ES2869909T3 - Composiciones y métodos para la modificación del receptor de la proteína tensioactiva A - Google Patents

Composiciones y métodos para la modificación del receptor de la proteína tensioactiva A Download PDF

Info

Publication number
ES2869909T3
ES2869909T3 ES15822298T ES15822298T ES2869909T3 ES 2869909 T3 ES2869909 T3 ES 2869909T3 ES 15822298 T ES15822298 T ES 15822298T ES 15822298 T ES15822298 T ES 15822298T ES 2869909 T3 ES2869909 T3 ES 2869909T3
Authority
ES
Spain
Prior art keywords
cells
sequence
monoclonal antibody
seq
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES15822298T
Other languages
English (en)
Spanish (es)
Inventor
Zissis Chroneos
Neil Christensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penn State Research Foundation
Original Assignee
Penn State Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penn State Research Foundation filed Critical Penn State Research Foundation
Application granted granted Critical
Publication of ES2869909T3 publication Critical patent/ES2869909T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES15822298T 2014-07-14 2015-07-14 Composiciones y métodos para la modificación del receptor de la proteína tensioactiva A Active ES2869909T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462024314P 2014-07-14 2014-07-14
US201562121830P 2015-02-27 2015-02-27
PCT/US2015/040304 WO2016010978A1 (en) 2014-07-14 2015-07-14 Compositions and methods for targeting of the surfactant protein a receptor

Publications (1)

Publication Number Publication Date
ES2869909T3 true ES2869909T3 (es) 2021-10-26

Family

ID=55078969

Family Applications (1)

Application Number Title Priority Date Filing Date
ES15822298T Active ES2869909T3 (es) 2014-07-14 2015-07-14 Composiciones y métodos para la modificación del receptor de la proteína tensioactiva A

Country Status (8)

Country Link
US (1) US10077309B2 (https=)
EP (2) EP3733700A1 (https=)
JP (1) JP6495434B2 (https=)
CN (1) CN106604931B (https=)
AU (2) AU2015289831B2 (https=)
CA (2) CA3225495A1 (https=)
ES (1) ES2869909T3 (https=)
WO (1) WO2016010978A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112442126B (zh) * 2019-09-04 2022-07-29 杭州济元基因科技有限公司 一种抗人cs1抗原的单克隆抗体及其car-t细胞
EP4000597A1 (en) * 2020-11-17 2022-05-25 The Boots Company plc Tetrapeptide and compositions comprising tetrapeptides
CN116217718B (zh) * 2022-11-21 2023-08-25 浙江洪晟生物科技股份有限公司 一种猪丹毒抗体检测试剂盒及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE921342A1 (en) * 1991-04-26 1992-11-04 Surface Active Ltd Novel antibodies, and methods for their use
EP1649038B1 (en) 2003-06-26 2014-07-02 Litron Laboratories Ltd. Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates
US8691730B2 (en) * 2007-09-14 2014-04-08 Adimab, Llc Rationally designed, synthetic antibody libraries and uses therefor
US8748113B2 (en) 2007-11-15 2014-06-10 The Johns Hopkins University Methods for detecting and monitoring circulating cancer stem cells
WO2010010467A2 (en) * 2008-07-25 2010-01-28 Institute For Research In Biomedicine Neutralizing anti-influenza a virus antibodies and uses thereof
US9778264B2 (en) 2010-09-03 2017-10-03 Abbvie Stemcentrx Llc Identification and enrichment of cell subpopulations
CN104936977B (zh) 2012-10-24 2019-10-08 开普敦大学 微管修饰化合物

Also Published As

Publication number Publication date
CA3225495A1 (en) 2016-01-21
AU2020294340B2 (en) 2024-05-02
CN106604931A (zh) 2017-04-26
CA2954518A1 (en) 2016-01-21
JP6495434B2 (ja) 2019-04-03
US10077309B2 (en) 2018-09-18
EP3733700A1 (en) 2020-11-04
AU2015289831B2 (en) 2021-01-28
CN106604931B (zh) 2020-04-21
US20170158768A1 (en) 2017-06-08
AU2020294340A1 (en) 2021-02-25
WO2016010978A1 (en) 2016-01-21
EP3172230A1 (en) 2017-05-31
EP3172230A4 (en) 2018-04-18
JP2017527268A (ja) 2017-09-21
CA2954518C (en) 2024-02-20
AU2015289831A1 (en) 2017-02-09
EP3172230B1 (en) 2021-04-14

Similar Documents

Publication Publication Date Title
US11649292B2 (en) Compositions and methods for treating and preventing inflammation
KR102312856B1 (ko) Ror1 암을 치료하고 전이를 저해하는데 이용을 위한 항체와 백신
ES2965283T3 (es) Tratamiento de pacientes con hemoglobinuria paroxística nocturna mediante un inhibidor del complemento
ES2647359T3 (es) Tratamiento de afecciones vasculoproliferativas
ES2881303T3 (es) Método para el tratamiento o prevención del accidente cerebrovascular
US9493554B2 (en) Methods of treating retinal disorders with anti-apelin antibodies
TWI786619B (zh) 抑制scube2,一新穎vegfr2輔受體,遏止腫瘤血管新生
ES2808529T3 (es) Inhibidor del factor de células madre
JPWO2016133059A1 (ja) Fstl1を利用した抗がん剤・転移抑制剤およびその併用剤
AU2020294340B2 (en) Compositions and methods for targeting of the surfactant protein a receptor
US20230183323A1 (en) Methods for preventing, reversing or treating a covid-19 infection
ES2985731T3 (es) Tratamiento de exacerbaciones agudas de la enfermedad pulmonar obstructiva crónica mediante antagonismo de IL-20R
ES2851386T3 (es) Método de tratamiento de las heridas
BR112017010336B1 (pt) Uso de um composto que inibe a sinalização de vegf-b