ES2912465T3 - Compuestos y métodos para modular la tirosina quinasa de Bruton - Google Patents
Compuestos y métodos para modular la tirosina quinasa de Bruton Download PDFInfo
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- ES2912465T3 ES2912465T3 ES17764260T ES17764260T ES2912465T3 ES 2912465 T3 ES2912465 T3 ES 2912465T3 ES 17764260 T ES17764260 T ES 17764260T ES 17764260 T ES17764260 T ES 17764260T ES 2912465 T3 ES2912465 T3 ES 2912465T3
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Landscapes
- Health & Medical Sciences (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
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| PCT/US2017/021966 WO2017156495A1 (en) | 2016-03-11 | 2017-03-10 | Compounds and methods for modulating bruton's tyrosine kinase |
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| US11554118B2 (en) * | 2017-03-22 | 2023-01-17 | Xibin Liao | Bruton's tyrosine kinase inhibitors |
| KR102384924B1 (ko) * | 2017-07-12 | 2022-04-08 | 주식회사 대웅제약 | 신규한 1h-피라졸로피리딘 유도체 및 이를 포함하는 약학 조성물 |
| CN108191871B (zh) * | 2018-01-02 | 2020-02-18 | 成都倍特药业有限公司 | 新型布鲁顿酪氨酸激酶抑制剂及其制备方法和应用 |
| CN111662232B (zh) * | 2019-03-06 | 2022-08-02 | 中国科学院上海药物研究所 | 具有2h-吲唑结构的小分子化合物及其合成和应用 |
| CN113544130B (zh) * | 2019-05-31 | 2024-01-09 | 西藏海思科制药有限公司 | 一种btk抑制剂环衍生物及其制备方法和药学上的应用 |
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| CA2641254A1 (en) * | 2006-02-14 | 2007-08-23 | Vertex Pharmaceuticals Incorporated | Pyrrolo(3,2-c) pyridines useful as inhibitors of protein kinases |
| PL2526933T3 (pl) | 2006-09-22 | 2015-08-31 | Pharmacyclics Llc | Inhibitory kinazy tyrozynowej Brutona |
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-
2017
- 2017-03-10 PL PL17764260T patent/PL3426637T3/pl unknown
- 2017-03-10 CN CN201780028799.7A patent/CN109071455B/zh active Active
- 2017-03-10 KR KR1020187029381A patent/KR102416971B1/ko active Active
- 2017-03-10 WO PCT/US2017/021966 patent/WO2017156495A1/en not_active Ceased
- 2017-03-10 EP EP17764260.0A patent/EP3426637B1/en active Active
- 2017-03-10 MX MX2018010971A patent/MX388026B/es unknown
- 2017-03-10 US US16/083,409 patent/US10870652B2/en active Active
- 2017-03-10 ES ES17764260T patent/ES2912465T3/es active Active
- 2017-03-10 CN CN202210903642.7A patent/CN115746000A/zh active Pending
- 2017-03-10 AU AU2017230098A patent/AU2017230098B2/en active Active
- 2017-03-10 JP JP2018547964A patent/JP6972002B2/ja active Active
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2018
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- 2018-09-05 ZA ZA2018/05951A patent/ZA201805951B/en unknown
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2020
- 2020-08-27 US US17/004,943 patent/US11306099B1/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN109071455A (zh) | 2018-12-21 |
| US10870652B2 (en) | 2020-12-22 |
| EP3426637B1 (en) | 2022-02-09 |
| CN109071455B (zh) | 2022-08-02 |
| WO2017156495A8 (en) | 2018-09-27 |
| PL3426637T3 (pl) | 2022-05-30 |
| EP3426637A1 (en) | 2019-01-16 |
| EP3426637A4 (en) | 2019-09-18 |
| MX2018010971A (es) | 2019-03-28 |
| KR20180133415A (ko) | 2018-12-14 |
| JP6972002B2 (ja) | 2021-11-24 |
| KR102416971B1 (ko) | 2022-07-04 |
| AU2017230098B2 (en) | 2021-03-25 |
| AU2017230098A1 (en) | 2018-09-20 |
| ZA201805951B (en) | 2020-12-23 |
| IL261583A (en) | 2018-10-31 |
| MX388026B (es) | 2025-03-19 |
| JP2019507793A (ja) | 2019-03-22 |
| NZ745927A (en) | 2024-05-31 |
| WO2017156495A1 (en) | 2017-09-14 |
| CA3017567A1 (en) | 2017-09-14 |
| CN115746000A (zh) | 2023-03-07 |
| US11306099B1 (en) | 2022-04-19 |
| US20190106423A1 (en) | 2019-04-11 |
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