ES2897933T3 - Proteínas de Mycobacterium tuberculosis - Google Patents

Proteínas de Mycobacterium tuberculosis Download PDF

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Publication number
ES2897933T3
ES2897933T3 ES15753982T ES15753982T ES2897933T3 ES 2897933 T3 ES2897933 T3 ES 2897933T3 ES 15753982 T ES15753982 T ES 15753982T ES 15753982 T ES15753982 T ES 15753982T ES 2897933 T3 ES2897933 T3 ES 2897933T3
Authority
ES
Spain
Prior art keywords
fragments
seq
tuberculosis
protein
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15753982T
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English (en)
Spanish (es)
Inventor
Massimo Amicosante
Ian Durrant
Scott Tasker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oxford Immunotec Ltd
Original Assignee
Oxford Immunotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Immunotec Ltd filed Critical Oxford Immunotec Ltd
Application granted granted Critical
Publication of ES2897933T3 publication Critical patent/ES2897933T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/5695Mycobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • A61P31/06Antibacterial agents for tuberculosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6866Interferon
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/555Interferons [IFN]
    • G01N2333/57IFN-gamma
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70514CD4
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/70517CD8
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
ES15753982T 2014-08-15 2015-08-14 Proteínas de Mycobacterium tuberculosis Active ES2897933T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BG11180414 2014-08-15
BG11204515 2015-06-30
PCT/GB2015/052362 WO2016024129A1 (en) 2014-08-15 2015-08-14 Mycobacterium tuberculosis proteins

Publications (1)

Publication Number Publication Date
ES2897933T3 true ES2897933T3 (es) 2022-03-03

Family

ID=53969374

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15753982T Active ES2897933T3 (es) 2014-08-15 2015-08-14 Proteínas de Mycobacterium tuberculosis

Country Status (6)

Country Link
US (1) US10295538B2 (enExample)
EP (1) EP3180353B1 (enExample)
JP (2) JP6781698B2 (enExample)
CN (1) CN107110862B (enExample)
ES (1) ES2897933T3 (enExample)
WO (1) WO2016024129A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106442983B (zh) * 2016-08-31 2018-07-03 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌抗原蛋白Rv3793及其T细胞表位肽的应用
CN106248936B (zh) * 2016-08-31 2018-09-25 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌抗原蛋白Rv2201及其T细胞表位肽的应用
CN112020555B (zh) * 2018-05-02 2024-06-21 国立大学法人新潟大学 肽及其应用
CN116348767A (zh) 2020-10-06 2023-06-27 西菲伊德公司 诊断结核病以及区分活动性和潜伏性结核病的方法
GB202101078D0 (en) * 2021-01-27 2021-03-10 Oxford Immunotec Ltd Fragment pools
CN114736276B (zh) * 2022-05-24 2023-08-01 中国人民解放军总医院第八医学中心 结核分枝杆菌ltbi-rd相关蛋白抗原的ctl表位肽及其应用
CN115957312A (zh) * 2023-01-17 2023-04-14 武汉大学 B4galt1在制备抗结核分枝杆菌感染的药物中的应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002314358C1 (en) * 2001-07-04 2009-03-26 The Secretary Of State For Health Mycobacterial antigens expressed during latency
WO2004099771A1 (en) * 2003-05-08 2004-11-18 Statens Serum Institut A new specific epitope based immunological diagnosis of tuberculosis
ITRM20040091A1 (it) * 2004-02-19 2004-05-19 Istituto Naz Per Le Malattie Test immunologico rapido per la diagnosi ed il monitoraggio dell'infezione tubercolare.
GB0406271D0 (en) 2004-03-19 2004-04-21 Isis Innovation Diagnostic test
WO2006000045A1 (en) * 2004-06-25 2006-01-05 Proteome Systems Intellectual Property Pty Ltd Novel methods of diagnosis and treatment of m. tuberculosis infection and reagents therefor i
WO2007131293A1 (en) * 2006-05-16 2007-11-22 Proteome Systems Limited Methods of diagnosis and treatment of m. tuberculosis infection and reagents therefor vi
US7776341B2 (en) 2006-08-10 2010-08-17 Colorado State University Research Foundation Biomarkers of tuberculosis that distinguish disease categories: use as serodiagnostic antigens
SI2315834T1 (sl) * 2008-07-25 2018-09-28 Glaxosmithkline Biologicals S.A. Tuberkulozni Rv2386c protein, sestavki in njegove uporabe
WO2010132054A1 (en) * 2009-05-13 2010-11-18 Immport Therapeutics, Inc. Compositions and methods for immunodominant antigens of mycobacterium tuberculosis
CN103884847B (zh) 2014-03-14 2015-08-26 中国科学院生物物理研究所 一种结核分枝杆菌全蛋白质芯片及应用

Also Published As

Publication number Publication date
JP2020198886A (ja) 2020-12-17
EP3180353B1 (en) 2021-09-22
WO2016024129A1 (en) 2016-02-18
JP2017526742A (ja) 2017-09-14
US10295538B2 (en) 2019-05-21
JP6781698B2 (ja) 2020-11-04
US20170234871A1 (en) 2017-08-17
CN107110862A (zh) 2017-08-29
CN107110862B (zh) 2021-03-16
EP3180353A1 (en) 2017-06-21

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