BR112012020964A2 - método de produção de imunoglobulina - Google Patents

método de produção de imunoglobulina

Info

Publication number
BR112012020964A2
BR112012020964A2 BR112012020964A BR112012020964A BR112012020964A2 BR 112012020964 A2 BR112012020964 A2 BR 112012020964A2 BR 112012020964 A BR112012020964 A BR 112012020964A BR 112012020964 A BR112012020964 A BR 112012020964A BR 112012020964 A2 BR112012020964 A2 BR 112012020964A2
Authority
BR
Brazil
Prior art keywords
production method
immunoglobulin production
immunoglobulin
production
Prior art date
Application number
BR112012020964A
Other languages
English (en)
Other versions
BR112012020964B1 (pt
BR112012020964B8 (pt
Inventor
Cristian Hakemeyer
Felizitas Schwarz
Vinzenz Binder
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42236585&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112012020964(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR112012020964A2 publication Critical patent/BR112012020964A2/pt
Publication of BR112012020964B1 publication Critical patent/BR112012020964B1/pt
Publication of BR112012020964B8 publication Critical patent/BR112012020964B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR112012020964A 2010-03-10 2011-03-09 método para produzir uma imunoglobulina da subclasse igg1 ou igg4 BR112012020964B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10156103 2010-03-10
PCT/EP2011/053547 WO2011110598A1 (en) 2010-03-10 2011-03-09 Method for purifying immunoglobulin solutions

Publications (3)

Publication Number Publication Date
BR112012020964A2 true BR112012020964A2 (pt) 2016-05-03
BR112012020964B1 BR112012020964B1 (pt) 2021-02-23
BR112012020964B8 BR112012020964B8 (pt) 2021-08-24

Family

ID=42236585

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012020964A BR112012020964B8 (pt) 2010-03-10 2011-03-09 método para produzir uma imunoglobulina da subclasse igg1 ou igg4

Country Status (12)

Country Link
US (4) US9884904B2 (pt)
EP (1) EP2545066B1 (pt)
JP (2) JP5814951B2 (pt)
KR (1) KR101555740B1 (pt)
CN (1) CN102791726B (pt)
BR (1) BR112012020964B8 (pt)
CA (1) CA2789564C (pt)
ES (1) ES2648264T3 (pt)
HK (1) HK1176946A1 (pt)
MX (1) MX348739B (pt)
RU (1) RU2558367C2 (pt)
WO (1) WO2011110598A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9884904B2 (en) * 2010-03-10 2018-02-06 Hoffmann-La Roche Inc. Method for purifying polypeptide solutions
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
SG10201605397PA (en) 2011-07-01 2016-08-30 Hoffmann La Roche Method For Separation Of Monomeric Polypeptides From Aggregated Polypeptides
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US20140010820A1 (en) * 2012-05-21 2014-01-09 Abbvie, Inc. Novel purification of non-human antibodies using protein a affinity chromatography
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
US9206390B2 (en) 2012-09-02 2015-12-08 Abbvie, Inc. Methods to control protein heterogeneity
WO2014143205A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2015051293A2 (en) 2013-10-04 2015-04-09 Abbvie, Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
EP3118210B1 (en) 2014-03-11 2019-11-13 Green Cross Holdings Corporation Method for purifying immunoglobulin
CN107108720A (zh) 2014-11-06 2017-08-29 豪夫迈·罗氏有限公司 具有改变的FCRN结合的Fc区变体及其使用方法
CN111378030A (zh) * 2018-12-29 2020-07-07 中国科学院青岛生物能源与过程研究所 一种纳米抗体分离纯化的方法
EP4054629A2 (en) * 2019-11-07 2022-09-14 Janssen Vaccines & Prevention B.V. Protein purification

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196323A (en) 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
IL118069A (en) * 1995-05-02 2000-06-01 Japan Tobacco Inc Monoclonal antibody reactive to human CETP and assay method for human CETP
DE10037781A1 (de) * 2000-08-03 2002-02-21 Agfa Gevaert Ag Vorrichtung und Verfahren zum Beschreiben von Aufzeichnungsmaterial mit Bildinformationen
ES2184594B1 (es) * 2001-01-17 2004-01-01 Probitas Pharma Sa Procedimiento para la produccion de gammaglobulina g humana inactivada de virus.
EP2336149A1 (en) 2001-03-09 2011-06-22 Chugai Seiyaku Kabushiki Kaisha Protein purification method
HUE027134T2 (en) * 2002-09-11 2016-10-28 Chugai Pharmaceutical Co Ltd Method for protein purification
ZA200504990B (en) * 2003-01-09 2006-08-30 Genentech Inc Purification of polypeptides
PT1737891E (pt) 2004-04-13 2013-04-16 Hoffmann La Roche Anticorpos anti p-selectina
ES2565481T3 (es) 2005-03-24 2016-04-05 Thrombogenics N.V. Anticuerpo anti-PlGF novedoso
TWI391399B (zh) 2005-05-25 2013-04-01 Hoffmann La Roche 測定溶離多肽之鹽濃度之方法
EP1896504B1 (en) * 2005-06-17 2012-11-21 Wyeth LLC Methods of purifying fc region containing antibodies
AR062223A1 (es) 2006-08-09 2008-10-22 Glycart Biotechnology Ag Moleculas de adhesion al antigeno que se adhieren a egfr, vectores que los codifican, y sus usos de estas
US9109015B2 (en) 2006-11-01 2015-08-18 Biogen Ma Inc Method of isolating biomacromolecules using low pH and divalent cations
BRPI0812288A2 (pt) 2007-06-01 2014-11-25 Hoffmann La Roche Purificação de imunoglobulina.
GB0818228D0 (en) 2008-10-06 2008-11-12 Avecia Biolog Ltd Purification process
AU2010335282B2 (en) 2009-12-22 2015-05-21 Roche Glycart Ag Anti-HER3 antibodies and uses thereof
US9884904B2 (en) * 2010-03-10 2018-02-06 Hoffmann-La Roche Inc. Method for purifying polypeptide solutions
SG10201605397PA (en) 2011-07-01 2016-08-30 Hoffmann La Roche Method For Separation Of Monomeric Polypeptides From Aggregated Polypeptides

Also Published As

Publication number Publication date
JP5814951B2 (ja) 2015-11-17
US20130005948A1 (en) 2013-01-03
MX2012009892A (es) 2012-09-12
CA2789564A1 (en) 2011-09-15
RU2012141149A (ru) 2014-04-20
JP2015213511A (ja) 2015-12-03
CN102791726A (zh) 2012-11-21
US20200231655A1 (en) 2020-07-23
BR112012020964B1 (pt) 2021-02-23
CN102791726B (zh) 2016-02-03
BR112012020964B8 (pt) 2021-08-24
US20190010216A1 (en) 2019-01-10
MX348739B (es) 2017-06-27
JP5931255B2 (ja) 2016-06-08
EP2545066B1 (en) 2017-09-20
HK1176946A1 (zh) 2013-08-09
RU2558367C2 (ru) 2015-08-10
US9884904B2 (en) 2018-02-06
EP2545066A1 (en) 2013-01-16
ES2648264T3 (es) 2017-12-29
KR20120107140A (ko) 2012-09-28
CA2789564C (en) 2019-08-13
JP2013521323A (ja) 2013-06-10
US20230174625A1 (en) 2023-06-08
KR101555740B1 (ko) 2015-09-25
WO2011110598A1 (en) 2011-09-15

Similar Documents

Publication Publication Date Title
BR112012020964A2 (pt) método de produção de imunoglobulina
BR112012015988A2 (pt) método
CO6930312A2 (es) Método de notificación de aplicación
CU24158B1 (es) Método de obtención de 1-kestosa
BR112012004707A2 (pt) método
BR112012000624A2 (pt) método
BR112014007958A2 (pt) método
BR112014011900A2 (pt) um método de purificação de anticorpo
FI20090389A0 (fi) Menetelmä
BR112015013188A2 (pt) método de fermentação otimizado
CR20130228A (es) Anticuerpos neutralizadores anti-ccl20
BR112014001237A2 (pt) método
BR112013015810A2 (pt) método de fabricação de embalagens.
BR112014001765A2 (pt) método
DK2564397T3 (da) Isotop-produktionsfremgangsmåde
BR112014011913A2 (pt) método de perfuração
BR112013009843A2 (pt) produção de biodestilado renovável
BRPI1012526A2 (pt) método
BR112014009795A2 (pt) método
DK2555844T3 (da) Separationsproces
BRPI1010705A2 (pt) método
BR112013009567A2 (pt) método de produção de hidrocarbonetos
BR112013011848A2 (pt) método de conexão melhorado
BR112014011011A2 (pt) seções de estrutura de poços
BR112013009024A2 (pt) método

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 09/03/2011, OBSERVADAS AS CONDICOES LEGAIS.

B09W Correction of the decision to grant [chapter 9.1.4 patent gazette]

Free format text: RETIFICA-SE O DEFERIMENTO NOTIFICADO NA RPI 2607 DE 22/12/2020.

B09W Correction of the decision to grant [chapter 9.1.4 patent gazette]

Free format text: RETIFICA-SE O DEFERIMENTO NOTIFICADO NA RPI NO 2607 DE 22/12/2020.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REF. RPI 2616 DE 23/02/2021 QUANTO AO RELATORIO DESCRITIVO E AO QUADRO REIVINDICATORIO.