JP6799465B2 - チオウレイレン液体組成物 - Google Patents

チオウレイレン液体組成物 Download PDF

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JP6799465B2
JP6799465B2 JP2016575086A JP2016575086A JP6799465B2 JP 6799465 B2 JP6799465 B2 JP 6799465B2 JP 2016575086 A JP2016575086 A JP 2016575086A JP 2016575086 A JP2016575086 A JP 2016575086A JP 6799465 B2 JP6799465 B2 JP 6799465B2
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composition according
composition
xanthan gum
present
thioureylene
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Japanese (ja)
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JP2017519029A (ja
JP2017519029A5 (https=
Inventor
レイノルズ，ルイーズ
アムレティア，マニッシュ
Original Assignee
ノルブルック ラボラトリーズ リミテッド
ノルブルック ラボラトリーズ リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016575086A 2014-06-25 2015-06-23 チオウレイレン液体組成物 Active JP6799465B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1411310.4 2014-06-25
GB1411310.4A GB2527555B (en) 2014-06-25 2014-06-25 Stable methimazole liquid compositions
PCT/GB2015/051824 WO2015198033A1 (en) 2014-06-25 2015-06-23 Thioureylene liquid compositions

Publications (3)

Publication Number Publication Date
JP2017519029A JP2017519029A (ja) 2017-07-13
JP2017519029A5 JP2017519029A5 (https=) 2018-07-19
JP6799465B2 true JP6799465B2 (ja) 2020-12-16

Family

ID=51410113

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2016575086A Active JP6799465B2 (ja) 2014-06-25 2015-06-23 チオウレイレン液体組成物

Country Status (19)

Country Link
US (6) US10045967B2 (https=)
EP (2) EP3160441B1 (https=)
JP (1) JP6799465B2 (https=)
AU (1) AU2015278962B2 (https=)
CA (1) CA2952336C (https=)
CY (2) CY1124535T1 (https=)
DK (2) DK3160441T3 (https=)
ES (2) ES2905083T3 (https=)
GB (1) GB2527555B (https=)
HR (2) HRP20220078T1 (https=)
HU (1) HUE056787T2 (https=)
LT (2) LT3160441T (https=)
NZ (1) NZ728018A (https=)
PL (2) PL3441063T3 (https=)
PT (2) PT3160441T (https=)
RS (2) RS62321B1 (https=)
SI (2) SI3441063T1 (https=)
SM (2) SMT202200043T1 (https=)
WO (1) WO2015198033A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2527555B (en) 2014-06-25 2018-09-19 Norbrook Lab Ltd Stable methimazole liquid compositions

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096174A (en) * 1977-07-01 1978-06-20 American Cyanamid Company Anionic naphthalene thioureido-diphenyloxides
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
US5310742A (en) * 1992-11-30 1994-05-10 Elias Alan N Uses for thioureylenes
CA2407335C (en) * 2000-05-03 2010-08-03 Joe D'silva Process and device for producing liquid dosage formulations
US20050158367A1 (en) * 2004-01-16 2005-07-21 The Procter & Gamble Company Liquid compositions comprising one or more medicaments
AU2007207991B2 (en) * 2006-01-26 2011-08-04 Hill's Pet Nutrition, Inc. Methods and compositions for treating feline hyperthyroidism
GB2438287A (en) * 2006-05-19 2007-11-21 Norbrook Lab Ltd Stable aqueous suspension
US20100286154A1 (en) * 2007-11-15 2010-11-11 Susanne Christine Wieland-Berghausen Antihelmintic paste
GB2527555B (en) 2014-06-25 2018-09-19 Norbrook Lab Ltd Stable methimazole liquid compositions

Also Published As

Publication number Publication date
WO2015198033A1 (en) 2015-12-30
RS62850B1 (sr) 2022-02-28
LT3160441T (lt) 2022-02-25
CY1124961T1 (el) 2023-01-05
PL3160441T3 (pl) 2022-02-28
NZ728018A (en) 2019-06-28
ES2884573T3 (es) 2021-12-10
GB201411310D0 (en) 2014-08-06
JP2017519029A (ja) 2017-07-13
HRP20211354T1 (hr) 2021-11-26
US20180318262A1 (en) 2018-11-08
US20200405690A1 (en) 2020-12-31
SMT202200043T1 (it) 2022-03-21
EP3441063A1 (en) 2019-02-13
ES2905083T3 (es) 2022-04-19
HRP20220078T1 (hr) 2022-04-15
HRP20211354T8 (hr) 2022-03-04
US20210361623A1 (en) 2021-11-25
US12171749B2 (en) 2024-12-24
EP3441063B1 (en) 2021-07-21
US10045967B2 (en) 2018-08-14
GB2527555B (en) 2018-09-19
DK3441063T3 (da) 2021-08-30
SMT202100487T1 (it) 2021-09-14
SI3160441T1 (sl) 2022-04-29
SI3441063T1 (sl) 2021-12-31
CA2952336C (en) 2023-02-14
RS62321B1 (sr) 2021-10-29
EP3160441B1 (en) 2022-01-12
US20250064785A1 (en) 2025-02-27
LT3441063T (lt) 2021-10-11
US20170135987A1 (en) 2017-05-18
PL3441063T3 (pl) 2021-12-27
GB2527555A (en) 2015-12-30
CA2952336A1 (en) 2015-12-30
AU2015278962B2 (en) 2019-07-04
HUE056787T2 (hu) 2022-03-28
AU2015278962A1 (en) 2016-12-22
PT3160441T (pt) 2022-01-28
US11123327B2 (en) 2021-09-21
EP3160441A1 (en) 2017-05-03
US20230404978A1 (en) 2023-12-21
CY1124535T1 (el) 2022-07-22
PT3441063T (pt) 2021-08-31
US11738005B2 (en) 2023-08-29
DK3160441T3 (da) 2022-01-31

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