ES2847897T3 - Compuestos heterocíclicos bicíclicos y sus usos en terapia - Google Patents
Compuestos heterocíclicos bicíclicos y sus usos en terapia Download PDFInfo
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- ES2847897T3 ES2847897T3 ES13780387T ES13780387T ES2847897T3 ES 2847897 T3 ES2847897 T3 ES 2847897T3 ES 13780387 T ES13780387 T ES 13780387T ES 13780387 T ES13780387 T ES 13780387T ES 2847897 T3 ES2847897 T3 ES 2847897T3
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| LT3083616T (lt) | 2013-12-20 | 2021-09-10 | Astex Therapeutics Limited | Bicikinių heterociklų junginiai ir jų panaudojimas terapijoje |
| WO2016079527A1 (en) | 2014-11-19 | 2016-05-26 | Tetralogic Birinapant Uk Ltd | Combination therapy |
| WO2016097773A1 (en) | 2014-12-19 | 2016-06-23 | Children's Cancer Institute | Therapeutic iap antagonists for treating proliferative disorders |
| GB201506871D0 (en) | 2015-04-22 | 2015-06-03 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| CN109311867A (zh) | 2016-04-20 | 2019-02-05 | 葛兰素史克知识产权开发有限公司 | 包含ripk2抑制剂的共轭物 |
| CN109071525B (zh) * | 2016-05-09 | 2022-08-19 | 豪夫迈·罗氏有限公司 | 二聚化合物 |
| CN109152843A (zh) | 2016-05-20 | 2019-01-04 | 豪夫迈·罗氏有限公司 | Protac抗体缀合物及其使用方法 |
| GB201610147D0 (en) | 2016-06-10 | 2016-07-27 | Glaxosmithkline Ip Dev Ltd | Novel compounds |
| CN106265764B (zh) | 2016-08-18 | 2018-03-16 | 广州威溶特医药科技有限公司 | Iap抑制剂和溶瘤病毒在制备抗肿瘤药物中的应用 |
| CN109535070B (zh) * | 2018-12-27 | 2022-03-29 | 青岛清原化合物有限公司 | 吡啶氧基羧酸酯衍生物及其制备方法、除草组合物和应用 |
| WO2020133092A1 (zh) | 2018-12-27 | 2020-07-02 | 青岛清原化合物有限公司 | 吡啶氧基羧酸酯衍生物及其制备方法、除草组合物和应用 |
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| CA3148504A1 (en) | 2019-08-08 | 2021-02-11 | Institute For Cancer Research D/B/A/ The Research Institute Of Fox Chase Cancer Center | Combination therapy for treatment of cancer |
| CN110483509B (zh) * | 2019-09-04 | 2020-08-25 | 温州大学 | 一种合成含氮杂环衍生物的方法 |
| CN110627785B (zh) * | 2019-09-19 | 2021-06-25 | 温州大学 | 一种1,5-四氢萘啶衍生物的制备方法 |
| US20230183234A1 (en) | 2020-05-04 | 2023-06-15 | Otsuka Pharmaceutical Co., Ltd. | Iap antagonist compounds and intermediates and methods for synthesizing the same |
| CN115916790B (zh) * | 2020-06-04 | 2025-10-24 | 百济神州有限公司 | 作为IAP拮抗剂的吡啶并[2,3-b][1,4]噁嗪或四氢吡啶并[2,3-b][1,4]氧氮杂卓 |
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| US20250179073A1 (en) * | 2022-03-11 | 2025-06-05 | Ascentage Pharma (Suzhou) Co., Ltd. | Tricyclic heterocycle compounds as iap antagonists |
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| CN104870441B (zh) | 2017-09-29 |
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| GB201218862D0 (en) | 2012-12-05 |
| JP2016500684A (ja) | 2016-01-14 |
| US9617283B2 (en) | 2017-04-11 |
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