ES2967942T3 - Generación de células beta funcionales a partir de progenitoras endocrinas derivadas de células madre pluripotentes humanas - Google Patents
Generación de células beta funcionales a partir de progenitoras endocrinas derivadas de células madre pluripotentes humanas Download PDFInfo
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- ES2967942T3 ES2967942T3 ES17709385T ES17709385T ES2967942T3 ES 2967942 T3 ES2967942 T3 ES 2967942T3 ES 17709385 T ES17709385 T ES 17709385T ES 17709385 T ES17709385 T ES 17709385T ES 2967942 T3 ES2967942 T3 ES 2967942T3
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| AU2010333839C1 (en) | 2009-12-23 | 2016-07-21 | Janssen Biotech Inc. | Differentiation of human embryonic stem cells |
| KR101986176B1 (ko) | 2010-05-12 | 2019-06-05 | 얀센 바이오테크 인코포레이티드 | 인간 배아 줄기 세포의 분화 |
| JP6312591B2 (ja) | 2011-06-21 | 2018-04-18 | ノヴォ ノルディスク アー／エス | 多能性幹細胞からの胚体内胚葉の効率的な誘導 |
| CN104411815B (zh) | 2012-04-30 | 2017-11-28 | 大学健康网络 | 用于从hPSC生成胰腺祖细胞和功能性β细胞的方法和组合物 |
| JP6470687B2 (ja) | 2012-09-03 | 2019-02-13 | ノヴォ ノルディスク アー／エス | 小分子を用いた多能性幹細胞からの膵臓内胚葉の作製 |
| WO2014048788A1 (en) | 2012-09-27 | 2014-04-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for producing a population of pancreatic beta-cells |
| RU2684215C2 (ru) | 2012-12-31 | 2019-04-04 | Янссен Байотек, Инк. | Способ получения панкреатических эндокринных клеток (варианты) и способ увеличения выхода бета-клеток |
| WO2014127219A1 (en) | 2013-02-14 | 2014-08-21 | The Cleveland Clinic Foundation | Methods for induction of cell fates from pluripotent cells |
| US10920192B2 (en) | 2013-04-23 | 2021-02-16 | Yeda Research And Development Co. Ltd. | Isolated naive pluripotent stem cells and methods of generating same |
| US9540613B2 (en) | 2013-04-29 | 2017-01-10 | Wisconsin Alumni Research Foundation | Methods for producing insulin-secreting beta cells from human pluripotent stem cells |
| KR102580225B1 (ko) | 2013-06-11 | 2023-09-20 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | SC-β 세포 및 조성물 그리고 그 생성 방법 |
| WO2015028614A1 (en) * | 2013-08-30 | 2015-03-05 | Novo Nordisk A/S | Generation of endocrine progenitor cells from human pluripotent stem cells using small molecules |
| US20150250824A1 (en) * | 2014-03-07 | 2015-09-10 | The Research Foundation For The State University Of New York | Methods and compositions for expansion of stem cells and other cells |
| JP6588969B2 (ja) | 2014-05-16 | 2019-10-09 | ヤンセン バイオテツク，インコーポレーテツド | 膵内分泌細胞内のｍａｆａ発現を強化するための小分子の使用 |
| US11274280B2 (en) | 2016-02-24 | 2022-03-15 | Novo Nordisk A/S | Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors |
| CA3110932A1 (en) | 2018-08-30 | 2020-03-05 | Novo Nordisk A/S | Generation of functional beta cells from human pluripotent stem cell-derived endocrine progenitors |
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| JP7123802B2 (ja) | 2022-08-23 |
| CN108699515A (zh) | 2018-10-23 |
| EP3420073B1 (en) | 2023-11-08 |
| JP2019510482A (ja) | 2019-04-18 |
| MA45747A (fr) | 2019-01-02 |
| WO2017144695A9 (en) | 2017-10-19 |
| US11274280B2 (en) | 2022-03-15 |
| WO2017144695A1 (en) | 2017-08-31 |
| EP3420073C0 (en) | 2023-11-08 |
| EP3420073A1 (en) | 2019-01-02 |
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