ES2837034T3 - Inhibidores de arginina metiltransferasa y usos de los mismos - Google Patents
Inhibidores de arginina metiltransferasa y usos de los mismos Download PDFInfo
- Publication number
- ES2837034T3 ES2837034T3 ES14717371T ES14717371T ES2837034T3 ES 2837034 T3 ES2837034 T3 ES 2837034T3 ES 14717371 T ES14717371 T ES 14717371T ES 14717371 T ES14717371 T ES 14717371T ES 2837034 T3 ES2837034 T3 ES 2837034T3
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- certain embodiments
- optionally substituted
- carbocyclyl
- heterocyclyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229910052739 hydrogen Inorganic materials 0.000 claims abstract description 190
- 239000001257 hydrogen Substances 0.000 claims abstract description 190
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- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims abstract description 165
- -1 methoxyethyl Chemical group 0.000 claims abstract description 159
- 125000001072 heteroaryl group Chemical group 0.000 claims abstract description 154
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- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims abstract description 72
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Classifications
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- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/415—1,2-Diazoles
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
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- 2014-03-14 BR BR112015022785A patent/BR112015022785A2/pt not_active Application Discontinuation
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