GB1173985A - Indole Derivatives - Google Patents

Indole Derivatives

Info

Publication number
GB1173985A
GB1173985A GB4451367A GB4451367A GB1173985A GB 1173985 A GB1173985 A GB 1173985A GB 4451367 A GB4451367 A GB 4451367A GB 4451367 A GB4451367 A GB 4451367A GB 1173985 A GB1173985 A GB 1173985A
Authority
GB
United Kingdom
Prior art keywords
compositions
indole derivatives
inflammatory
chlorobenzoyl
merck
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4451367A
Inventor
Meyer Sletzinger
George Gal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1173985A publication Critical patent/GB1173985A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/72—Hydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/38—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Abstract

1,173,985. Anti-inflammatory compositions. MERCK & CO. Inc. 29 Sept., 1967 [3 Oct., 1966], No. 44513/67. Heading A5B. [Also in Division C2] Pharmaceutical compositions having anti-inflammatory activity comprise, as active ingredient, 1-p-chlorobenzoyl-2-methyl-5-dimethylamino-3-indolylacetic acid of the general formula: The compositions may be administered orally as capsules or tablets.
GB4451367A 1966-10-03 1967-09-29 Indole Derivatives Expired GB1173985A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US58396766A 1966-10-03 1966-10-03

Publications (1)

Publication Number Publication Date
GB1173985A true GB1173985A (en) 1969-12-10

Family

ID=24335355

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4451367A Expired GB1173985A (en) 1966-10-03 1967-09-29 Indole Derivatives

Country Status (8)

Country Link
AT (2) AT290495B (en)
DE (1) DE1668411A1 (en)
ES (1) ES345583A1 (en)
GB (1) GB1173985A (en)
GR (1) GR34666B (en)
NL (1) NL6713450A (en)
SE (1) SE328578B (en)
YU (1) YU34513B (en)

Also Published As

Publication number Publication date
ES345583A1 (en) 1970-02-01
NL6713450A (en) 1968-04-04
SE328578B (en) 1970-09-21
AT282618B (en) 1970-07-10
DE1668411A1 (en) 1971-06-03
GR34666B (en) 1968-06-05
YU34513B (en) 1979-09-10
YU314370A (en) 1979-02-28
AT290495B (en) 1971-06-11

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees