BR112012020964A2 - método de produção de imunoglobulina - Google Patents
método de produção de imunoglobulinaInfo
- Publication number
- BR112012020964A2 BR112012020964A2 BR112012020964A BR112012020964A BR112012020964A2 BR 112012020964 A2 BR112012020964 A2 BR 112012020964A2 BR 112012020964 A BR112012020964 A BR 112012020964A BR 112012020964 A BR112012020964 A BR 112012020964A BR 112012020964 A2 BR112012020964 A2 BR 112012020964A2
- Authority
- BR
- Brazil
- Prior art keywords
- production method
- immunoglobulin production
- immunoglobulin
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10156103 | 2010-03-10 | ||
PCT/EP2011/053547 WO2011110598A1 (en) | 2010-03-10 | 2011-03-09 | Method for purifying immunoglobulin solutions |
Publications (3)
Publication Number | Publication Date |
---|---|
BR112012020964A2 true BR112012020964A2 (pt) | 2016-05-03 |
BR112012020964B1 BR112012020964B1 (pt) | 2021-02-23 |
BR112012020964B8 BR112012020964B8 (pt) | 2021-08-24 |
Family
ID=42236585
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012020964A BR112012020964B8 (pt) | 2010-03-10 | 2011-03-09 | método para produzir uma imunoglobulina da subclasse igg1 ou igg4 |
Country Status (12)
Country | Link |
---|---|
US (4) | US9884904B2 (pt) |
EP (1) | EP2545066B1 (pt) |
JP (2) | JP5814951B2 (pt) |
KR (1) | KR101555740B1 (pt) |
CN (1) | CN102791726B (pt) |
BR (1) | BR112012020964B8 (pt) |
CA (1) | CA2789564C (pt) |
ES (1) | ES2648264T3 (pt) |
HK (1) | HK1176946A1 (pt) |
MX (1) | MX348739B (pt) |
RU (1) | RU2558367C2 (pt) |
WO (1) | WO2011110598A1 (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9884904B2 (en) * | 2010-03-10 | 2018-02-06 | Hoffmann-La Roche Inc. | Method for purifying polypeptide solutions |
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
SG10201605397PA (en) | 2011-07-01 | 2016-08-30 | Hoffmann La Roche | Method For Separation Of Monomeric Polypeptides From Aggregated Polypeptides |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158279A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Protein purification methods to reduce acidic species |
WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
US20140010820A1 (en) * | 2012-05-21 | 2014-01-09 | Abbvie, Inc. | Novel purification of non-human antibodies using protein a affinity chromatography |
US9249182B2 (en) | 2012-05-24 | 2016-02-02 | Abbvie, Inc. | Purification of antibodies using hydrophobic interaction chromatography |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
US9206390B2 (en) | 2012-09-02 | 2015-12-08 | Abbvie, Inc. | Methods to control protein heterogeneity |
WO2014143205A1 (en) | 2013-03-12 | 2014-09-18 | Abbvie Inc. | Human antibodies that bind human tnf-alpha and methods of preparing the same |
US8921526B2 (en) | 2013-03-14 | 2014-12-30 | Abbvie, Inc. | Mutated anti-TNFα antibodies and methods of their use |
WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
WO2015051293A2 (en) | 2013-10-04 | 2015-04-09 | Abbvie, Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US8946395B1 (en) | 2013-10-18 | 2015-02-03 | Abbvie Inc. | Purification of proteins using hydrophobic interaction chromatography |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
EP3118210B1 (en) | 2014-03-11 | 2019-11-13 | Green Cross Holdings Corporation | Method for purifying immunoglobulin |
CN107108720A (zh) | 2014-11-06 | 2017-08-29 | 豪夫迈·罗氏有限公司 | 具有改变的FCRN结合的Fc区变体及其使用方法 |
CN111378030A (zh) * | 2018-12-29 | 2020-07-07 | 中国科学院青岛生物能源与过程研究所 | 一种纳米抗体分离纯化的方法 |
EP4054629A2 (en) * | 2019-11-07 | 2022-09-14 | Janssen Vaccines & Prevention B.V. | Protein purification |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5196323A (en) | 1985-04-27 | 1993-03-23 | Boehringer Ingelheim International Gmbh | Process for preparing and purifying alpha-interferon |
IL118069A (en) * | 1995-05-02 | 2000-06-01 | Japan Tobacco Inc | Monoclonal antibody reactive to human CETP and assay method for human CETP |
DE10037781A1 (de) * | 2000-08-03 | 2002-02-21 | Agfa Gevaert Ag | Vorrichtung und Verfahren zum Beschreiben von Aufzeichnungsmaterial mit Bildinformationen |
ES2184594B1 (es) * | 2001-01-17 | 2004-01-01 | Probitas Pharma Sa | Procedimiento para la produccion de gammaglobulina g humana inactivada de virus. |
EP2336149A1 (en) | 2001-03-09 | 2011-06-22 | Chugai Seiyaku Kabushiki Kaisha | Protein purification method |
HUE027134T2 (en) * | 2002-09-11 | 2016-10-28 | Chugai Pharmaceutical Co Ltd | Method for protein purification |
ZA200504990B (en) * | 2003-01-09 | 2006-08-30 | Genentech Inc | Purification of polypeptides |
PT1737891E (pt) | 2004-04-13 | 2013-04-16 | Hoffmann La Roche | Anticorpos anti p-selectina |
ES2565481T3 (es) | 2005-03-24 | 2016-04-05 | Thrombogenics N.V. | Anticuerpo anti-PlGF novedoso |
TWI391399B (zh) | 2005-05-25 | 2013-04-01 | Hoffmann La Roche | 測定溶離多肽之鹽濃度之方法 |
EP1896504B1 (en) * | 2005-06-17 | 2012-11-21 | Wyeth LLC | Methods of purifying fc region containing antibodies |
AR062223A1 (es) | 2006-08-09 | 2008-10-22 | Glycart Biotechnology Ag | Moleculas de adhesion al antigeno que se adhieren a egfr, vectores que los codifican, y sus usos de estas |
US9109015B2 (en) | 2006-11-01 | 2015-08-18 | Biogen Ma Inc | Method of isolating biomacromolecules using low pH and divalent cations |
BRPI0812288A2 (pt) | 2007-06-01 | 2014-11-25 | Hoffmann La Roche | Purificação de imunoglobulina. |
GB0818228D0 (en) | 2008-10-06 | 2008-11-12 | Avecia Biolog Ltd | Purification process |
AU2010335282B2 (en) | 2009-12-22 | 2015-05-21 | Roche Glycart Ag | Anti-HER3 antibodies and uses thereof |
US9884904B2 (en) * | 2010-03-10 | 2018-02-06 | Hoffmann-La Roche Inc. | Method for purifying polypeptide solutions |
SG10201605397PA (en) | 2011-07-01 | 2016-08-30 | Hoffmann La Roche | Method For Separation Of Monomeric Polypeptides From Aggregated Polypeptides |
-
2011
- 2011-03-09 US US13/582,606 patent/US9884904B2/en active Active
- 2011-03-09 RU RU2012141149/04A patent/RU2558367C2/ru active
- 2011-03-09 CA CA2789564A patent/CA2789564C/en active Active
- 2011-03-09 JP JP2012556507A patent/JP5814951B2/ja active Active
- 2011-03-09 CN CN201180013130.3A patent/CN102791726B/zh active Active
- 2011-03-09 WO PCT/EP2011/053547 patent/WO2011110598A1/en active Application Filing
- 2011-03-09 MX MX2012009892A patent/MX348739B/es active IP Right Grant
- 2011-03-09 EP EP11707416.1A patent/EP2545066B1/en active Active
- 2011-03-09 BR BR112012020964A patent/BR112012020964B8/pt active Search and Examination
- 2011-03-09 ES ES11707416.1T patent/ES2648264T3/es active Active
- 2011-03-09 KR KR1020127022486A patent/KR101555740B1/ko active IP Right Grant
-
2013
- 2013-04-09 HK HK13104287.9A patent/HK1176946A1/zh unknown
-
2015
- 2015-07-01 JP JP2015132573A patent/JP5931255B2/ja active Active
-
2018
- 2018-02-02 US US15/887,894 patent/US20190010216A1/en not_active Abandoned
-
2019
- 2019-12-19 US US16/721,317 patent/US20200231655A1/en not_active Abandoned
-
2022
- 2022-07-13 US US17/863,587 patent/US20230174625A1/en active Pending
Also Published As
Publication number | Publication date |
---|---|
JP5814951B2 (ja) | 2015-11-17 |
US20130005948A1 (en) | 2013-01-03 |
MX2012009892A (es) | 2012-09-12 |
CA2789564A1 (en) | 2011-09-15 |
RU2012141149A (ru) | 2014-04-20 |
JP2015213511A (ja) | 2015-12-03 |
CN102791726A (zh) | 2012-11-21 |
US20200231655A1 (en) | 2020-07-23 |
BR112012020964B1 (pt) | 2021-02-23 |
CN102791726B (zh) | 2016-02-03 |
BR112012020964B8 (pt) | 2021-08-24 |
US20190010216A1 (en) | 2019-01-10 |
MX348739B (es) | 2017-06-27 |
JP5931255B2 (ja) | 2016-06-08 |
EP2545066B1 (en) | 2017-09-20 |
HK1176946A1 (zh) | 2013-08-09 |
RU2558367C2 (ru) | 2015-08-10 |
US9884904B2 (en) | 2018-02-06 |
EP2545066A1 (en) | 2013-01-16 |
ES2648264T3 (es) | 2017-12-29 |
KR20120107140A (ko) | 2012-09-28 |
CA2789564C (en) | 2019-08-13 |
JP2013521323A (ja) | 2013-06-10 |
US20230174625A1 (en) | 2023-06-08 |
KR101555740B1 (ko) | 2015-09-25 |
WO2011110598A1 (en) | 2011-09-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112012020964A2 (pt) | método de produção de imunoglobulina | |
BR112012015988A2 (pt) | método | |
CO6930312A2 (es) | Método de notificación de aplicación | |
CU24158B1 (es) | Método de obtención de 1-kestosa | |
BR112012004707A2 (pt) | método | |
BR112012000624A2 (pt) | método | |
BR112014007958A2 (pt) | método | |
BR112014011900A2 (pt) | um método de purificação de anticorpo | |
FI20090389A0 (fi) | Menetelmä | |
BR112015013188A2 (pt) | método de fermentação otimizado | |
CR20130228A (es) | Anticuerpos neutralizadores anti-ccl20 | |
BR112014001237A2 (pt) | método | |
BR112013015810A2 (pt) | método de fabricação de embalagens. | |
BR112014001765A2 (pt) | método | |
DK2564397T3 (da) | Isotop-produktionsfremgangsmåde | |
BR112014011913A2 (pt) | método de perfuração | |
BR112013009843A2 (pt) | produção de biodestilado renovável | |
BRPI1012526A2 (pt) | método | |
BR112014009795A2 (pt) | método | |
DK2555844T3 (da) | Separationsproces | |
BRPI1010705A2 (pt) | método | |
BR112013009567A2 (pt) | método de produção de hidrocarbonetos | |
BR112013011848A2 (pt) | método de conexão melhorado | |
BR112014011011A2 (pt) | seções de estrutura de poços | |
BR112013009024A2 (pt) | método |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/03/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
B09W | Correction of the decision to grant [chapter 9.1.4 patent gazette] |
Free format text: RETIFICA-SE O DEFERIMENTO NOTIFICADO NA RPI 2607 DE 22/12/2020. |
|
B09W | Correction of the decision to grant [chapter 9.1.4 patent gazette] |
Free format text: RETIFICA-SE O DEFERIMENTO NOTIFICADO NA RPI NO 2607 DE 22/12/2020. |
|
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: REF. RPI 2616 DE 23/02/2021 QUANTO AO RELATORIO DESCRITIVO E AO QUADRO REIVINDICATORIO. |