ES2914782T3 - Tratamiento para la enfermedad de Parkinson - Google Patents
Tratamiento para la enfermedad de Parkinson Download PDFInfo
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- ES2914782T3 ES2914782T3 ES17743097T ES17743097T ES2914782T3 ES 2914782 T3 ES2914782 T3 ES 2914782T3 ES 17743097 T ES17743097 T ES 17743097T ES 17743097 T ES17743097 T ES 17743097T ES 2914782 T3 ES2914782 T3 ES 2914782T3
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- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000013641 positive control Substances 0.000 description 1
- 229940068988 potassium aspartate Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000036278 prepulse Effects 0.000 description 1
- 230000000750 progressive effect Effects 0.000 description 1
- 239000013558 reference substance Substances 0.000 description 1
- 230000002336 repolarization Effects 0.000 description 1
- 238000003345 scintillation counting Methods 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 210000003523 substantia nigra Anatomy 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000000946 synaptic effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960000351 terfenadine Drugs 0.000 description 1
- 231100001274 therapeutic index Toxicity 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 208000021331 vascular occlusion disease Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201621019087 | 2016-06-02 | ||
| IN201621019185 | 2016-06-02 | ||
| PCT/IN2017/050224 WO2017208267A1 (en) | 2016-06-02 | 2017-06-02 | Treatment for parkinson's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2914782T3 true ES2914782T3 (es) | 2022-06-16 |
Family
ID=59388123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES17743097T Active ES2914782T3 (es) | 2016-06-02 | 2017-06-02 | Tratamiento para la enfermedad de Parkinson |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US10849887B2 (Direct) |
| EP (2) | EP4085912A1 (Direct) |
| JP (1) | JP6974357B2 (Direct) |
| KR (1) | KR102508288B1 (Direct) |
| CN (1) | CN109475539B (Direct) |
| AU (1) | AU2017273415B2 (Direct) |
| CL (1) | CL2018003431A1 (Direct) |
| CY (1) | CY1125285T1 (Direct) |
| DK (1) | DK3463351T3 (Direct) |
| ES (1) | ES2914782T3 (Direct) |
| HR (1) | HRP20220683T1 (Direct) |
| HU (1) | HUE059387T2 (Direct) |
| IL (1) | IL263188B (Direct) |
| LT (1) | LT3463351T (Direct) |
| MX (1) | MX385276B (Direct) |
| MY (1) | MY193754A (Direct) |
| NZ (1) | NZ748592A (Direct) |
| PH (1) | PH12018502457B1 (Direct) |
| PL (1) | PL3463351T3 (Direct) |
| PT (1) | PT3463351T (Direct) |
| RS (1) | RS63243B1 (Direct) |
| SG (1) | SG11201810294QA (Direct) |
| SI (1) | SI3463351T1 (Direct) |
| SM (1) | SMT202200228T1 (Direct) |
| UA (1) | UA123018C2 (Direct) |
| WO (1) | WO2017208267A1 (Direct) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2911040C (en) | 2012-05-02 | 2021-11-16 | Georgetown University | Treating an .alpha.-synucleinopathy with tyrosine kinase inhibitors |
| EP4085912A1 (en) | 2016-06-02 | 2022-11-09 | Sun Pharma Advanced Research Company Limited | Treatment for parkinson s disease |
| CN110606840A (zh) | 2018-06-15 | 2019-12-24 | 日产化学株式会社 | 5-炔基吡啶化合物的制造方法 |
| WO2020106825A1 (en) | 2018-11-20 | 2020-05-28 | Georgetown University | Compositions and methods for treating neurodegenerative, myodegenerative, and lysosomal storage disorders |
| EA202193211A1 (ru) * | 2019-06-11 | 2022-03-30 | Сан Фарма Эдванст Рисерч Компани Лтд. | Лечение синуклеопатий |
| WO2021030783A1 (en) * | 2019-08-15 | 2021-02-18 | Duke University | Compositions and methods for the treatment cancer and cns disorders |
| WO2022024072A1 (en) | 2020-07-31 | 2022-02-03 | Sun Pharma Advanced Research Company Limited | N'-(2-chloro-6-methylbenzoyl)-4-methyl-3-[2-(3-quinolyl) ethynyl]-benzohydrazide for treatment of alzheimer's disease |
| CA3251516A1 (en) | 2022-05-02 | 2023-11-09 | Sun Pharma Advanced Research Company Limited | Methods of reducing progression of neurodegenerative disease |
| KR20250040552A (ko) | 2023-09-14 | 2025-03-24 | 주식회사 엑소스템텍 | 퇴행성 뇌질환 치료 단백질을 포함하는 엑소좀을 이용한 뇌 특이적 퇴행성 뇌질환 치료 단백질 전달 기술 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2608829T3 (es) * | 2011-01-21 | 2017-04-17 | Sun Pharma Advanced Research Company Limited | Inhibidores de tirosina quinasa que contienen diarilacetileno hidrazida |
| CA2911040C (en) | 2012-05-02 | 2021-11-16 | Georgetown University | Treating an .alpha.-synucleinopathy with tyrosine kinase inhibitors |
| CA2985161A1 (en) * | 2015-05-18 | 2016-11-24 | Sun Pharma Advanced Research Company Limited | Novel amidoheteroaryl aroyl hydrazide ethynes |
| EP4085912A1 (en) * | 2016-06-02 | 2022-11-09 | Sun Pharma Advanced Research Company Limited | Treatment for parkinson s disease |
-
2017
- 2017-06-02 EP EP22169420.1A patent/EP4085912A1/en active Pending
- 2017-06-02 UA UAA201812407A patent/UA123018C2/uk unknown
- 2017-06-02 SM SM20220228T patent/SMT202200228T1/it unknown
- 2017-06-02 WO PCT/IN2017/050224 patent/WO2017208267A1/en not_active Ceased
- 2017-06-02 PL PL17743097T patent/PL3463351T3/pl unknown
- 2017-06-02 RS RS20220497A patent/RS63243B1/sr unknown
- 2017-06-02 HR HRP20220683TT patent/HRP20220683T1/hr unknown
- 2017-06-02 HU HUE17743097A patent/HUE059387T2/hu unknown
- 2017-06-02 DK DK17743097.2T patent/DK3463351T3/da active
- 2017-06-02 PT PT177430972T patent/PT3463351T/pt unknown
- 2017-06-02 JP JP2018563062A patent/JP6974357B2/ja active Active
- 2017-06-02 CN CN201780044265.3A patent/CN109475539B/zh active Active
- 2017-06-02 AU AU2017273415A patent/AU2017273415B2/en not_active Ceased
- 2017-06-02 SI SI201731157T patent/SI3463351T1/sl unknown
- 2017-06-02 EP EP17743097.2A patent/EP3463351B1/en active Active
- 2017-06-02 MX MX2018014944A patent/MX385276B/es unknown
- 2017-06-02 SG SG11201810294QA patent/SG11201810294QA/en unknown
- 2017-06-02 LT LTEPPCT/IN2017/050224T patent/LT3463351T/lt unknown
- 2017-06-02 ES ES17743097T patent/ES2914782T3/es active Active
- 2017-06-02 US US16/304,914 patent/US10849887B2/en active Active
- 2017-06-02 KR KR1020187034626A patent/KR102508288B1/ko active Active
- 2017-06-02 NZ NZ748592A patent/NZ748592A/en unknown
- 2017-06-02 MY MYPI2018002187A patent/MY193754A/en unknown
-
2018
- 2018-11-21 IL IL263188A patent/IL263188B/en unknown
- 2018-11-22 PH PH12018502457A patent/PH12018502457B1/en unknown
- 2018-11-30 CL CL2018003431A patent/CL2018003431A1/es unknown
-
2020
- 2020-10-01 US US17/061,139 patent/US11583522B2/en active Active
-
2022
- 2022-05-18 US US17/747,472 patent/US11813252B2/en active Active
- 2022-05-27 CY CY20221100369T patent/CY1125285T1/el unknown
-
2023
- 2023-10-11 US US18/378,901 patent/US20240066014A1/en not_active Abandoned
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