SG11201810294QA - Treatment for parkinson's disease - Google Patents
Treatment for parkinson's diseaseInfo
- Publication number
- SG11201810294QA SG11201810294QA SG11201810294QA SG11201810294QA SG11201810294QA SG 11201810294Q A SG11201810294Q A SG 11201810294QA SG 11201810294Q A SG11201810294Q A SG 11201810294QA SG 11201810294Q A SG11201810294Q A SG 11201810294QA SG 11201810294Q A SG11201810294Q A SG 11201810294QA
- Authority
- SG
- Singapore
- Prior art keywords
- pharma
- sun
- road
- advanced research
- tandalja
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property 1 MI 11111 0 11101 HOE 010 1111 1 0 01010 HEM OH 100 1111 1111011110111111 Organization International Bureau (10) International Publication Number (43) International Publication Date . . .., . .. WO 2017/208267 Al 07 December 2017 (07.12.2017) WIP0 I PCT (51) International Patent Classification: ited, Sun Pharma Advanced Research Centre, Nima Corn- A61K 31/44 (2006.01) A61P 25/16 (2006.01) pound, Near Pratham Enclave, Tandalja Road, Gujarat, Bar- A61K 31/47 (2006.01) oda 390020 (IN). (21) International Application Number: (81) Designated States (unless otherwise indicated, for every PCT/IN2017/050224 kind of national protection available): AE, AG, AL, AM, (22) International Filing Date: AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, 02 June 2017 (02.06.2017) CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, (25) Filing Language: English HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, (26) Publication Language: English KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, (30) Priority Data: PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, 201621019087 02 June 2016 (02.06.2016) IN SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, 201621019185 02 June 2016 (02.06.2016) IN TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (71) Applicant: SUN PHARMA ADVANCED RESEARCH (84) Designated States (unless otherwise indicated, for every COMPANY LIMITED [IN/IN]; 17/B, Mahal Industrial kind of regional protection available): ARIPO (BW, GH, Estate, Mahakali Caves Road, Andheri (E), Mumbai 400093 GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, (IN). UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, (72) Inventors: DAMLE, Nitin Krishnaji; Sun Pharma Ad- EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, vaned Research Company Limited, Sun Pharma Advanced MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, Research Centre, Nima Compound, Near Pratham Enclave, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, Tandalja Road, Gujarat, Baroda 390020 (IN). MAND-KM, ML, MR, NE, SN, TD, TG). — = HANE, Sanjay Nandlalji; Sun Pharma Advanced Re- _ search Company Limited, Sun Pharma Advanced Research Declarations under Rule 4.17: Centre, Nima Compound, Near Pratham Enclave, Tandalja — as to applicant's entitlement to apply for and be granted a Road, Gujarat, Baroda 390020 (IN). UPADHYA, Manoj patent (Rule 4.17(ii)) Atmaramji; Sun Pharma Advanced Research Company — of inventorship (Rule 4.17(iv)) Limited, Sun Pharma Advanced Research Centre, Nima _ = Compound, Near Pratham Enclave, Tandalja Road, Gu- Published: jarat, Baroda 390020 (IN). MEHETRE, Sameer Vish- — with international search report (Art. 21(3)) — = wanath; Sun Pharma Advanced Research Company Lim- — before the expiration of the time limit for amending the = ited, Sun Pharma Advanced Research Centre, Nima Com- claims and to be republished in the event of receipt of = pound, Near Pratham Enclave, Tandalja Road, Gujarat, Bar- amendments (Rule 48.2(h)) oda 390020 (IN). CHIDREWAR, Gajanan Uttamrao; = = Sun Pharma Advanced Research Company Limited, Sun = Pharma Advanced Research Centre, Nima Compound, Near _ Pratham Enclave, Tandalja Road, Gujarat, Baroda 390020 = (IN). SENGUPTA, Prabal; Sun Pharma Advanced Re- = search Company Limited, Sun Pharma Advanced Research = — Centre, Nima Compound, Near Pratham Enclave, Tandalja = Road, Gujarat, Baroda 390020 (IN). CHITTURI, Trinad- - = ha Rao; Sun Pharma Advanced Research Company Lim- - ,_ 1 (54) Title: TREATMENT FOR PARKINSON'S DISEASE (57) : The invention relates to a method of treating or preventing IN Parkinson's disease in a subject comprising administering a compound of Formula 1 N R3 R4 I wherein, R1 is —NHC(0) C3_6 cycloalkyl and R2 is hydrogen; or R1 and R2 along c3 C R -r\ . % with the carbon atoms to which they are attached form a six membered aromatic C Z el NH 1 „, ring, wherein the ring is substituted with one or more groups selected from hydrogen, 0 NH 'ir . ' , \"' -- halogen and C1_6 alkyl; R3 and R4 are independently selected from group comprising IN o Il hydrogen, halogen, C1_3 alkyl, OCi_3 alkyl, NO2, SC _3 alkyl, C1_3 haloalkyl, 0C1-3 © Formula I haloalkyl, and SC haloalkyl; or a pharmaceutically acceptable salt thereof. 1 _ 3 N C
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN201621019185 | 2016-06-02 | ||
| IN201621019087 | 2016-06-02 | ||
| PCT/IN2017/050224 WO2017208267A1 (en) | 2016-06-02 | 2017-06-02 | Treatment for parkinson's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201810294QA true SG11201810294QA (en) | 2018-12-28 |
Family
ID=59388123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201810294QA SG11201810294QA (en) | 2016-06-02 | 2017-06-02 | Treatment for parkinson's disease |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US10849887B2 (en) |
| EP (2) | EP3463351B1 (en) |
| JP (1) | JP6974357B2 (en) |
| KR (1) | KR102508288B1 (en) |
| CN (1) | CN109475539B (en) |
| AU (1) | AU2017273415B2 (en) |
| BR (1) | BR112018074439A2 (en) |
| CA (1) | CA3024976A1 (en) |
| CL (1) | CL2018003431A1 (en) |
| DK (1) | DK3463351T3 (en) |
| ES (1) | ES2914782T3 (en) |
| HR (1) | HRP20220683T1 (en) |
| HU (1) | HUE059387T2 (en) |
| IL (1) | IL263188B (en) |
| LT (1) | LT3463351T (en) |
| MX (1) | MX2018014944A (en) |
| MY (1) | MY193754A (en) |
| PH (1) | PH12018502457A1 (en) |
| PL (1) | PL3463351T3 (en) |
| PT (1) | PT3463351T (en) |
| RS (1) | RS63243B1 (en) |
| SG (1) | SG11201810294QA (en) |
| SI (1) | SI3463351T1 (en) |
| UA (1) | UA123018C2 (en) |
| WO (1) | WO2017208267A1 (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2943113T3 (en) | 2012-05-02 | 2023-06-09 | Univ Georgetown | Treatment of amyotrophic lateral sclerosis with tyrosine kinase inhibitors |
| ES2914782T3 (en) * | 2016-06-02 | 2022-06-16 | Sun Pharma Advanced Res Co Ltd | Treatment for Parkinson's disease |
| CN110606840A (en) | 2018-06-15 | 2019-12-24 | 日产化学株式会社 | Method for producing 5-alkynylpyridine compound |
| US20220257582A1 (en) | 2019-06-11 | 2022-08-18 | Sun Pharma Advanced Research Company Limited | Treatment for synucleinopathies |
| WO2021030783A1 (en) * | 2019-08-15 | 2021-02-18 | Duke University | Compositions and methods for the treatment cancer and cns disorders |
| JP2023536440A (en) | 2020-07-31 | 2023-08-25 | サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド | N'-(2-chloro-6-methylbenzoyl)-4-methyl-3-[2-(3-quinolyl)ethynyl]-benzohydrazide for the treatment of Alzheimer's disease |
| WO2023214314A1 (en) | 2022-05-02 | 2023-11-09 | Sun Pharma Advanced Research Company Limited | Vodobatinib for reducing progression of parkinson's disease |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2825367C (en) * | 2011-01-21 | 2018-09-25 | Sun Pharma Advanced Research Company Ltd. | Diarylacetylene hydrazide containing tyrosine kinase inhibitors |
| ES2943113T3 (en) | 2012-05-02 | 2023-06-09 | Univ Georgetown | Treatment of amyotrophic lateral sclerosis with tyrosine kinase inhibitors |
| EP3297991B1 (en) * | 2015-05-18 | 2020-01-29 | Sun Pharma Advanced Research Company Ltd | Novel amidoheteroaryl aroyl hydrazide ethynes |
| ES2914782T3 (en) * | 2016-06-02 | 2022-06-16 | Sun Pharma Advanced Res Co Ltd | Treatment for Parkinson's disease |
-
2017
- 2017-06-02 ES ES17743097T patent/ES2914782T3/en active Active
- 2017-06-02 DK DK17743097.2T patent/DK3463351T3/en active
- 2017-06-02 AU AU2017273415A patent/AU2017273415B2/en active Active
- 2017-06-02 PT PT177430972T patent/PT3463351T/en unknown
- 2017-06-02 MX MX2018014944A patent/MX2018014944A/en unknown
- 2017-06-02 PL PL17743097T patent/PL3463351T3/en unknown
- 2017-06-02 UA UAA201812407A patent/UA123018C2/en unknown
- 2017-06-02 WO PCT/IN2017/050224 patent/WO2017208267A1/en unknown
- 2017-06-02 KR KR1020187034626A patent/KR102508288B1/en active IP Right Grant
- 2017-06-02 HU HUE17743097A patent/HUE059387T2/en unknown
- 2017-06-02 EP EP17743097.2A patent/EP3463351B1/en active Active
- 2017-06-02 CA CA3024976A patent/CA3024976A1/en active Pending
- 2017-06-02 LT LTEPPCT/IN2017/050224T patent/LT3463351T/en unknown
- 2017-06-02 SG SG11201810294QA patent/SG11201810294QA/en unknown
- 2017-06-02 SI SI201731157T patent/SI3463351T1/en unknown
- 2017-06-02 US US16/304,914 patent/US10849887B2/en active Active
- 2017-06-02 MY MYPI2018002187A patent/MY193754A/en unknown
- 2017-06-02 CN CN201780044265.3A patent/CN109475539B/en active Active
- 2017-06-02 BR BR112018074439-5A patent/BR112018074439A2/en active Search and Examination
- 2017-06-02 EP EP22169420.1A patent/EP4085912A1/en active Pending
- 2017-06-02 JP JP2018563062A patent/JP6974357B2/en active Active
- 2017-06-02 HR HRP20220683TT patent/HRP20220683T1/en unknown
- 2017-06-02 RS RS20220497A patent/RS63243B1/en unknown
-
2018
- 2018-11-21 IL IL263188A patent/IL263188B/en unknown
- 2018-11-22 PH PH12018502457A patent/PH12018502457A1/en unknown
- 2018-11-30 CL CL2018003431A patent/CL2018003431A1/en unknown
-
2020
- 2020-10-01 US US17/061,139 patent/US11583522B2/en active Active
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2022
- 2022-05-18 US US17/747,472 patent/US11813252B2/en active Active
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2023
- 2023-10-11 US US18/378,901 patent/US20240066014A1/en active Pending
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