ES340846A1 - Procedimiento de preparacion del compuesto 3,5,3'-triiodo- tiroacetato de reserpina. - Google Patents
Procedimiento de preparacion del compuesto 3,5,3'-triiodo- tiroacetato de reserpina.Info
- Publication number
- ES340846A1 ES340846A1 ES340846A ES340846A ES340846A1 ES 340846 A1 ES340846 A1 ES 340846A1 ES 340846 A ES340846 A ES 340846A ES 340846 A ES340846 A ES 340846A ES 340846 A1 ES340846 A1 ES 340846A1
- Authority
- ES
- Spain
- Prior art keywords
- reserpine
- triiodothyroacetate
- antiselerous
- antiatheromatous
- hypotensive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- DNXIKVLOVZVMQF-UHFFFAOYSA-N (3beta,16beta,17alpha,18beta,20alpha)-17-hydroxy-11-methoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(C(=O)OC)C(O)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 DNXIKVLOVZVMQF-UHFFFAOYSA-N 0.000 title abstract 3
- LCQMZZCPPSWADO-UHFFFAOYSA-N Reserpilin Natural products COC(=O)C1COCC2CN3CCc4c([nH]c5cc(OC)c(OC)cc45)C3CC12 LCQMZZCPPSWADO-UHFFFAOYSA-N 0.000 title abstract 3
- QEVHRUUCFGRFIF-SFWBKIHZSA-N Reserpine Natural products O=C(OC)[C@@H]1[C@H](OC)[C@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)C[C@H]2[C@@H]1C[C@H]1N(C2)CCc2c3c([nH]c12)cc(OC)cc3 QEVHRUUCFGRFIF-SFWBKIHZSA-N 0.000 title abstract 3
- BJOIZNZVOZKDIG-MDEJGZGSSA-N reserpine Chemical compound O([C@H]1[C@@H]([C@H]([C@H]2C[C@@H]3C4=C([C]5C=CC(OC)=CC5=N4)CCN3C[C@H]2C1)C(=O)OC)OC)C(=O)C1=CC(OC)=C(OC)C(OC)=C1 BJOIZNZVOZKDIG-MDEJGZGSSA-N 0.000 title abstract 3
- 229960003147 reserpine Drugs 0.000 title abstract 3
- MDMGHDFNKNZPAU-UHFFFAOYSA-N roserpine Natural products C1C2CN3CCC(C4=CC=C(OC)C=C4N4)=C4C3CC2C(OC(C)=O)C(OC)C1OC(=O)C1=CC(OC)=C(OC)C(OC)=C1 MDMGHDFNKNZPAU-UHFFFAOYSA-N 0.000 title abstract 3
- UOWZUVNAGUAEQC-UHFFFAOYSA-N tiratricol Chemical compound IC1=CC(CC(=O)O)=CC(I)=C1OC1=CC=C(O)C(I)=C1 UOWZUVNAGUAEQC-UHFFFAOYSA-N 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000000879 anti-atherosclerotic effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D459/00—Heterocyclic compounds containing benz [g] indolo [2, 3-a] quinolizine ring systems, e.g. yohimbine; 16, 18-lactones thereof, e.g. reserpic acid lactone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR63270A FR5821M (es) | 1966-05-27 | 1966-05-27 | |
| FR106044A FR1529878A (fr) | 1967-05-11 | 1967-05-11 | Procédé de préparation du 3, 5, 3'-triiodothyroacétate de réserpine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES340846A1 true ES340846A1 (es) | 1968-06-16 |
Family
ID=26170947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES340846A Expired ES340846A1 (es) | 1966-05-27 | 1967-05-22 | Procedimiento de preparacion del compuesto 3,5,3'-triiodo- tiroacetato de reserpina. |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US3484442A (es) |
| BE (1) | BE698982A (es) |
| DE (1) | DE1670628A1 (es) |
| ES (1) | ES340846A1 (es) |
| GB (1) | GB1167407A (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1445500A1 (de) * | 1963-06-07 | 1968-12-05 | Boehringer & Soehne Gmbh | Verfahren zur Herstellung neuer Yohimban-Derivate und deren Salze |
-
1967
- 1967-05-22 ES ES340846A patent/ES340846A1/es not_active Expired
- 1967-05-23 GB GB23930/67A patent/GB1167407A/en not_active Expired
- 1967-05-25 BE BE698982D patent/BE698982A/xx unknown
- 1967-05-26 US US641452A patent/US3484442A/en not_active Expired - Lifetime
- 1967-05-26 DE DE19671670628 patent/DE1670628A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US3484442A (en) | 1969-12-16 |
| BE698982A (es) | 1967-11-27 |
| GB1167407A (en) | 1969-10-15 |
| DE1670628A1 (de) | 1971-02-11 |
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