GB1203040A - 5-nitro-2-furyl-isoxazoles and compositions thereof - Google Patents
5-nitro-2-furyl-isoxazoles and compositions thereofInfo
- Publication number
- GB1203040A GB1203040A GB7289/67A GB728967A GB1203040A GB 1203040 A GB1203040 A GB 1203040A GB 7289/67 A GB7289/67 A GB 7289/67A GB 728967 A GB728967 A GB 728967A GB 1203040 A GB1203040 A GB 1203040A
- Authority
- GB
- United Kingdom
- Prior art keywords
- furyl
- nitro
- isoxazoles
- formula
- nitrofuryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
1,203,040. Nitrofuryl-isoxazoles. J. R. GEIGY A.G. 14 Feb., 1968 [15 Feb., 1967], No. 7289/67. Heading C2C. [Also in Division A5] Nitrofuryl-isoxazoles of Formula I, and their tautomers of Formulµ Ia and Ib, in which each of R 1 and R 2 is aC 1-4 alkyl group which is unsubstituted or hydroxy-, alkoxy- or halogensubstituted, C 3-4 alkenyl, C 5-6 cycloalkyi or C 1-4 alkoxy-carbonyl, or in which R 1 is C 3-4 alkenyl and R 2 is hydrogen, are prepared by reacting a reactive functional derivative of a carboxylic acid of Formula II with a compound of Formula III or with a derivative capable of producing a compound of Formula III under the reaction conditions. The compounds in which R 2 is not hydrogen are novel. 3 - (5 - Nitro - 2 - -furyl) - 4 - chlorocarbonyl - 5- amino-isoxazole is prepared by hydrolysing 3- (5 - nitro - 2 - furyl) - 4 - tert. - butoxycarbonyl- 5-amino-isoxazole and reacting the resulting 3 (5 - nitro - 2 - furyl) - 4 - carboxy - 5 - aminoisoxazole with thienyl chloride.
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7288/67A GB1203039A (en) | 1967-02-15 | 1967-02-15 | Process for the production of nitrofuryl derivatives |
GB7289/67A GB1203040A (en) | 1967-02-15 | 1967-02-15 | 5-nitro-2-furyl-isoxazoles and compositions thereof |
US704570A US3562286A (en) | 1967-02-15 | 1968-02-12 | Nitrofuryl isoxazole derivatives |
CH212668A CH494769A (en) | 1967-02-15 | 1968-02-13 | Process for the preparation of new 5-nitrofuryl derivatives |
AT140368A AT275508B (en) | 1967-02-15 | 1968-02-14 | Process for the preparation of new 3- (5-nitro-2-furyl) isoxazole derivatives |
BE710795D BE710795A (en) | 1967-02-15 | 1968-02-14 | |
FR1584727D FR1584727A (en) | 1967-02-15 | 1968-02-14 | |
NL6802101A NL6802101A (en) | 1967-02-15 | 1968-02-14 | |
ES350491A ES350491A1 (en) | 1967-02-15 | 1968-02-14 | Procedure for the preparation of derivatives of 5-nitro-2-furil-isoxazoles. (Machine-translation by Google Translate, not legally binding) |
FR151373A FR7882M (en) | 1967-02-15 | 1968-05-10 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7288/67A GB1203039A (en) | 1967-02-15 | 1967-02-15 | Process for the production of nitrofuryl derivatives |
GB7289/67A GB1203040A (en) | 1967-02-15 | 1967-02-15 | 5-nitro-2-furyl-isoxazoles and compositions thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1203040A true GB1203040A (en) | 1970-08-26 |
Family
ID=26241317
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7288/67A Expired GB1203039A (en) | 1967-02-15 | 1967-02-15 | Process for the production of nitrofuryl derivatives |
GB7289/67A Expired GB1203040A (en) | 1967-02-15 | 1967-02-15 | 5-nitro-2-furyl-isoxazoles and compositions thereof |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB7288/67A Expired GB1203039A (en) | 1967-02-15 | 1967-02-15 | Process for the production of nitrofuryl derivatives |
Country Status (6)
Country | Link |
---|---|
US (1) | US3562286A (en) |
BE (1) | BE710795A (en) |
CH (1) | CH494769A (en) |
FR (2) | FR1584727A (en) |
GB (2) | GB1203039A (en) |
NL (1) | NL6802101A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005113519A1 (en) * | 2004-05-14 | 2005-12-01 | Irm Llc | Compounds and compositions as ppar modulators |
-
1967
- 1967-02-15 GB GB7288/67A patent/GB1203039A/en not_active Expired
- 1967-02-15 GB GB7289/67A patent/GB1203040A/en not_active Expired
-
1968
- 1968-02-12 US US704570A patent/US3562286A/en not_active Expired - Lifetime
- 1968-02-13 CH CH212668A patent/CH494769A/en not_active IP Right Cessation
- 1968-02-14 FR FR1584727D patent/FR1584727A/fr not_active Expired
- 1968-02-14 NL NL6802101A patent/NL6802101A/xx unknown
- 1968-02-14 BE BE710795D patent/BE710795A/xx unknown
- 1968-05-10 FR FR151373A patent/FR7882M/fr not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR1584727A (en) | 1970-01-02 |
CH494769A (en) | 1970-08-15 |
NL6802101A (en) | 1968-08-16 |
BE710795A (en) | 1968-08-14 |
US3562286A (en) | 1971-02-09 |
GB1203039A (en) | 1970-08-26 |
FR7882M (en) | 1970-05-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] |