ES2905083T3 - Composiciones líquidas de tioureileno - Google Patents
Composiciones líquidas de tioureileno Download PDFInfo
- Publication number
- ES2905083T3 ES2905083T3 ES15732908T ES15732908T ES2905083T3 ES 2905083 T3 ES2905083 T3 ES 2905083T3 ES 15732908 T ES15732908 T ES 15732908T ES 15732908 T ES15732908 T ES 15732908T ES 2905083 T3 ES2905083 T3 ES 2905083T3
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- ES
- Spain
- Prior art keywords
- composition according
- composition
- liquid
- compositions
- methimazole
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims abstract description 108
- 239000007788 liquid Substances 0.000 title claims abstract description 51
- PMRYVIKBURPHAH-UHFFFAOYSA-N methimazole Chemical compound CN1C=CNC1=S PMRYVIKBURPHAH-UHFFFAOYSA-N 0.000 claims abstract description 27
- 229960002178 thiamazole Drugs 0.000 claims abstract description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 21
- 150000003839 salts Chemical class 0.000 claims abstract description 13
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- 235000010493 xanthan gum Nutrition 0.000 claims abstract description 11
- 239000000230 xanthan gum Substances 0.000 claims abstract description 11
- 229940082509 xanthan gum Drugs 0.000 claims abstract description 11
- 239000000243 solution Substances 0.000 claims description 21
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 15
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- 239000002562 thickening agent Substances 0.000 claims description 11
- 239000000080 wetting agent Substances 0.000 claims description 9
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 7
- 239000003814 drug Substances 0.000 claims description 6
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 6
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- AMTWCFIAVKBGOD-UHFFFAOYSA-N dioxosilane;methoxy-dimethyl-trimethylsilyloxysilane Chemical compound O=[Si]=O.CO[Si](C)(C)O[Si](C)(C)C AMTWCFIAVKBGOD-UHFFFAOYSA-N 0.000 claims description 4
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- KDQPSPMLNJTZAL-UHFFFAOYSA-L disodium hydrogenphosphate dihydrate Chemical compound O.O.[Na+].[Na+].OP([O-])([O-])=O KDQPSPMLNJTZAL-UHFFFAOYSA-L 0.000 claims description 3
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- OOSZCNKVJAVHJI-UHFFFAOYSA-N 1-[(4-fluorophenyl)methyl]piperazine Chemical compound C1=CC(F)=CC=C1CN1CCNCC1 OOSZCNKVJAVHJI-UHFFFAOYSA-N 0.000 claims description 2
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- UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 description 4
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 4
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- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 3
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- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 3
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- 244000215068 Acacia senegal Species 0.000 description 2
- 241000416162 Astragalus gummifer Species 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- XUIIKFGFIJCVMT-GFCCVEGCSA-N D-thyroxine Chemical compound IC1=CC(C[C@@H](N)C(O)=O)=CC(I)=C1OC1=CC(I)=C(O)C(I)=C1 XUIIKFGFIJCVMT-GFCCVEGCSA-N 0.000 description 2
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- OEUVSBXAMBLPES-UHFFFAOYSA-L calcium stearoyl-2-lactylate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC(=O)OC(C)C(=O)OC(C)C([O-])=O.CCCCCCCCCCCCCCCCCC(=O)OC(C)C(=O)OC(C)C([O-])=O OEUVSBXAMBLPES-UHFFFAOYSA-L 0.000 description 2
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Landscapes
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- Nutrition Science (AREA)
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1411310.4A GB2527555B (en) | 2014-06-25 | 2014-06-25 | Stable methimazole liquid compositions |
| PCT/GB2015/051824 WO2015198033A1 (en) | 2014-06-25 | 2015-06-23 | Thioureylene liquid compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2905083T3 true ES2905083T3 (es) | 2022-04-19 |
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| ES15732908T Active ES2905083T3 (es) | 2014-06-25 | 2015-06-23 | Composiciones líquidas de tioureileno |
| ES18197341T Active ES2884573T3 (es) | 2014-06-25 | 2015-06-23 | Composiciones líquidas de tioureilenos |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES18197341T Active ES2884573T3 (es) | 2014-06-25 | 2015-06-23 | Composiciones líquidas de tioureilenos |
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| US (6) | US10045967B2 (https=) |
| EP (2) | EP3160441B1 (https=) |
| JP (1) | JP6799465B2 (https=) |
| AU (1) | AU2015278962B2 (https=) |
| CA (1) | CA2952336C (https=) |
| CY (2) | CY1124535T1 (https=) |
| DK (2) | DK3160441T3 (https=) |
| ES (2) | ES2905083T3 (https=) |
| GB (1) | GB2527555B (https=) |
| HR (2) | HRP20220078T1 (https=) |
| HU (1) | HUE056787T2 (https=) |
| LT (2) | LT3160441T (https=) |
| NZ (1) | NZ728018A (https=) |
| PL (2) | PL3441063T3 (https=) |
| PT (2) | PT3160441T (https=) |
| RS (2) | RS62321B1 (https=) |
| SI (2) | SI3441063T1 (https=) |
| SM (2) | SMT202200043T1 (https=) |
| WO (1) | WO2015198033A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2527555B (en) | 2014-06-25 | 2018-09-19 | Norbrook Lab Ltd | Stable methimazole liquid compositions |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4096174A (en) * | 1977-07-01 | 1978-06-20 | American Cyanamid Company | Anionic naphthalene thioureido-diphenyloxides |
| DE3013839A1 (de) * | 1979-04-13 | 1980-10-30 | Freunt Ind Co Ltd | Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung |
| US5310742A (en) * | 1992-11-30 | 1994-05-10 | Elias Alan N | Uses for thioureylenes |
| CA2407335C (en) * | 2000-05-03 | 2010-08-03 | Joe D'silva | Process and device for producing liquid dosage formulations |
| US20050158367A1 (en) * | 2004-01-16 | 2005-07-21 | The Procter & Gamble Company | Liquid compositions comprising one or more medicaments |
| AU2007207991B2 (en) * | 2006-01-26 | 2011-08-04 | Hill's Pet Nutrition, Inc. | Methods and compositions for treating feline hyperthyroidism |
| GB2438287A (en) * | 2006-05-19 | 2007-11-21 | Norbrook Lab Ltd | Stable aqueous suspension |
| US20100286154A1 (en) * | 2007-11-15 | 2010-11-11 | Susanne Christine Wieland-Berghausen | Antihelmintic paste |
| GB2527555B (en) | 2014-06-25 | 2018-09-19 | Norbrook Lab Ltd | Stable methimazole liquid compositions |
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2014
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2015
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- 2015-06-23 PL PL18197341T patent/PL3441063T3/pl unknown
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- 2015-06-23 CA CA2952336A patent/CA2952336C/en active Active
- 2015-06-23 DK DK15732908.7T patent/DK3160441T3/da active
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- 2015-06-23 DK DK18197341.3T patent/DK3441063T3/da active
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- 2015-06-23 JP JP2016575086A patent/JP6799465B2/ja active Active
- 2015-06-23 PT PT181973413T patent/PT3441063T/pt unknown
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- 2015-06-23 LT LTEP18197341.3T patent/LT3441063T/lt unknown
- 2015-06-23 HU HUE18197341A patent/HUE056787T2/hu unknown
- 2015-06-23 WO PCT/GB2015/051824 patent/WO2015198033A1/en not_active Ceased
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2018
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2020
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2022
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2023
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