ES340412A1 - Procedimiento para la preparacion de derivados de piroin- dol. - Google Patents

Procedimiento para la preparacion de derivados de piroin- dol.

Info

Publication number
ES340412A1
ES340412A1 ES340412A ES340412A ES340412A1 ES 340412 A1 ES340412 A1 ES 340412A1 ES 340412 A ES340412 A ES 340412A ES 340412 A ES340412 A ES 340412A ES 340412 A1 ES340412 A1 ES 340412A1
Authority
ES
Spain
Prior art keywords
alkyl
formula
acid addition
addition salts
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES340412A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES340412A1 publication Critical patent/ES340412A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/42Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
ES340412A 1966-05-12 1967-05-11 Procedimiento para la preparacion de derivados de piroin- dol. Expired ES340412A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54945566A 1966-05-12 1966-05-12
US628530A US3409628A (en) 1966-05-12 1967-04-05 5-(3-pyridylethyl)pyridoindole derivatives

Publications (1)

Publication Number Publication Date
ES340412A1 true ES340412A1 (es) 1968-06-01

Family

ID=27069138

Family Applications (1)

Application Number Title Priority Date Filing Date
ES340412A Expired ES340412A1 (es) 1966-05-12 1967-05-11 Procedimiento para la preparacion de derivados de piroin- dol.

Country Status (14)

Country Link
US (1) US3409628A (es)
BE (1) BE698183A (es)
CH (1) CH494234A (es)
DE (1) DE1695187A1 (es)
DK (1) DK123655B (es)
ES (1) ES340412A1 (es)
FI (1) FI48093C (es)
FR (2) FR1522686A (es)
GB (3) GB1173997A (es)
IL (1) IL27956A (es)
NL (1) NL6706671A (es)
NO (1) NO123950B (es)
SE (1) SE342231B (es)
YU (1) YU94367A (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696930A (en) * 1985-04-12 1987-09-29 Hoffmann-La Roche Inc. N-(heteroarylalkyl)acylanilide derivatives as antiarrhythmic agents
RU2339637C1 (ru) * 2007-04-05 2008-11-27 Андрей Александрович Иващенко Блокаторы гистаминного рецептора для фармацевтических композиций, обладающих противоаллергическим и аутоиммунным действием
MX2010003149A (es) * 2007-09-20 2010-11-10 D2E Llc Derivados que contienen fluor de pirido[4,3-b]indoles hidrogenados con propiedades neuroprotectoras y de mejoramiento de cognicion, proceso de preparacion y uso.
RU2007139634A (ru) 2007-10-25 2009-04-27 Сергей Олегович Бачурин (RU) Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения
WO2009082268A2 (ru) * 2007-12-21 2009-07-02 Alla Chem, Llc ЛИГАНДЫ α-АДРЕНОЦЕПТОРОВ, ДОПАМИНОВЫХ, ГИСТАМИНОВЫХ, ИМИДАЗОЛИНОВЫХ И СЕРОТОНИНОВЫХ РЕЦЕПТОРОВ И ИХ ПРИМЕНЕНИЕ
TW201018694A (en) * 2008-09-29 2010-05-16 Abbott Lab Indole and indoline derivatives and methods of use thereof
US9625475B2 (en) * 2008-09-29 2017-04-18 Abbvie Inc. Indole and indoline derivatives and methods of use thereof
US8703952B2 (en) 2008-12-12 2014-04-22 Wista Laboratories Ltd. Synthesis of 9-(arylalkyl)-1,2,3,4-tetrahydro-γ-carboline and analogues and intermediates
EP2385829B1 (en) * 2009-01-09 2018-08-01 Board of Regents of the University of Texas System Pro-neurogenic compounds
US9962368B2 (en) 2009-01-09 2018-05-08 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US8362277B2 (en) 2009-01-09 2013-01-29 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
US9162980B2 (en) 2009-01-09 2015-10-20 Board Of Regents Of The University Of Texas System Anti-depression compounds
WO2011019417A1 (en) 2009-04-29 2011-02-17 Medivation Technologies, Inc. Pyrido [4, 3-b] indoles and methods of use
CN102480955B (zh) 2009-04-29 2015-08-05 梅迪维新技术公司 吡啶并[4,3-b]吲哚类和使用方法
WO2011008312A2 (en) 2009-07-14 2011-01-20 Abbott Laboratories Indole and indoline derivatives and methods of use thereof
AU2011274787B2 (en) 2010-07-07 2016-06-16 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
JP2014505737A (ja) 2011-02-18 2014-03-06 メディベイション テクノロジーズ, インコーポレイテッド 糖尿病を処置する化合物および方法
US9701676B2 (en) 2012-08-24 2017-07-11 Board Of Regents Of The University Of Texas System Pro-neurogenic compounds
WO2015070237A1 (en) 2013-11-11 2015-05-14 Board Of Regents Of The University Of Texas System Neuroprotective chemicals and methods for identifying and using same
EP3068388A4 (en) 2013-11-11 2017-04-12 Board of Regents of the University of Texas System Neuroprotective compounds and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2786059A (en) * 1951-04-30 1957-03-19 Schenley Ind Inc Derivatives of 2-nu-methyl-1, 2, 3, 4-tetrahydro-gamma-carbolines

Also Published As

Publication number Publication date
FI48093C (fi) 1974-06-10
DE1695187A1 (de) 1971-04-08
FR7024M (es) 1969-06-09
GB1173997A (en) 1969-12-10
FR1522686A (fr) 1968-04-26
GB1173999A (en) 1969-12-10
YU94367A (en) 1974-08-31
NL6706671A (es) 1967-11-13
US3409628A (en) 1968-11-05
BE698183A (es) 1967-11-09
CH494234A (de) 1970-07-31
FI48093B (es) 1974-02-28
GB1173998A (en) 1969-12-10
SE342231B (es) 1972-01-31
DK123655B (da) 1972-07-17
NO123950B (es) 1972-02-07
IL27956A (en) 1972-06-28

Similar Documents

Publication Publication Date Title
ES340412A1 (es) Procedimiento para la preparacion de derivados de piroin- dol.
GB1172034A (en) Substituted 3-Ureidopyrrolidines
GB1250208A (es)
GB1085672A (en) Substituted phthalazines
ES350752A1 (es) Un procedimiento de preparacion de nuevas cloroquinoleinas.
GB1167711A (en) Diarylcyclopropane Derivatives
GB1336913A (en) Indolyl acetic acid derivatives processes for producing them and compositions containing them
ES428673A1 (es) Procedimiento para la obtencion de derivados de nitrobenzo-fenona sustituidos.
GB1246117A (en) Pharmaceutical preparations containing glucose compounds, glucose derivatives and process for their manufacture
GB1317838A (en) Pyridoindole derivatives
ES348125A1 (es) Procedimiento para la preparacion de derivados indolicos.
GB1245155A (en) NOVEL 5-SUBSTITUTED-gamma-CARBOLINE DERIVATIVES AND THE SALTS THEREOF
ES353670A1 (es) Procedimiento para la produccion de nuevos 1 - fenoxi-3-al-cohilaminopropanoles-(2) sustituidos.
GB1158530A (en) Ergoline Derivatives
GB1218590A (en) N-substituted piperidine spiro compounds
ES369304A1 (es) Procedimiento de preparacion de nuevos derivados nitrogena-dos de la metil-2 benzil-3 imidazo-3h (4,5-b) piridina.
GB1131126A (en) 2-vinyl-1,4-dihydroquinazoline derivatives
GB1074744A (en) Improvements in or relating to substituted 9,10-dihydro-4h-benzo[4,5]cyclo-hepta[1,2-b]thiophenes
GB1321691A (en) Dihydro-3-piperidyl-2 3h-furanone derivatives
ES336293A1 (es) Procedimiento para preparar eteres de benzociclohepta-tio- feno.
GB1307390A (en) Benzodioxanes
GB1346456A (en) Organic acid 2,6-disubstituted phenyl hydrazides
GB1069716A (en) Improvements in or relating to pyrido[3,4-b]indole derivatives
ES340846A1 (es) Procedimiento de preparacion del compuesto 3,5,3'-triiodo- tiroacetato de reserpina.
GB1113968A (en) Tetrahydropyridazines and their preparation