ES2949953T3 - Factores genéticos asociados con el desarrollo de inhibidores en hemofilia A - Google Patents
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- ES2949953T3 ES2949953T3 ES14154482T ES14154482T ES2949953T3 ES 2949953 T3 ES2949953 T3 ES 2949953T3 ES 14154482 T ES14154482 T ES 14154482T ES 14154482 T ES14154482 T ES 14154482T ES 2949953 T3 ES2949953 T3 ES 2949953T3
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- C—CHEMISTRY; METALLURGY
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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| US32660210P | 2010-04-21 | 2010-04-21 |
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| ES2949953T3 true ES2949953T3 (es) | 2023-10-04 |
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| CA2771999A1 (en) | 2009-08-24 | 2011-03-10 | Amunix Operating Inc. | Coagulation factor vii compositions and methods of making and using same |
| US9637789B2 (en) * | 2010-04-21 | 2017-05-02 | Jan Astermark and Erik Berntorp | Genetic factors associated with inhibitor development in hemophilia A |
| WO2013123457A1 (en) | 2012-02-15 | 2013-08-22 | Biogen Idec Ma Inc. | Recombinant factor viii proteins |
| CN111548418A (zh) | 2012-02-15 | 2020-08-18 | 比奥贝拉蒂治疗公司 | 因子viii组合物及其制备和使用方法 |
| US10548953B2 (en) | 2013-08-14 | 2020-02-04 | Bioverativ Therapeutics Inc. | Factor VIII-XTEN fusions and uses thereof |
| EA201691111A1 (ru) | 2014-01-10 | 2017-01-30 | Байоджен Ма Инк. | Химерные белки фактора viii и их применение |
| UA126016C2 (uk) | 2015-08-03 | 2022-08-03 | Біовератів Терапеутікс Інк. | Злитий білок фактора іх |
| KR101774996B1 (ko) * | 2016-06-23 | 2017-09-19 | 주식회사 녹십자지놈 | 혈우병 치료제의 효능 예측 마커 및 이의 용도 |
| KR20190090827A (ko) | 2016-12-02 | 2019-08-02 | 바이오버라티브 테라퓨틱스 인크. | 키메라 응고 인자를 사용해 혈우병성 관절증을 치료하는 방법 |
| KR102914074B1 (ko) | 2018-05-18 | 2026-01-16 | 바이오버라티브 테라퓨틱스 인크. | A형 혈우병의 치료 방법 |
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| US5210015A (en) | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| EP0728218B1 (en) | 1993-11-12 | 2008-01-02 | PHRI Properties, Inc. | Hybridization probes for nucleic acid detection, universal stems, methods and kits |
| JP3439221B2 (ja) | 1995-12-18 | 2003-08-25 | ワシントン ユニヴァーシティ | 蛍光共鳴エネルギー移動を利用する核酸分析方法 |
| WO2008059009A2 (en) | 2006-11-16 | 2008-05-22 | Crucell Holland B.V. | Factor v mutants for hemostasis in hemophilia |
| US9637789B2 (en) * | 2010-04-21 | 2017-05-02 | Jan Astermark and Erik Berntorp | Genetic factors associated with inhibitor development in hemophilia A |
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| JP2013529071A (ja) | 2013-07-18 |
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| EP2730663A2 (en) | 2014-05-14 |
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| CA3050896A1 (en) | 2011-10-27 |
| JP6189904B2 (ja) | 2017-08-30 |
| WO2011131774A1 (en) | 2011-10-27 |
| JP6568162B2 (ja) | 2019-08-28 |
| CA2796561C (en) | 2019-09-17 |
| US20180016635A1 (en) | 2018-01-18 |
| EP2730663B1 (en) | 2023-03-22 |
| US20120065077A1 (en) | 2012-03-15 |
| CA3050896C (en) | 2023-01-24 |
| EP2561090A1 (en) | 2013-02-27 |
| JP2015226551A (ja) | 2015-12-17 |
| JP6058529B2 (ja) | 2017-01-11 |
| CA2796561A1 (en) | 2011-10-27 |
| AU2011244228A1 (en) | 2012-11-08 |
| US9637789B2 (en) | 2017-05-02 |
| JP2017200491A (ja) | 2017-11-09 |
| EP2730663A3 (en) | 2014-09-10 |
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