PT2632946T - Método para a produção de domínios variáveis únicos da imunoglobulina - Google Patents

Método para a produção de domínios variáveis únicos da imunoglobulina

Info

Publication number
PT2632946T
PT2632946T PT117759944T PT11775994T PT2632946T PT 2632946 T PT2632946 T PT 2632946T PT 117759944 T PT117759944 T PT 117759944T PT 11775994 T PT11775994 T PT 11775994T PT 2632946 T PT2632946 T PT 2632946T
Authority
PT
Portugal
Prior art keywords
production
variable domains
single variable
immunoglobulin single
immunoglobulin
Prior art date
Application number
PT117759944T
Other languages
English (en)
Inventor
Brige Ann
Walcarius Bart
Meyvis Yves
Sergi Mauro
Original Assignee
Ablynx Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44872371&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2632946(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ablynx Nv filed Critical Ablynx Nv
Publication of PT2632946T publication Critical patent/PT2632946T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
PT117759944T 2010-10-29 2011-10-28 Método para a produção de domínios variáveis únicos da imunoglobulina PT2632946T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40822810P 2010-10-29 2010-10-29

Publications (1)

Publication Number Publication Date
PT2632946T true PT2632946T (pt) 2018-03-01

Family

ID=44872371

Family Applications (1)

Application Number Title Priority Date Filing Date
PT117759944T PT2632946T (pt) 2010-10-29 2011-10-28 Método para a produção de domínios variáveis únicos da imunoglobulina

Country Status (8)

Country Link
US (2) US20130261288A1 (pt)
EP (2) EP2632946B1 (pt)
DK (1) DK2632946T3 (pt)
ES (1) ES2660895T3 (pt)
NO (1) NO2632946T3 (pt)
PL (1) PL2632946T3 (pt)
PT (1) PT2632946T (pt)
WO (1) WO2012056000A1 (pt)

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NO2632946T3 (pt) 2010-10-29 2018-05-05
WO2014087010A1 (en) 2012-12-07 2014-06-12 Ablynx N.V. IMPROVED POLYPEPTIDES DIRECTED AGAINST IgE
CA2896370A1 (en) 2013-02-26 2014-09-04 Roche Glycart Ag Bispecific t cell activating antigen binding molecules
ES2754427T3 (es) 2015-05-13 2020-04-17 Ablynx Nv Polipéptidos de reclutamiento de células T basados en la reactividad de TCR alfa/beta
CN114920847A (zh) 2015-05-13 2022-08-19 埃博灵克斯股份有限公司 基于cd3反应性的t细胞募集多肽
US11840569B2 (en) 2016-11-16 2023-12-12 Ablynx N.V. T cell recruiting polypeptides capable of binding CD123 and TCR alpha/beta
JP2023519967A (ja) 2020-03-30 2023-05-15 アブリンクス・エヌ・フェー 多価免疫グロブリン単一可変ドメインの製造及び精製のための方法
TW202241948A (zh) 2020-12-18 2022-11-01 比利時商艾伯霖克斯公司 基於TCR α/β反應性的T細胞募集多肽
WO2024023271A1 (en) 2022-07-27 2024-02-01 Ablynx Nv Polypeptides binding to a specific epitope of the neonatal fc receptor

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MX2010005783A (es) 2007-11-27 2010-08-10 Ablynx Nv Secuencias de aminoacidos dirigidas contra citoquinas heterodimericas y/o sus receptores y polipeptidos que comprenden las mismas.
US10118962B2 (en) 2008-10-29 2018-11-06 Ablynx N.V. Methods for purification of single domain antigen binding molecules
CN102388069B (zh) 2009-04-10 2016-01-20 埃博灵克斯股份有限公司 用于治疗il-6r相关疾病和病症的改进的针对il-6r的氨基酸序列和包含其的多肽
EP3828201A1 (en) 2009-04-30 2021-06-02 Ablynx N.V. Method for the production of domain antibodies
US8945567B2 (en) 2009-06-05 2015-02-03 Ablynx N.V. Monovalent, bivalent and trivalent anti human respiratory syncytial virus (HRSV) nanobody constructs for the prevention and/or treatment of respiratory tract infections
WO2011073180A1 (en) 2009-12-14 2011-06-23 Ablynx N.V. Single variable domain antibodies against ox40l, constructs and therapeutic use
NO2632946T3 (pt) 2010-10-29 2018-05-05

Also Published As

Publication number Publication date
NO2632946T3 (pt) 2018-05-05
WO2012056000A1 (en) 2012-05-03
ES2660895T3 (es) 2018-03-26
US20130261288A1 (en) 2013-10-03
US20200392214A9 (en) 2020-12-17
US20200062834A1 (en) 2020-02-27
PL2632946T3 (pl) 2018-06-29
EP2632946A1 (en) 2013-09-04
DK2632946T3 (en) 2018-03-12
EP2632946B1 (en) 2017-12-06
EP3279214A1 (en) 2018-02-07

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