ES3040534T3 - Modulator of sestrin-gator2 interaction for use in the treatment of treatment-resistant depression - Google Patents

Modulator of sestrin-gator2 interaction for use in the treatment of treatment-resistant depression

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Publication number
ES3040534T3
ES3040534T3 ES18791427T ES18791427T ES3040534T3 ES 3040534 T3 ES3040534 T3 ES 3040534T3 ES 18791427 T ES18791427 T ES 18791427T ES 18791427 T ES18791427 T ES 18791427T ES 3040534 T3 ES3040534 T3 ES 3040534T3
Authority
ES
Spain
Prior art keywords
mmol
acid
solution
mixture
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES18791427T
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English (en)
Spanish (es)
Inventor
Eddine Saiah
George Vlasuk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Navitor Pharmaceuticals Inc
Original Assignee
Navitor Pharmaceuticals Inc
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Publication date
Application filed by Navitor Pharmaceuticals Inc filed Critical Navitor Pharmaceuticals Inc
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Publication of ES3040534T3 publication Critical patent/ES3040534T3/es
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • A61K31/13—Amines
    • A61K31/133—Amines having hydroxy groups, e.g. sphingosine
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    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/136—Amines having aromatic rings, e.g. ketamine, nortriptyline having the amino group directly attached to the aromatic ring, e.g. benzeneamine
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    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
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    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Optical Modulation, Optical Deflection, Nonlinear Optics, Optical Demodulation, Optical Logic Elements (AREA)
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ES18791427T 2017-04-26 2018-04-25 Modulator of sestrin-gator2 interaction for use in the treatment of treatment-resistant depression Active ES3040534T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762490280P 2017-04-26 2017-04-26
PCT/US2018/029288 WO2018200625A1 (en) 2017-04-26 2018-04-25 Modulators of sestrin-gator2 interaction and uses thereof

Publications (1)

Publication Number Publication Date
ES3040534T3 true ES3040534T3 (en) 2025-11-03

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ES18791427T Active ES3040534T3 (en) 2017-04-26 2018-04-25 Modulator of sestrin-gator2 interaction for use in the treatment of treatment-resistant depression

Country Status (10)

Country Link
US (4) US10912750B2 (https=)
EP (2) EP4556069A3 (https=)
JP (1) JP7179015B2 (https=)
CN (2) CN110809467B (https=)
AU (2) AU2018258355B2 (https=)
CA (1) CA3061611A1 (https=)
ES (1) ES3040534T3 (https=)
PL (1) PL3615019T3 (https=)
TW (1) TWI776886B (https=)
WO (1) WO2018200625A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE061437T2 (hu) 2015-10-23 2023-06-28 Navitor Pharm Inc A Sestrin-GATOR2 kölcsönhatás modulátorai és ezek alkalmazásai
US10912750B2 (en) 2017-04-26 2021-02-09 Navitor Pharmaceuticals, Inc. Modulators of Sestrin-GATOR2 interaction and uses thereof
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