeletal formula in which R 2 is as defined above, to produce the desired compounds, which, if desired, can then be converted into the acid addition salts thereof. Pharmaceutical compositions containing the above compounds which show a strong analgesic activity without a substantial addictive effect, are administered orally, rectally or parenterally.
GB431968A 1967-01-26 1968-01-26 Substituted piperidines Expired GB1148427A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0090912 1967-01-26

Publications (1)

Publication Number Publication Date
GB1148427A true GB1148427A (en) 1969-04-10

Family

ID=6985550

Family Applications (1)

Application Number Title Priority Date Filing Date
GB431968A Expired GB1148427A (en) 1967-01-26 1968-01-26 Substituted piperidines

Country Status (11)

Country Link
BE (1) BE709966A (en)
CH (1) CH496701A (en)
DE (1) DE1670187A1 (en)
DK (1) DK120192B (en)
ES (1) ES349732A1 (en)
FR (2) FR7256M (en)
GB (1) GB1148427A (en)
IL (1) IL29374A (en)
NL (1) NL6800967A (en)
SE (1) SE333569B (en)
YU (1) YU18068A (en)

Also Published As

Publication number Publication date
YU18068A (en) 1973-10-31
FR1568084A (en) 1969-05-23
BE709966A (en) 1968-07-26
DK120192B (en) 1971-04-26
SE333569B (en) 1971-03-22
ES349732A1 (en) 1969-11-01
FR7256M (en) 1969-09-08
CH496701A (en) 1970-09-30
IL29374A (en) 1971-07-28
NL6800967A (en) 1968-07-29
DE1670187A1 (en) 1971-01-21

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