ES2996232T3 - Method for the production of immunoglobulin single variable domains - Google Patents
Method for the production of immunoglobulin single variable domains Download PDFInfo
- Publication number
- ES2996232T3 ES2996232T3 ES17192342T ES17192342T ES2996232T3 ES 2996232 T3 ES2996232 T3 ES 2996232T3 ES 17192342 T ES17192342 T ES 17192342T ES 17192342 T ES17192342 T ES 17192342T ES 2996232 T3 ES2996232 T3 ES 2996232T3
- Authority
- ES
- Spain
- Prior art keywords
- single variable
- immunoglobulin single
- variable domain
- host
- nanobody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40822810P | 2010-10-29 | 2010-10-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2996232T3 true ES2996232T3 (en) | 2025-02-12 |
Family
ID=44872371
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES17192342T Active ES2996232T3 (en) | 2010-10-29 | 2011-10-28 | Method for the production of immunoglobulin single variable domains |
| ES11775994.4T Active ES2660895T3 (es) | 2010-10-29 | 2011-10-28 | Método para la producción de dominios variables individuales de inmunoglobulina |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES11775994.4T Active ES2660895T3 (es) | 2010-10-29 | 2011-10-28 | Método para la producción de dominios variables individuales de inmunoglobulina |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20130261288A1 (Direct) |
| EP (3) | EP2632946B1 (Direct) |
| DK (2) | DK2632946T3 (Direct) |
| ES (2) | ES2996232T3 (Direct) |
| HU (1) | HUE069364T2 (Direct) |
| NO (1) | NO2632946T3 (Direct) |
| PL (2) | PL2632946T3 (Direct) |
| PT (1) | PT2632946T (Direct) |
| WO (1) | WO2012056000A1 (Direct) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO2632946T3 (Direct) | 2010-10-29 | 2018-05-05 | ||
| WO2014087010A1 (en) | 2012-12-07 | 2014-06-12 | Ablynx N.V. | IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE |
| KR20150122761A (ko) | 2013-02-26 | 2015-11-02 | 로슈 글리카트 아게 | Ｔ 세포 활성화 항원 결합 분자 |
| HRP20240971T1 (hr) | 2015-05-13 | 2024-10-25 | Ablynx Nv | Polipeptidi za regruitiranje t-stanica na temelju cd3 reaktivnosti |
| RS66859B1 (sr) | 2015-05-13 | 2025-06-30 | Ablynx Nv | Polipeptidi koji regrutuju t-ćelije na bazi tcr-alfa/beta reaktivnosti |
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| US20200062834A1 (en) | 2020-02-27 |
| PT2632946T (pt) | 2018-03-01 |
| HUE069364T2 (hu) | 2025-03-28 |
| DK3279214T3 (da) | 2024-12-09 |
| PL2632946T3 (pl) | 2018-06-29 |
| NO2632946T3 (Direct) | 2018-05-05 |
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| US20130261288A1 (en) | 2013-10-03 |
| EP4458858A2 (en) | 2024-11-06 |
| WO2012056000A1 (en) | 2012-05-03 |
| ES2660895T3 (es) | 2018-03-26 |
| EP4458858A3 (en) | 2025-02-19 |
| EP3279214A1 (en) | 2018-02-07 |
| EP2632946B1 (en) | 2017-12-06 |
| DK2632946T3 (en) | 2018-03-12 |
| US20200392214A9 (en) | 2020-12-17 |
| US12522652B2 (en) | 2026-01-13 |
| EP2632946A1 (en) | 2013-09-04 |
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