ES2875875T3 - Pegamento de fibrina de un componente que comprende zimógenos - Google Patents
Pegamento de fibrina de un componente que comprende zimógenos Download PDFInfo
- Publication number
- ES2875875T3 ES2875875T3 ES14830890T ES14830890T ES2875875T3 ES 2875875 T3 ES2875875 T3 ES 2875875T3 ES 14830890 T ES14830890 T ES 14830890T ES 14830890 T ES14830890 T ES 14830890T ES 2875875 T3 ES2875875 T3 ES 2875875T3
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- Prior art keywords
- formulation
- factor
- vitamin
- fibrinogen
- zymogens
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21006—Coagulation factor Xa (3.4.21.6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
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- A—HUMAN NECESSITIES
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
- A61L2300/254—Enzymes, proenzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
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- Public Health (AREA)
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- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Surgery (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361920656P | 2013-12-24 | 2013-12-24 | |
| IL230150A IL230150A0 (en) | 2013-12-24 | 2013-12-24 | One-component fibrin glue containing zymogens |
| PCT/IL2014/000062 WO2015097687A1 (en) | 2013-12-24 | 2014-12-04 | One component fibrin glue comprising zymogens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2875875T3 true ES2875875T3 (es) | 2021-11-11 |
Family
ID=51691231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES14830890T Active ES2875875T3 (es) | 2013-12-24 | 2014-12-04 | Pegamento de fibrina de un componente que comprende zimógenos |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9814765B2 (enExample) |
| EP (2) | EP3875123A1 (enExample) |
| JP (2) | JP6866160B2 (enExample) |
| CN (1) | CN105979960B (enExample) |
| AU (1) | AU2014372151A1 (enExample) |
| BR (1) | BR112016014756B1 (enExample) |
| CA (1) | CA2934417A1 (enExample) |
| ES (1) | ES2875875T3 (enExample) |
| IL (3) | IL230150A0 (enExample) |
| WO (1) | WO2015097687A1 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
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| IL230150A0 (en) * | 2013-12-24 | 2014-09-30 | Omrix Biopharmaceuticals Ltd | One-component fibrin glue containing zymogens |
| IL230151A0 (en) | 2013-12-24 | 2014-09-30 | Omrix Biopharmaceuticals Ltd | One-component fibrin glue containing a polymerization inhibitor |
| IL231792A0 (en) | 2014-03-27 | 2014-08-31 | Omrix Biopharmaceuticals Ltd | Device and method for the preparation and administration of one-component fibrin glue |
| EP3274002B1 (en) * | 2015-03-27 | 2021-09-22 | 3M Innovative Properties Company | Fibrin composition, method and wound articles |
| WO2017083248A1 (en) * | 2015-11-11 | 2017-05-18 | Ethicon, Inc. | Sealant formulation and uses thereof |
| WO2017118910A1 (en) * | 2016-01-07 | 2017-07-13 | Eio Biomedical Ltd | Methods, compositions and kits for reducing tissue adhesions |
| IL247821A0 (en) * | 2016-09-14 | 2017-01-31 | Omrix Biopharmaceuticals Ltd | Adhesive preparations and their use |
| US10940233B2 (en) | 2016-10-05 | 2021-03-09 | 3M Innovative Properties Company | Fibrinogen composition, method and wound articles |
| EP3522942B1 (en) | 2016-10-05 | 2023-12-27 | 3M Innovative Properties Company | Fibrin composition comprising carrier material, method and wound articles |
| JP2021115288A (ja) * | 2020-01-28 | 2021-08-10 | 青葉化成株式会社 | 液状組成物および液状医療材料 |
| WO2022064478A1 (en) | 2020-09-23 | 2022-03-31 | Omrix Biopharmaceuticals Ltd. | Hemostatic formulations and uses thereof |
| WO2023119277A1 (en) | 2021-12-21 | 2023-06-29 | Omrix Biopharmaceuticals Ltd. | Highly soluble fibrinogen compositions |
| EP4456935A1 (en) | 2021-12-30 | 2024-11-06 | Baxter International Inc. | Fibrinogen and thrombin solutions for a fibrin sealant and fibrin sealant kit |
| AU2023230867A1 (en) * | 2022-01-07 | 2024-06-06 | Regents Of The University Of Minnesota | Hemostatic composition containing recombinant human clotting factors, and method of producing |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3622642A1 (de) | 1986-07-05 | 1988-01-14 | Behringwerke Ag | Einkomponenten-gewebekleber sowie verfahren zu seiner herstellung |
| US5219328A (en) | 1990-01-03 | 1993-06-15 | Cryolife, Inc. | Fibrin sealant delivery method |
| US5318524A (en) | 1990-01-03 | 1994-06-07 | Cryolife, Inc. | Fibrin sealant delivery kit |
| US5792835A (en) | 1991-09-05 | 1998-08-11 | Baxter International Inc. | Method of preparing a topical fibrinogen complex |
| CZ280540B6 (cs) | 1991-09-27 | 1996-02-14 | Opperbas Holding B.V. | Tkáňové lepidlo obsahující kryoprecipitát, způsob jeho výroby a použití aprotininu, proteázy z hadího jedu a batroxobinu pro jeho přípravu |
| CN1091315A (zh) | 1992-10-08 | 1994-08-31 | E·R·斯奎布父子公司 | 血纤维蛋白封闭剂组合物及其使用方法 |
| WO1997029792A1 (en) * | 1996-02-20 | 1997-08-21 | Cohesion Corporation | Tissue sealant compositions and methods of use thereof |
| FR2757770B1 (fr) * | 1996-12-30 | 1999-02-26 | Inoteb | Procede de preparation d'une colle biologique capable de coaguler par simple addition d'ions calcium |
| US6121232A (en) | 1997-01-31 | 2000-09-19 | Omrix Biopharmaceuticals Sa | Stabilized mixture comprising fibrinogen |
| EP0856317A1 (en) | 1997-01-31 | 1998-08-05 | Omrix Biopharmaceuticals S.A. | A stabilized mixture comprising fibrinogen |
| SK139099A3 (en) | 1997-04-08 | 2000-06-12 | Baxter Ag | Immunotolerant prothrombin complex preparation |
| GB9711927D0 (en) | 1997-06-09 | 1997-08-06 | Bristol Myers Squibb Co | Compositions useful as fibrin sealants |
| IL158754A0 (en) | 2001-05-21 | 2004-05-12 | Omrix Biopharm Sa | Removal of plasmin(ogen) from protein solutions |
| EP1528930B1 (de) * | 2002-07-23 | 2009-04-15 | Bio & Bio Licensing SA | Thrombingenerierfähige und thrombinhaltige pharmazeutische wirkstoffzubereitungen und arzneimittel |
| JP2005239613A (ja) * | 2004-02-25 | 2005-09-08 | Asahi Kasei Medical Co Ltd | フィブリノーゲン組成液及びその製法 |
| FR2894831B1 (fr) | 2005-12-16 | 2008-02-15 | Lab Francais Du Fractionnement | Colle biologique exempte de thrombine et son utilisation comme medicament. |
| EP2131776A1 (en) * | 2007-03-30 | 2009-12-16 | Thrombodyne Inc. | Methods of making concentrated fibrinogen containing compositions and associated systems for preparing fibrin glue |
| US8367802B2 (en) | 2009-06-18 | 2013-02-05 | Biomedica Management Corporation | Method to produce fibrin monomer in acid media for use as tissue sealant |
| DK2624859T3 (en) * | 2010-10-06 | 2017-06-06 | Medimmune Ltd | FACTOR II ALONE OR IN COMBINATION WITH OTHER FACTORS FOR TREATMENT OF REDUCED HEMOSTASE IN CONNECTION WITH DILUTION COAGULOPATHY |
| IL230150A0 (en) | 2013-12-24 | 2014-09-30 | Omrix Biopharmaceuticals Ltd | One-component fibrin glue containing zymogens |
-
2013
- 2013-12-24 IL IL230150A patent/IL230150A0/en unknown
-
2014
- 2014-12-04 IL IL291757A patent/IL291757A/en unknown
- 2014-12-04 AU AU2014372151A patent/AU2014372151A1/en not_active Abandoned
- 2014-12-04 EP EP21169115.9A patent/EP3875123A1/en not_active Withdrawn
- 2014-12-04 BR BR112016014756-1A patent/BR112016014756B1/pt not_active IP Right Cessation
- 2014-12-04 CA CA2934417A patent/CA2934417A1/en active Pending
- 2014-12-04 US US14/560,089 patent/US9814765B2/en not_active Expired - Fee Related
- 2014-12-04 EP EP14830890.1A patent/EP3086817B1/en active Active
- 2014-12-04 JP JP2016542705A patent/JP6866160B2/ja not_active Expired - Fee Related
- 2014-12-04 WO PCT/IL2014/000062 patent/WO2015097687A1/en not_active Ceased
- 2014-12-04 ES ES14830890T patent/ES2875875T3/es active Active
- 2014-12-04 CN CN201480070985.3A patent/CN105979960B/zh not_active Expired - Fee Related
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2016
- 2016-06-09 IL IL246150A patent/IL246150B/en unknown
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2017
- 2017-06-21 US US15/629,392 patent/US10555991B2/en not_active Expired - Fee Related
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2019
- 2019-09-06 JP JP2019162841A patent/JP7146712B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20150174215A1 (en) | 2015-06-25 |
| JP2017506089A (ja) | 2017-03-02 |
| WO2015097687A1 (en) | 2015-07-02 |
| JP2020000912A (ja) | 2020-01-09 |
| AU2014372151A1 (en) | 2016-06-30 |
| US9814765B2 (en) | 2017-11-14 |
| JP6866160B2 (ja) | 2021-04-28 |
| EP3086817A1 (en) | 2016-11-02 |
| EP3086817B1 (en) | 2021-05-12 |
| BR112016014756A2 (enExample) | 2017-08-08 |
| US20170290949A1 (en) | 2017-10-12 |
| IL246150A0 (en) | 2016-07-31 |
| IL230150A0 (en) | 2014-09-30 |
| CA2934417A1 (en) | 2015-07-02 |
| BR112016014756A8 (pt) | 2020-06-02 |
| US10555991B2 (en) | 2020-02-11 |
| EP3875123A1 (en) | 2021-09-08 |
| IL246150B (en) | 2022-05-01 |
| CN105979960A (zh) | 2016-09-28 |
| BR112016014756B1 (pt) | 2020-10-13 |
| CN105979960B (zh) | 2021-08-17 |
| IL291757A (en) | 2022-06-01 |
| JP7146712B2 (ja) | 2022-10-04 |
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